{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T11:57:31Z","timestamp":1787054251131,"version":"build-2736575974"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orthop Surg Res"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>This study evaluated the biomechanical changes in the adjacent vertebrae under a physiological load (500\u2009N) when the clinically relevant amount of bone cement was injected into fractured cadaver vertebral bodies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The embalmed cadaver thoracolumbar specimens in which each vertebral body (T12\u2013L2) had a BMD of &lt; 0.75\u2009g\/cm<jats:sup>2<\/jats:sup> were used for the experiment. For establishing a fracture model, the upper one third of the L1 vertebra was performed wedge osteotomy and the superior endplate was kept complete. Stiffness of specimens was measured in different states. Strain of the adjacent vertebral body and intervertebral disc were measured in pre-fracture, post-fracture, and after augmentation by non-contact optical strain measurement system.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The average amount of bone cement was 4.4\u2009ml (3.8\u20135.0\u2009ml). The stiffness of after augmentation was significantly higher than the stiffness of post-fracture (<jats:italic>p<\/jats:italic> &lt; 0.05), but still lower than pre-fracture stiffness (<jats:italic>p<\/jats:italic> &lt; 0.05). After augmentation, the adjacent upper vertebral strain showed no significant difference (<jats:italic>p<\/jats:italic> &gt; 0.05) with pre-fracture, while the strain of adjacent lower vertebral body was significantly higher than that before fracture (<jats:italic>p<\/jats:italic> &lt; 0.05). In flexion, T12\/L1 intervertebral disc strain was significantly greater after augmentation than after the fracture (<jats:italic>p<\/jats:italic> &lt; 0.05), but there was no significant difference from that before the fracture (<jats:italic>p<\/jats:italic> &gt; 0.05); L1\/2 vertebral strain after augmentation was significantly less than that after the fracture (<jats:italic>p<\/jats:italic> &lt; 0.05), but there was no significant difference from that before the fracture (<jats:italic>p<\/jats:italic> &gt; 0.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>PVP may therefore have partially reversed the abnormal strain state of adjacent vertebral bodies which was caused by fracture.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13018-020-01906-0","type":"journal-article","created":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T10:03:10Z","timestamp":1598868190000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["How the clinical dosage of bone cement biomechanically affects adjacent vertebrae"],"prefix":"10.1186","volume":"15","author":[{"given":"Xu-shi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-ming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-dong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-fei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6701-7486","authenticated-orcid":false,"given":"Hai-long","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,31]]},"reference":[{"issue":"1","key":"1906_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1148\/radiol.2261011911","volume":"226","author":"AA Uppin","year":"2003","unstructured":"Uppin AA, Hirsch JA, Centenera LV, Pfiefer BA, Pazianos AG, Choi IS. 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Not applicable. The co-authors consented to the publication of this is article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"370"}}