{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:28:12Z","timestamp":1793996892359,"version":"4.8.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medizinische Hochschule Hannover (MHH)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head Face Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose of the study<\/jats:title>\n                    <jats:p>\n                      This study demonstrates and investigates the feasibility of a novel approach for dental rehabilitation in complex maxillary and midfacial defects, often resulting in severe pseudo-class III relationships. It explores the use of patient-specific subperiosteal implants (IPS Implants\n                      <jats:sup>\u00ae<\/jats:sup>\n                      Preprosthetic) with innovative design variations that anchor to the skull base from below and laterally, extending beyond traditional implants to provide enhanced stability in cases of significant bone loss.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with significant maxillary and midfacial bone loss due to postablative defects were included in our case series, with or without irradiation. From 100 patients, 13 required design modifications based on FEM analysis, involving implant anchorage to the lateral skull base and\/or pterygoid process. Eight patients received single-sided lateral skull base extensions; one posttraumatic case required bilateral extensions. In five of 13 cases, additional extensions to the pterygoid process were implemented. One case needed both bilateral skull base and pterygoid extensions, while two had bilateral pterygoid and a single-sided skull base extension. Outcomes assessed included primary stability, prosthodontic restoration, complications, and soft tissue management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No implant failures occurred during follow-up, with functional stability established immediately post-insertion. Prosthodontic restoration succeeded in all cases, with no stability loss or periimplantitis. Mucositis was noted around posterior posts in some instances, and one bar required trimming due to soft tissue changes, without affecting implant function. One implant had to be removed, due to chronic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Patient-specific IPS Implants\n                      <jats:sup>\u00ae<\/jats:sup>\n                      Preprosthetic with design extensions provide a biologically suitable solution for stable dental rehabilitation in severe maxillary and midfacial structure loss, without biomechanical limitations. Achieving rigid fixation distant from the soft tissue transition is crucial for success.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13005-025-00549-y","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T04:06:19Z","timestamp":1766030779000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Innovative landing zones for one-piece, rigidly fixated patient-specific subperiosteal implants in dental rehabilitation of severe maxillary and midfacial defects"],"prefix":"10.1186","volume":"22","author":[{"given":"Nils-Claudius","family":"Gellrich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Korn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Jehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fritjof","family":"Lentge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael-Tobias","family":"Neuhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Rahlf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"issue":"2","key":"549_CR1","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1055\/s-0034-1371356","volume":"7","author":"F Wilde","year":"2014","unstructured":"Wilde F, Cornelius CP, Schramm A. 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The study was performed in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All patients provided consent for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"NCG and PK received speakers\u2019 honoraria from DePuys Synthes\n                      \u00ae\n                      , West Chester, PA, USA, Brainlab AG, Munich, Germany, KLS Martin Group, Tuttlingen, Germany and Dentsply Sirona Deutschland GmbH, Bensheim, Germany. BR received speaker\u2019s honoraria from KLS Martin Group, Tuttlingen, Germany.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"7"}}