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In this case, a mass of 8.3\u00a0cm in diameter was found in a 59-year-old male patient\u2019s right retroperitoneum, as revealed by abdominal contrast-enhanced computed tomography (CT) images. The tumor exhibited a well-circumscribed nature and histological features characterized by a combination of hemangiopericytomatous vasculature and mature adipose tissue, comprising around 70% of the total tumor composition. Immunohistochemistry staining revealed diffuse positive expression of STAT6 and CD34 in the tumor cells. Based on these findings, the final diagnosis was determined to be a fat-forming solitary fibrous tumor located in the retroperitoneum. It is important to consider other potential differential diagnoses, including angiomyolipoma, dedifferentiated liposarcoma, spindle cell lipoma, and atypical lipomatous tumor\/well-differentiated liposarcoma.<\/jats:p>","DOI":"10.1186\/s13000-024-01463-8","type":"journal-article","created":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T11:03:17Z","timestamp":1708599797000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A case of fat-forming solitary fibrous tumor that is prone to be confused with liposarcoma"],"prefix":"10.1186","volume":"19","author":[{"given":"Yi-Dan","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Qing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Rong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin Jing","family":"Pi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Zhen","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"1463_CR1","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1097\/00000478-199507000-00002","volume":"19","author":"GP Nielsen","year":"1995","unstructured":"Nielsen GP, Dickersin GR, Provenzal JM, Rosenberg AE. 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