{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T07:07:40Z","timestamp":1784358460567,"version":"3.55.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T00:00:00Z","timestamp":1554681600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science, Korea through the R&D program","award":["NRF-2017M3A9E8029717"],"award-info":[{"award-number":["NRF-2017M3A9E8029717"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiat Oncol"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s13014-019-1263-7","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T14:03:47Z","timestamp":1554732227000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Combining deep-inspiration breath hold and intensity-modulated radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma: Dosimetric evaluation using comprehensive plan quality indices"],"prefix":"10.1186","volume":"14","author":[{"given":"Seo Hee","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason Joon Bock","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Geol","family":"Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Sung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2106-6856","authenticated-orcid":false,"given":"Hong In","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,4,8]]},"reference":[{"issue":"1","key":"1263_CR1","doi-asserted-by":"publisher","first-page":"28","DOI":"10.5045\/kjh.2012.47.1.28","volume":"47","author":"HJ Park","year":"2012","unstructured":"Park HJ, Park EH, Jung KW, et al. Statistics of hematologic malignancies in Korea: incidence, prevalence and survival rates from 1999 to 2008. Korean J Hematol. 2012;47(1):28\u201338.","journal-title":"Korean J Hematol"},{"issue":"5","key":"1263_CR2","doi-asserted-by":"publisher","first-page":"757","DOI":"10.3349\/ymj.2003.44.5.757","volume":"44","author":"JS Hahn","year":"2003","unstructured":"Hahn JS, Kim YS, Lee YC, et al. Eleven-year experience of low grade lymphoma in Korea (based on REAL classification). Yonsei Med J. 2003;44(5):757\u201370.","journal-title":"Yonsei Med J"},{"issue":"5","key":"1263_CR3","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.1200\/JCO.1998.16.5.1916","volume":"16","author":"NR Schechter","year":"1998","unstructured":"Schechter NR, Portlock CS, Yahalom J. Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone. J Clin Oncol. 1998;16(5):1916\u201321.","journal-title":"J Clin Oncol"},{"issue":"22","key":"1263_CR4","doi-asserted-by":"publisher","first-page":"4157","DOI":"10.1200\/JCO.2003.06.085","volume":"21","author":"RW Tsang","year":"2003","unstructured":"Tsang RW, Gospodarowicz MK, Pintilie M, et al. Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol. 2003;21(22):4157\u201364.","journal-title":"J Clin Oncol"},{"issue":"3","key":"1263_CR5","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.radonc.2008.02.012","volume":"87","author":"C Vrieling","year":"2008","unstructured":"Vrieling C, de Jong D, Boot H, et al. Long-term results of stomach-conserving therapy in gastric MALT lymphoma. Radiother Oncol. 2008;87(3):405\u201311.","journal-title":"Radiother Oncol"},{"issue":"16","key":"1263_CR6","doi-asserted-by":"publisher","first-page":"3815","DOI":"10.1002\/cncr.25226","volume":"116","author":"JS Goda","year":"2010","unstructured":"Goda JS, Gospodarowicz M, Pintilie M, et al. Long-term outcome in localized extranodal mucosa-associated lymphoid tissue lymphomas treated with radiotherapy. Cancer. 2010;116(16):3815\u201324.","journal-title":"Cancer."},{"issue":"5","key":"1263_CR7","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1093\/annonc\/mds623","volume":"24","author":"A Wirth","year":"2013","unstructured":"Wirth A, Gospodarowicz M, Aleman BM, et al. Long-term outcome for gastric marginal zone lymphoma treated with radiotherapy: a retrospective, multi-Centre, international Extranodal lymphoma study group study. Ann Oncol. 2013;24(5):1344\u201351.","journal-title":"Ann Oncol"},{"issue":"3","key":"1263_CR8","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1093\/annonc\/mdn668","volume":"20","author":"PG Gobbi","year":"2009","unstructured":"Gobbi PG, Corbella F, Valentino F, et al. Complete long-term response to radiotherapy of gastric early-stage marginal zone lymphoma resistant to both anti-helicobacter pylori antibiotics and chemotherapy. Ann Oncol. 2009;20(3):465\u20138.","journal-title":"Ann Oncol"},{"issue":"9","key":"1263_CR9","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.6004\/jnccn.2016.0117","volume":"14","author":"SM Horwitz","year":"2016","unstructured":"Horwitz SM, Zelenetz AD, Gordon LI, et al. NCCN guidelines insights: non-Hodgkin's lymphomas, version 3.2016. J Natl Compr Cancer Netw. 2016;14(9):1067\u201379.","journal-title":"J Natl Compr Cancer Netw"},{"issue":"3","key":"1263_CR10","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.ijrobp.2004.10.025","volume":"62","author":"C Della Biancia","year":"2005","unstructured":"Della Biancia C, Hunt M, Furhang E, et al. Radiation treatment planning techniques for lymphoma of the stomach. Int J Radiat Oncol Biol Phys. 2005;62(3):745\u201351.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"1263_CR11","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1093\/jrr\/rru052","volume":"55","author":"K Inaba","year":"2014","unstructured":"Inaba K, Okamoto H, Wakita A, et al. Radiotherapy for gastric lymphoma: a planning study of 3D conformal radiotherapy, the half-beam method, and intensity-modulated radiotherapy. J Radiat Res. 2014;55(6):1141\u20135.","journal-title":"J Radiat Res"},{"issue":"3","key":"1263_CR12","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3857\/roj.2016.01865","volume":"34","author":"HW Lim","year":"2016","unstructured":"Lim HW, Kim TH, Choi IJ, et al. Radiation therapy for gastric mucosa-associated lymphoid tissue lymphoma: dose-volumetric analysis and its clinical implications. Radiat Oncol J. 2016;34(3):193\u2013201.","journal-title":"Radiat Oncol J."},{"issue":"1","key":"1263_CR13","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3857\/roj.2016.01942","volume":"35","author":"SH Bae","year":"2017","unstructured":"Bae SH, Kim DW, Kim MS, et al. Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma: dosimetric comparison and risk assessment of solid secondary cancer. Radiat Oncol J. 2017;35(1):78\u201389.","journal-title":"Radiat Oncol J"},{"key":"1263_CR14","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1186\/1748-717X-8-207","volume":"8","author":"AA Nour","year":"2013","unstructured":"Nour AA, Alaradi A, Mohamed A, et al. Intensity modulated radiotherapy of upper abdominal malignancies: dosimetric comparison with 3D conformal radiotherapy and acute toxicity. Radiat Oncol. 2013;8:207.","journal-title":"Radiat Oncol"},{"issue":"4","key":"1263_CR15","doi-asserted-by":"publisher","first-page":"332","DOI":"10.3857\/roj.2018.00402","volume":"36","author":"JH Chung","year":"2018","unstructured":"Chung JH, Na K, Kim IH. Benefit of volumetric-modulated arc therapy over three-dimensional conformal radiotherapy for stage I-II extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in the stomach: a dosimetric comparison. Radiat Oncol J. 2018;36(4):332\u201340.","journal-title":"Radiat Oncol J."},{"issue":"5","key":"1263_CR16","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1016\/j.ijrobp.2010.08.008","volume":"81","author":"JD Ruben","year":"2011","unstructured":"Ruben JD, Lancaster CM, Jones P, et al. A comparison of out-of-field dose and its constituent components for intensity-modulated radiation therapy versus conformal radiation therapy: implications for carcinogenesis. Int J Radiat Oncol Biol Phys. 2011;81(5):1458\u201364.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"1263_CR17","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1269\/jrr.11127","volume":"53","author":"M Matoba","year":"2012","unstructured":"Matoba M, Oota K, Toyoda I, et al. Usefulness of 4D-CT for radiation treatment planning of gastric MZBCL\/MALT. J Radiat Res. 2012;53(2):333\u20137.","journal-title":"J Radiat Res"},{"issue":"4","key":"1263_CR18","doi-asserted-by":"publisher","first-page":"239","DOI":"10.3857\/roj.2013.31.4.239","volume":"31","author":"HY Lee","year":"2013","unstructured":"Lee HY, Chang JS, Lee IJ, et al. The deep inspiration breath hold technique using Abches reduces cardiac dose in patients undergoing left-sided breast irradiation. Radiat Oncol J. 2013;31(4):239\u201346.","journal-title":"Radiat Oncol J."},{"key":"1263_CR19","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/1748-717X-5-65","volume":"5","author":"Y Gong","year":"2010","unstructured":"Gong Y, Wang S, Zhou L, et al. Dosimetric comparison using different multileaf collimeters in intensity-modulated radiotherapy for upper thoracic esophageal cancer. Radiat Oncol. 2010;5:65.","journal-title":"Radiat Oncol"},{"issue":"2","key":"1263_CR20","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.ijrobp.2005.09.028","volume":"64","author":"L Feuvret","year":"2006","unstructured":"Feuvret L, Noel G, Mazeron JJ, et al. Conformity index: a review. Int J Radiat Oncol Biol Phys. 2006;64(2):333\u201342.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"6","key":"1263_CR21","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.rpor.2017.08.001","volume":"22","author":"S Clarke","year":"2017","unstructured":"Clarke S, Goodworth J, Westhuyzen J, et al. Software-based evaluation of a class solution for prostate IMRT planning. Rep Pract Oncol Radiother. 2017;22(6):441\u20139.","journal-title":"Rep Pract Oncol Radiother"},{"issue":"5","key":"1263_CR22","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1002\/acm2.12165","volume":"18","author":"DV Fried","year":"2017","unstructured":"Fried DV, Chera BS, Das SK. Assessment of PlanIQ feasibility DVH for head and neck treatment planning. J Appl Clin Med Phys. 2017;18(5):245\u201350.","journal-title":"J Appl Clin Med Phys"},{"issue":"2","key":"1263_CR23","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/j.ijrobp.2016.01.027","volume":"95","author":"X Liu","year":"2016","unstructured":"Liu X, Fang H, Tian Y, et al. Intensity modulated radiation therapy for early-stage primary gastric diffuse large B-cell lymphoma: Dosimetric analysis, clinical outcome, and quality of life. Int J Radiat Oncol Biol Phys. 2016;95(2):712\u201320.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"1263_CR24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.ijrobp.2015.01.009","volume":"92","author":"J Yahalom","year":"2015","unstructured":"Yahalom J, Illidge T, Specht L, et al. Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the international lymphoma radiation oncology group. Int J Radiat Oncol Biol Phys. 2015;92(1):11\u201331.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"1263_CR25","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1007\/s00066-016-0949-0","volume":"192","author":"G Reinartz","year":"2016","unstructured":"Reinartz G, Haverkamp U, Wullenkord R, et al. 4D-Listmode-PET-CT and 4D-CT for optimizing PTV margins in gastric lymphoma : determination of intra- and interfractional gastric motion. Strahlenther Onkol. 2016;192(5):322\u201332.","journal-title":"Strahlenther Onkol"},{"issue":"1","key":"1263_CR26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.radonc.2012.10.016","volume":"106","author":"HD Nissen","year":"2013","unstructured":"Nissen HD, Appelt AL. Improved heart, lung and target dose with deep inspiration breath hold in a large clinical series of breast cancer patients. Radiother Oncol. 2013;106(1):28\u201332.","journal-title":"Radiother Oncol"},{"issue":"5","key":"1263_CR27","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1016\/j.ijrobp.2009.10.006","volume":"78","author":"GR Borst","year":"2010","unstructured":"Borst GR, Sonke JJ, den Hollander S, et al. Clinical results of image-guided deep inspiration breath hold breast irradiation. Int J Radiat Oncol Biol Phys. 2010;78(5):1345\u201351.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"3","key":"1263_CR28","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/S0360-3016(03)00010-5","volume":"56","author":"VM Remouchamps","year":"2003","unstructured":"Remouchamps VM, Letts N, Vicini FA, et al. Initial clinical experience with moderate deep-inspiration breath hold using an active breathing control device in the treatment of patients with left-sided breast cancer using external beam radiation therapy. Int J Radiat Oncol Biol Phys. 2003;56(3):704\u201315.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"1263_CR29","doi-asserted-by":"publisher","first-page":"883","DOI":"10.21873\/anticanres.11394","volume":"37","author":"G Lawler","year":"2017","unstructured":"Lawler G, Leech M. Dose sparing potential of deep inspiration breath-hold technique for left breast Cancer radiotherapy organs-at-risk. Anticancer Res. 2017;37(2):883\u201390.","journal-title":"Anticancer Res"},{"issue":"1","key":"1263_CR30","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.ijrobp.2015.01.013","volume":"92","author":"MC Aznar","year":"2015","unstructured":"Aznar MC, Maraldo MV, Schut DA, et al. Minimizing late effects for patients with mediastinal Hodgkin lymphoma: deep inspiration breath-hold, IMRT, or both? Int J Radiat Oncol Biol Phys. 2015;92(1):169\u201374.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"1263_CR31","doi-asserted-by":"publisher","first-page":"1522","DOI":"10.1016\/j.ijrobp.2011.05.015","volume":"82","author":"A Paumier","year":"2012","unstructured":"Paumier A, Ghalibafian M, Gilmore J, et al. Dosimetric benefits of intensity-modulated radiotherapy combined with the deep-inspiration breath-hold technique in patients with mediastinal Hodgkin's lymphoma. Int J Radiat Oncol Biol Phys. 2012;82(4):1522\u20137.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"1263_CR32","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.ijrobp.2010.09.007","volume":"80","author":"A Paumier","year":"2011","unstructured":"Paumier A, Ghalibafian M, Beaudre A, et al. Involved-node radiotherapy and modern radiation treatment techniques in patients with Hodgkin lymphoma. Int J Radiat Oncol Biol Phys. 2011;80(1):199\u2013205.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"1263_CR33","doi-asserted-by":"publisher","first-page":"60","DOI":"10.3109\/0284186X.2014.932435","volume":"54","author":"PM Petersen","year":"2015","unstructured":"Petersen PM, Aznar MC, Berthelsen AK, et al. Prospective phase II trial of image-guided radiotherapy in Hodgkin lymphoma: benefit of deep inspiration breath-hold. Acta Oncol. 2015;54(1):60\u20136.","journal-title":"Acta Oncol"},{"issue":"6","key":"1263_CR34","doi-asserted-by":"publisher","first-page":"e471","DOI":"10.1016\/j.prro.2017.03.001","volume":"7","author":"H Wang","year":"2017","unstructured":"Wang H, Milgrom SA, Dabaja BS, et al. Daily CT guidance improves target coverage during definitive radiation therapy for gastric MALT lymphoma. Pract Radiat Oncol. 2017;7(6):e471\u2013e8.","journal-title":"Pract Radiat Oncol"},{"issue":"1","key":"1263_CR35","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/j.ijrobp.2004.08.048","volume":"62","author":"KA Goodman","year":"2005","unstructured":"Goodman KA, Toner S, Hunt M, et al. Intensity-modulated radiotherapy for lymphoma involving the mediastinum. Int J Radiat Oncol Biol Phys. 2005;62(1):198\u2013206.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"1263_CR36","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.radonc.2015.10.022","volume":"118","author":"RR Parikh","year":"2016","unstructured":"Parikh RR, Grossbard ML, Harrison LB, et al. Association of intensity-modulated radiation therapy on overall survival for patients with Hodgkin lymphoma. Radiother Oncol. 2016;118(1):52\u20139.","journal-title":"Radiother Oncol"},{"key":"1263_CR37","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/1748-717X-9-94","volume":"9","author":"KR Voong","year":"2014","unstructured":"Voong KR, McSpadden K, Pinnix CC, et al. Dosimetric advantages of a \u201cbutterfly\u201d technique for intensity-modulated radiation therapy for young female patients with mediastinal Hodgkin's lymphoma. Radiat Oncol. 2014;9:94.","journal-title":"Radiat Oncol"},{"issue":"1","key":"1263_CR38","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.ijrobp.2014.01.006","volume":"89","author":"T Illidge","year":"2014","unstructured":"Illidge T, Specht L, Yahalom J, et al. Modern radiation therapy for nodal non-Hodgkin lymphoma-target definition and dose guidelines from the international lymphoma radiation oncology group. Int J Radiat Oncol Biol Phys. 2014;89(1):49\u201358.","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13014-019-1263-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13014-019-1263-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13014-019-1263-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T23:19:45Z","timestamp":1586215185000},"score":1,"resource":{"primary":{"URL":"https:\/\/ro-journal.biomedcentral.com\/articles\/10.1186\/s13014-019-1263-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,8]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["1263"],"URL":"https:\/\/doi.org\/10.1186\/s13014-019-1263-7","relation":{},"ISSN":["1748-717X"],"issn-type":[{"value":"1748-717X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,8]]},"assertion":[{"value":"30 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by Institutional review board (IRB) of Yonsei University Health System (4\u20132017-1035). The patient records\/information was anonymized and de-identified prior to analysis, and informed consent was not obtained from each participants.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"59"}}