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This self-controlled study aimed to find the correlations between dosimetric parameters and RICS.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Totally 49 NPC patients treated with intensity-modulated radiotherapy from May 2010 to Aug. 2013 and diagnosed with RICS during follow-up were enrolled into this study. Minimum point dose, maximum point dose, mean dose (Dmean), dose covering \u226533% volume (D33), dose covering \u226566% volume (D66), and volume receiving \u226560\u2009Gy (V60) were compared between the nasal cavities with and without RICS, through paired t-test. The parameters with difference would enter receiver operating characteristic analysis to determine their cutoff values. Then predicting abilities of the cutoff values were tested by Chi-square test.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Result<\/jats:title>\n<jats:p>The nasal cavities with RICS appeared to have higher Dmean, D33, D66 and V60, compared with those without RICS (<jats:italic>P<\/jats:italic> values were 0.014, 0.003, 0.006 and 0.010). Dmean \u226554.22\u2009Gy, D33\u2009\u2265\u200961.96\u2009Gy, D66\u2009\u2265\u200946.50\u2009Gy and V60\u2009\u2265\u200948.13% were demonstrated to be related with a higher risk of RICS.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Dmean, D33, D66 and V60 of nasal cavity might be used as predictors of RICS. Their values needed to be controlled whenever possible, for ameliorating life quality of NPC patients.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s13014-020-01512-8","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T12:02:43Z","timestamp":1591358563000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dosimetric parameters predict radiation-induced choanal stenosis in patients with nasopharyngeal carcinoma"],"prefix":"10.1186","volume":"15","author":[{"given":"Hui","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-lan","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-jun","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-hong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,5]]},"reference":[{"issue":"10192","key":"1512_CR1","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","volume":"394","author":"YP Chen","year":"2019","unstructured":"Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J. 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