{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:53:20Z","timestamp":1781650400437,"version":"3.54.5"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005296","name":"Universit\u00e4tsklinikum Regensburg","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005296","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Head Face Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Benign salivary gland tumors are in general rare. Pleomorphic adenomas (PA) and Warthin\u2019s tumors (WT) make up to 90% of these tumors. Their epidemiology shows significant regional differences but also changes over time. In addition to that, new developments in the surgical approach, like extracapsular dissection (ED), have been introduced.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed epidemiological and clinical data of 347 patients (184 male and 163 female) treated in the ENT-Department of the University Hospital of Regensburg in 2010\/11 and 2020\/21 and assessed their changes over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>WT is by far the most common benign tumor of the parotid gland, followed by PA and the age of diagnosis shows an increasing tendency. The hospitalization time showed a significant reduction after a period of ten years. Patients treated with ED are being hospitalized for a shorter period of time. Regular smokers tend to present more WT and are being diagnosed at younger age. Patients with WT have a higher body mass index (BMI) than other patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Over the last decade, WT remained the most common benign parotid tumor in Southeast Bavaria, while the implementation of ED has potentially impacted clinical resource utilization coincide with reduced duration of inpatient hospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13005-026-00618-w","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T10:31:46Z","timestamp":1776249106000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Changing trends in the epidemiology and surgical treatment of benign parotid gland tumours: a 10-year retrospective comparison in a tertiary referral centre of southeast Bavaria"],"prefix":"10.1186","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2457-7635","authenticated-orcid":false,"given":"Ioannis","family":"Michaelides","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Symeou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"W\u00e4llisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Meier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Bohr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"K\u00fcnzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"618_CR1","doi-asserted-by":"publisher","first-page":"4739","DOI":"10.1007\/s00405-023-08110-w","volume":"280","author":"M \u017burek","year":"2023","unstructured":"\u017burek M, Fus \u0141, Niemczyk K, Rzepakowska A. Salivary gland pathologies: evolution in classification and association with unique genetic alterations. Eur Arch Otorhinolaryngol. 2023;280:4739\u201350.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"618_CR2","doi-asserted-by":"crossref","unstructured":"Skalova A, Hyrcza MD. Proceedings of the north american society of head and neck pathology companion meeting. New Orleans, LA, March 12, 2023: classification of salivary gland tumors: remaining controversial issues? head and neck pathology., 2023;17:285\u201391.","DOI":"10.1007\/s12105-023-01541-1"},{"key":"618_CR3","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.otc.2015.10.005","volume":"49","author":"KY Zhan","year":"2016","unstructured":"Zhan KY, Khaja SF, Flack AB, Day TA. Benign parotid tumors. Otolaryngol Clin North Am. 2016;49:327\u201342.","journal-title":"Otolaryngol Clin North Am"},{"key":"618_CR4","doi-asserted-by":"publisher","unstructured":"Chloupek A, Jurkiewicz D, Kania J. The characteristics of Polish patients with salivary gland tumors: a ten-year single-center experience. Clin Oral Invest. 2023;28:3. https:\/\/doi.org\/10.1007\/s00784-023-05396-2.","DOI":"10.1007\/s00784-023-05396-2"},{"key":"618_CR5","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/coa.12694","volume":"41","author":"JC Luers","year":"2016","unstructured":"Luers JC, Guntinas-Lichius O, Klussmann JP, et al. The incidence of Warthin tumours and pleomorphic adenomas in the parotid gland over a 25\u2010year period. Clin Otolaryngol. 2016;41:793\u20137.","journal-title":"Clin Otolaryngol"},{"key":"618_CR6","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1007\/s00405-020-05894-z","volume":"277","author":"G Psychogios","year":"2020","unstructured":"Psychogios G, Vlastos I, Th\u00f6lken R, Zenk J. Warthin\u2019s tumour seems to be the most common benign neoplasm of the parotid gland in Germany. Eur Arch Otorhinolaryngol. 2020;277:2081\u20134.","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"618_CR7","doi-asserted-by":"publisher","first-page":"426","DOI":"10.3109\/00016487409124645","volume":"77","author":"CM Eneroth","year":"1974","unstructured":"Eneroth CM, Zetterberg A. Malignancy in pleomorphic adenoma: a clinical and microspectrophotometric study. Acta Otolaryngol. 1974;77:426\u201332.","journal-title":"Acta Otolaryngol"},{"key":"618_CR8","doi-asserted-by":"publisher","first-page":"1356","DOI":"10.1016\/j.jcms.2019.06.009","volume":"47","author":"M Schapher","year":"2019","unstructured":"Schapher M, Koch M, Agaimy A, et al. Parotid pleomorphic adenomas: Factors influencing surgical techniques, morbidity, and long-term outcome relative to the new ESGS classification in a retrospective study. J Craniomaxillofac Surg. 2019;47:1356\u201362.","journal-title":"J Craniomaxillofac Surg"},{"key":"618_CR9","doi-asserted-by":"crossref","unstructured":"Gawand S, Gattani RG, Aravind Kumar C, Pande A. Extracapsular dissection versus traditional parotid surgery: a comprehensive review of techniques and outcomes. Cureus. 2024.","DOI":"10.7759\/cureus.69141"},{"key":"618_CR10","doi-asserted-by":"publisher","first-page":"99","DOI":"10.5603\/njo.98175","volume":"74","author":"K Kolary-Siekierska","year":"2024","unstructured":"Kolary-Siekierska K, Ja\u0142ocha-Kaczka A, Niewiadomski P, Mi\u0142o\u0144ski J. Warthin tumors \u2013 risk factors, diagnostics, treatment. Nowotwory J Oncol. 2024;74:99\u2013104.","journal-title":"Nowotwory J Oncol"},{"key":"618_CR11","doi-asserted-by":"publisher","first-page":"29","DOI":"10.5604\/01.3001.0015.9816","volume":"76","author":"W Jaremek-Ochniak","year":"2022","unstructured":"Jaremek-Ochniak W, Skulimowska J, Plachta I, et al. Epidemiological and clinical characteristics of 407 salivary glands neoplasms in surgically treated patients in 2010\u20132020. Otolaryngol Pol. 2022;76:29\u201336.","journal-title":"Otolaryngol Pol"},{"key":"618_CR12","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.oraloncology.2017.01.004","volume":"66","author":"MH Valstar","year":"2017","unstructured":"Valstar MH, de Ridder M, van den Broek EC, et al. Salivary gland pleomorphic adenoma in the Netherlands: a nationwide observational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence. Oral Oncol. 2017;66:93\u20139.","journal-title":"Oral Oncol"},{"key":"618_CR13","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.bjoms.2012.10.002","volume":"51","author":"PJ Bradley","year":"2013","unstructured":"Bradley PJ, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. 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Eur Arch Otorhinolaryngol. 2021;278:15\u201329.","journal-title":"Eur Arch Otorhinolaryngol"}],"container-title":["Head &amp; Face Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13005-026-00618-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13005-026-00618-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13005-026-00618-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:06:05Z","timestamp":1781647565000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13005-026-00618-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,15]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["618"],"URL":"https:\/\/doi.org\/10.1186\/s13005-026-00618-w","relation":{},"ISSN":["1746-160X"],"issn-type":[{"value":"1746-160X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,15]]},"assertion":[{"value":"16 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the ethics committee of the University of Regensburg (Votum: 24-3753-104). This study was conducted in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics declaration"}},{"value":"not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"43"}}