{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:41:26Z","timestamp":1792788086011,"version":"4.5.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Zunyi Science and Technology Bureau","award":["\uff082018\uff0985"],"award-info":[{"award-number":["\uff082018\uff0985"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diagn Pathol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ovarian fibroma is the most common benign pure stromal tumor. It has no specific clinical manifestation, most of which are pelvic or adnexal masses. 10-15% of cases with hydrothorax or ascites, after tumor resection, hydrothorax and ascites disappear, known as Meigs Syndrome. The elevated level of CA125 in a few patients was easily misdiagnosed as ovarian malignant tumor. A case of bilateral Ovarian fibroma associated with Meigs Syndrome is reported and the literature is reviewed in order to improve the understanding of the changes and avoid misdiagnosis.<\/jats:p>","DOI":"10.1186\/s13000-022-01258-9","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T02:02:22Z","timestamp":1665972142000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A case of death of patient with ovarian fibroma combined with Meigs Syndrome and literature review"],"prefix":"10.1186","volume":"17","author":[{"given":"Na","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-yuan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-rong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-fang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"issue":"5","key":"1258_CR1","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1007\/s00261-014-0257-z","volume":"40","author":"BM Chung","year":"2015","unstructured":"Chung BM, Park SB, Lee JB, Park HJ, Kim YS, Oh YJ. Magnetic resonance imaging features of ovarian fibroma, fibrothecoma, and thecoma. Abdom Imaging. 2015;40(5):1263\u201372.","journal-title":"Abdom Imaging"},{"issue":"11\u201312","key":"1258_CR2","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1007\/s00383-004-1284-6","volume":"20","author":"YJ Chen","year":"2004","unstructured":"Chen YJ, Hsieh CS, Eng HL, Huang CC. Ovarian fibroma in a 7-month-old infant: a case report and review of the literature. Pediatr Surg Int. 2004;20(11\u201312):894\u20137.","journal-title":"Pediatr Surg Int"},{"issue":"2","key":"1258_CR3","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1007\/s12013-014-0288-7","volume":"71","author":"Z Zhang","year":"2015","unstructured":"Zhang Z, Wu Y, Gao J. CT diagnosis in the thecoma-fibroma group of the ovarian stromal tumors. Cell Biochem Biophys. 2015;71(2):937\u201343.","journal-title":"Cell Biochem Biophys"},{"issue":"3","key":"1258_CR4","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1097\/RUQ.0000000000000144","volume":"31","author":"ME Hogan","year":"2015","unstructured":"Hogan ME, Andreotti R. Ovarian Fibroma Presenting With Meigs Syndrome. Ultrasound Q. 2015;31(3):215\u20138.","journal-title":"Ultrasound Q"},{"issue":"3","key":"1258_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/ajo.12090","volume":"53","author":"C Numanoglu","year":"2013","unstructured":"Numanoglu C, Kuru O, Sakinci M, Akbay\u0131r O, Ulker V. Ovarian fibroma\/fibrothecoma: retrospective cohort study shows limited value of risk of malignancy index score. Aust N Z J Obstet Gynaecol. 2013;53(3):287\u201392.","journal-title":"Aust N Z J Obstet Gynaecol"},{"issue":"34","key":"1258_CR6","doi-asserted-by":"publisher","first-page":"e11926","DOI":"10.1097\/MD.0000000000011926","volume":"97","author":"Y Shen","year":"2018","unstructured":"Shen Y, Liang Y, Cheng X, Lu W, Xie X, Wan X. Ovarian fibroma\/fibrothecoma with elevated serum CA125 level: A cohort of 66 cases. Med (Baltim). 2018;97(34):e11926.","journal-title":"Med (Baltim)"},{"issue":"2","key":"1258_CR7","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/00005382-200304000-00009","volume":"18","author":"AJ Nemeth","year":"2003","unstructured":"Nemeth AJ, Patel SK. Meigs syndrome revisited. J Thorac Imaging. 2003;18(2):100\u20133.","journal-title":"J Thorac Imaging"},{"issue":"4","key":"1258_CR8","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/S1028-4559(09)60003-6","volume":"47","author":"MH Cheng","year":"2008","unstructured":"Cheng MH, Yen MS, Chao KC, Sheu BC, Wang PH. Differential diagnosis of gynecologic organ-related diseases in women presenting with ascites. Taiwan J Obstet Gynecol. 2008;47(4):384\u201390.","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"3","key":"1258_CR9","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1097\/01.pgp.0000192271.22289.e6","volume":"25","author":"LM Roth","year":"2006","unstructured":"Roth LM. Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 2006;25(3):199\u2013215.","journal-title":"Int J Gynecol Pathol"},{"key":"1258_CR10","unstructured":"Mohammed SA, Kumar A. Meigs Syndrome. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2021."},{"issue":"5","key":"1258_CR11","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.1016\/j.reuma.2017.04.003","volume":"15","author":"AR Torres Jim\u00e9nez","year":"2019","unstructured":"Torres Jim\u00e9nez AR, Sol\u00eds-Vallejo E, C\u00e9spedes-Cruz AI, Zeferino Cruz M, Rojas-Curiel EZ, S\u00e1nchez-Jara B. Tjalma syndrome (pseudo-pseudo Meigs\u2019) as initial manifestation of juvenile-onset systemic lupus erythematosus. S\u00edndrome de Tjalma (pseudo-pseudo Meigs) como manifestaci\u00f3n inicial de lupus eritematoso sist\u00e9mico de inicio juvenil. Reumatol Clin (Engl Ed). 2019;15(5):e41\u20133.","journal-title":"Reumatol Clin (Engl Ed)"}],"container-title":["Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13000-022-01258-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13000-022-01258-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13000-022-01258-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T02:04:47Z","timestamp":1665972287000},"score":1,"resource":{"primary":{"URL":"https:\/\/diagnosticpathology.biomedcentral.com\/articles\/10.1186\/s13000-022-01258-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,17]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["1258"],"URL":"https:\/\/doi.org\/10.1186\/s13000-022-01258-9","relation":{},"ISSN":["1746-1596"],"issn-type":[{"value":"1746-1596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,17]]},"assertion":[{"value":"23 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for the publication of this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"83"}}