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We presented a simple skin stretching system and negative pressure wound therapy for the repair of complex diabetic foot wounds to examine the effectiveness and safety.<\/jats:p>\n                  <jats:p>\n                    A total of 16 patients with diabetic foot ulcers were retrospectively reviewed between January 2015 and October 2020. All patients underwent the treatment by 3 stages. In stage 2, these difficult-to-close wounds of diabetes foot were residual. This method was applied to the wounds with a median defect size of 20.42 cm\n                    <jats:sup>2<\/jats:sup>\n                    (range, 4.71\u201366.76 cm\n                    <jats:sup>2<\/jats:sup>\n                    ).\n                  <\/jats:p>\n                  <jats:p>\n                    The median time for closure of complex diabetic foot wounds was 14 days ranging from 8 to 19 days. With respect to the absolute rates of reduction, it was observed with a median of 1.86 cm\n                    <jats:sup>2<\/jats:sup>\n                    \/day, ranging from 0.29 cm\n                    <jats:sup>2<\/jats:sup>\n                    \/day to 8.35 cm\n                    <jats:sup>2<\/jats:sup>\n                    \/day. In accordance with the localization of the defect, the patients were divided into 3 groups: side of the foot (37.5%), dorsum of the foot (50.0%), and others (12.5%). There was no statistical difference between side of the foot and dorsum of the foot in terms of the median defect size with\n                    <jats:italic>P<\/jats:italic>\n                    = 0.069 (Kruskal\u2013Wallis test). Otherwise, there were statistically significant differences regarding the median time and the median absolute rates (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05; Kruskal\u2013Wallis test). No severe complications were encountered in this study.\n                  <\/jats:p>\n                  <jats:p>In summary, our results show that application of the simple skin stretching system and NPWT is an effective and safe approach to complex diabetic foot wounds. Nevertheless, more attention should be paid to the appropriate patient selection and intraoperative judgment to ensure wound closure and avoid undue complications.<\/jats:p>","DOI":"10.1186\/s13018-021-02405-6","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T07:03:37Z","timestamp":1618383817000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Application of a simple skin stretching system and negative pressure wound therapy in repair of complex diabetic foot wounds"],"prefix":"10.1186","volume":"16","author":[{"given":"Yaojun","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4946-0000","authenticated-orcid":false,"given":"Liang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaokun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingnan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiejie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingjiang","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"key":"2405_CR1","volume-title":"IDF diabetes atlas","author":"International Diabetes Federation","year":"2017","unstructured":"International Diabetes Federation. 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All patients signed written consent forms.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication using the opt-out form on the website.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"258"}}