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Owing to its rarity, Mixed pattern RMS (ARMS and ERMS) constitutes a diagnostic and therapeutic dilemma.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case<\/jats:title>\n                <jats:p>Herein is presented a very rare case of mixed alveolar &amp; embryonal rhabdomyosarcoma in the uterus of a 68-year-old woman. The wall of the uterine corpus &amp; cervix was replaced by multiple whitish\u2013yellow, firm nodules, measuring up to 12\u00a0cm. Microscopically, the tumor was predominantly composed of round to polygonal cells arranged in nests with alveolar pattern intermingled with hypo- &amp; hypercellular areas of more primitive cells with scattered multinucleated giant cells seen as well. Extensive sampling failed to show epithelial elements. Immunohistochemical staining showed positive staining for vimentin, desmin, myogenin, CD56 &amp; WT-1. However, no staining was detected for CK, LCA, CD10, ER, SMA, CD99, S100, Cyclin-D1 &amp; Olig-2. Metastatic deposits were found in the peritoneum. The patient received postoperative chemotherapy and radiotherapy but died of systemic metastases 3\u00a0months after surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The rarity of this histological tumor entity and its aggressive behavior and poor prognosis grab attention to improving recognition and treatment modalities in adults.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13000-024-01518-w","type":"journal-article","created":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T09:02:12Z","timestamp":1721206932000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare adult case of primary uterine rhabdomyosarcoma with mixed pattern: a clinicopathological &amp; immunohistochemical study with literature review"],"prefix":"10.1186","volume":"19","author":[{"given":"Nehal K.H.","family":"Kamel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiman Adel","family":"Hasby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,17]]},"reference":[{"issue":"5","key":"1518_CR1","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1053\/j.sempedsurg.2016.09.011","volume":"25","author":"R Dasgupta","year":"2016","unstructured":"Dasgupta R, Fuchs J, Rodeberg D. 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