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Neuroscience. 2013;252:289\u2013301.","journal-title":"Neuroscience"}],"container-title":["Head & Face Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13005-018-0185-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13005-018-0185-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13005-018-0185-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T19:05:56Z","timestamp":1578078356000},"score":1,"resource":{"primary":{"URL":"https:\/\/head-face-med.biomedcentral.com\/articles\/10.1186\/s13005-018-0185-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,4]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["185"],"URL":"https:\/\/doi.org\/10.1186\/s13005-018-0185-1","relation":{},"ISSN":["1746-160X"],"issn-type":[{"value":"1746-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,4]]},"assertion":[{"value":"20 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"For Experimental Use of PDL fibroblasts:Approval of the Ethics Committee of the University of Bonn was obtained (#117\/15).The donors of the PDL fibroblasts or their legal guardians gave written informed consent.For Human Tissue Biopsies:Approval of the Ethics Committee of the University of Bonn was obtained (#043\/11).The donors of the tissue biopsies gave written and informed consent.For the Experimental Periodontitis Model:Approval of the Ethical Committee on Animal Experimentation from the School of Dentistry at Araraquara, S\u00e3o Paulo State University \u2013 UNESP, was obtained (protocol number: 23\/2012). Protocol followed the ARRIVE guidelines.For the Diet-induced Obesity Model:All procedures in the present study were conducted according to the ethical standards of the University of Bonn (Az 87\u201351.04.2010.A394). All applicable international, national, and\/or institutional guidelines for the care and use of animals were followed.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"2"}}