{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:54:41Z","timestamp":1791561281273,"version":"4.3.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah","award":["165-005-D1434"],"award-info":[{"award-number":["165-005-D1434"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head Face Med"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s13005-016-0102-4","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T00:47:51Z","timestamp":1454028471000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Expression of cell adhesion molecule CD44 in mucoepidermoid carcinoma and its association with the tumor behavior"],"prefix":"10.1186","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2200-6206","authenticated-orcid":false,"given":"Nada","family":"Binmadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza","family":"Elsissi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Elsissi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,1,29]]},"reference":[{"key":"102_CR1","unstructured":"Gnepp DR. Diagnostic Surgical Pathology of the Head and Neck. 2nd ed. Philadilphia: WB Saunders Co; 2009."},{"issue":"8","key":"102_CR2","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.bjoms.2009.03.017","volume":"47","author":"PM Speight","year":"2009","unstructured":"Speight PM, Barrett AW. Prognostic factors in malignant tumours of the salivary glands. Br J Oral Maxillofac Surg. 2009;47(8):587\u201393.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"102_CR3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0065-230X(08)60101-3","volume":"71","author":"D Naor","year":"1997","unstructured":"Naor D, Sionov RV, Ish-Shalom D. CD44: structure, function, and association with the malignant process. Adv Cancer Res. 1997;71:241\u2013319.","journal-title":"Adv Cancer Res"},{"issue":"6","key":"102_CR4","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1080\/10408360290795574","volume":"39","author":"D Naor","year":"2002","unstructured":"Naor D, Nedvetzki S, Golan I, Melnik L, Faitelson Y. CD44 in cancer. Crit Rev Clin Lab Sci. 2002;39(6):527\u201379.","journal-title":"Crit Rev Clin Lab Sci"},{"key":"102_CR5","doi-asserted-by":"crossref","unstructured":"Breukelmann D, Bier B, Rempe D, Pschadka G, Bo W. Gains and losses of CD44 expression during breast carcinogenesis and tumour progression. 1998;107\u201316.","DOI":"10.1046\/j.1365-2559.1998.00472.x"},{"key":"102_CR6","doi-asserted-by":"crossref","unstructured":"Lalit Mohan Negi, Sushama Talegaonkar, Manu Jaggi FJA, Zeenat Iqbal, Khar RK. Role of CD44 in tumour progression and strategies for targeting. J Drug Target. 2012;20(7):561\u201373.","DOI":"10.3109\/1061186X.2012.702767"},{"key":"102_CR7","doi-asserted-by":"crossref","unstructured":"Naor D, Sionov R, Ish-Shalom D. CD44: Structre, Function and Association with the Malignant Process. Adv Cancer Res. 1997;71:241\u2013319.","DOI":"10.1016\/S0065-230X(08)60101-3"},{"issue":"3","key":"102_CR8","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1177\/1535370213480714","volume":"238","author":"K Williams","year":"2013","unstructured":"Williams K, Motiani K, Giridhar PV, Kasper S. CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches. Exp Biol Med (Maywood). 2013;238(3):324\u201338.","journal-title":"Exp Biol Med (Maywood)"},{"key":"102_CR9","doi-asserted-by":"crossref","unstructured":"Page MJ. Chapter 13 The Role of Hyaluronan in Cancer. Chemistry and bioligy of Hyaluronan. 2004. p. 285\u2013305.","DOI":"10.1016\/B978-008044382-9\/50044-3"},{"issue":"2","key":"102_CR10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.breast.2011.09.004","volume":"21","author":"S Simonetti","year":"2012","unstructured":"Simonetti S, Terracciano L, Zlobec I, Kilic E, Stasio L, Quarto M, et al. Immunophenotyping analysis in invasive micropapillary carcinoma of the breast: role of CD24 and CD44 isoforms expression. Breast. 2012;21(2):165\u201370. Elsevier Ltd.","journal-title":"Breast"},{"issue":"2","key":"102_CR11","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s12105-012-0407-y","volume":"7","author":"SG Fitzpatrick","year":"2013","unstructured":"Fitzpatrick SG, Montague LJ, Cohen DM, Bhattacharyya I. CD44 expression in intraoral salivary ductal papillomas and oral papillary squamous cell carcinoma. Head Neck Pathol. 2013;7(2):122\u20138.","journal-title":"Head Neck Pathol"},{"issue":"1","key":"102_CR12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s12105-009-0102-9","volume":"3","author":"RR Seethala","year":"2009","unstructured":"Seethala RR. An update on grading of salivary gland carcinomas. Head Neck Pathol. 2009;3(1):69\u201377.","journal-title":"Head Neck Pathol"},{"issue":"7","key":"102_CR13","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1080\/003655402\/000028047","volume":"122","author":"MS Brandwein","year":"2002","unstructured":"Brandwein MS, Ferlito A, Bradley PJ, Hille JJ, Rinaldo A. Diagnosis and classification of salivary neoplasms: pathologic challenges and relevance to clinical outcomes. Acta Otolaryngol. 2002;122(7):758\u201364.","journal-title":"Acta Otolaryngol"},{"issue":"2","key":"102_CR14","first-page":"155","volume":"11","author":"DC Allred","year":"1998","unstructured":"Allred DC, Allred DC, Harvey JM, Berardo M, Clark GM. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol. 1998;11(2):155\u201368.","journal-title":"Mod Pathol"},{"issue":"8","key":"102_CR15","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1002\/1097-0142(19920415)69:8<2021::AID-CNCR2820690803>3.0.CO;2-7","volume":"69","author":"PL Auclair","year":"1992","unstructured":"Auclair PL, Goode RK, Ellis GL. Mucoepidermoid carcinoma of intraoral salivary glands. Evaluation and application of grading criteria in 143 cases. Cancer. 1992;69(8):2021\u201330.","journal-title":"Cancer"},{"issue":"8","key":"102_CR16","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1111\/j.1601-0825.2009.01591.x","volume":"15","author":"SM Chang","year":"2009","unstructured":"Chang SM, Xing RD, Zhang FM, Duan YQ. Serum soluble CD44v6 levels in patients with oral and maxillofacial malignancy. Oral Dis. 2009;15(8):570\u20132.","journal-title":"Oral Dis"},{"issue":"4","key":"102_CR17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1601-0825.1998.tb00287.x","volume":"4","author":"R Xing","year":"1998","unstructured":"Xing R, Regezi J a, Stern M, Shuster S, Stern R. Hyaluronan and CD44 expression in minor salivary gland tumors. Oral Dis. 1998;4(4):241\u20137.","journal-title":"Oral Dis"},{"issue":"6","key":"102_CR18","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.oooo.2013.09.004","volume":"116","author":"TC Fok","year":"2013","unstructured":"Fok TC, Lapointe H, Tuck a B, Chambers a F, Jackson-Boeters L, Daley TD, et al. Expression and localization of osteopontin, homing cell adhesion molecule\/CD44, and integrin \u03b1v\u03b23 in pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116(6):743\u201351. Elsevier Inc.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"2","key":"102_CR19","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/hed.20307","volume":"28","author":"RO Wein","year":"2006","unstructured":"Wein RO, McGary CT, Doerr TD, Popat SR, Howard JL, Weigel J a, et al. Hyaluronan and its receptors in mucoepidermoid carcinoma. Head Neck. 2006;28(2):176\u201381 [Internet].","journal-title":"Head Neck"},{"issue":"7","key":"102_CR20","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1111\/his.12109","volume":"62","author":"RCF Ianez","year":"2013","unstructured":"Ianez RCF, Coutinho-Camillo CM, Buim ME, Pinto C a L, Soares F a, Louren\u00e7o SV. CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators? Histopathology. 2013;62(7):1075\u201382.","journal-title":"Histopathology"},{"key":"102_CR21","doi-asserted-by":"crossref","unstructured":"Fonseca I, Nunes JFM, Soares J. Expression of CD44 isoforms in normal salivary gland tissue : an immunohistochemical and ultrastructural study. 2000;483\u20138.","DOI":"10.1007\/s004180000220"}],"container-title":["Head &amp; Face Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13005-016-0102-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T15:14:29Z","timestamp":1600096469000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.head-face-med.com\/content\/12\/1\/8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,29]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["102"],"URL":"https:\/\/doi.org\/10.1186\/s13005-016-0102-4","relation":{},"ISSN":["1746-160X"],"issn-type":[{"value":"1746-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,29]]},"article-number":"8"}}