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Nevertheless, the correlation between the combined use of GNRI and SII metrics and hip fractures has yet to be elucidated. This study aimed to determine whether the amalgamation of SII and GNRI scores constitutes an independent prognostic factor for elderly patients with hip fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of elderly patients admitted to our facility with hip fractures, encompassing both femoral neck and intertrochanteric fractures. Demographic information, experimental parameters, and postoperative complications were systematically recorded. The Geriatric Nutritional Risk Index (GNRI) and Systemic Immunoinflammatory Index (SII) were meticulously computed. Receiver operating characteristic\u00a0(ROC) curves were generated, and optimal cutoff values for each parameter were determined. Subsequently, a multivariate Cox regression analysis was employed to assess the predictive utility of the SII\u2013GNRI score in relation to 1-year postoperative mortality among elderly patients with hip fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In a study involving 597 patients, 90 of whom experienced mortality within 1 year, it was observed that the SII-GNRI score in the group of patients who passed away was significantly higher compared to the group that survived. Following a multifactorial adjustment, it was established that a high SII\u2013GNRI score served as an independent predictor of 1-year all-cause mortality in older patients with hip fractures. In addition to the SII\u2013GNRI score, factors such as length of hospital stay, CCI\u2009&gt;\u20092, and\u00a0blood transfusion were also identified as independent risk factors for survival. Notably, the incidence of postoperative complications in patients with high SII\u2013GNRI scores was significantly greater than in patients with low scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The SII\u2013GNRI score proves valuable in predicting the 1-year survival rate for elderly patients with hip fractures who have undergone surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13018-024-04585-3","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T03:02:37Z","timestamp":1707188557000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Combined Systemic Immune-inflammatory Index (SII) and Geriatric Nutritional Risk\u00a0Index (GNRI) predict survival in elderly patients with hip fractures: a retrospective study"],"prefix":"10.1186","volume":"19","author":[{"given":"Ling","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianjie","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhua","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"4585_CR1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2018.378","author":"CS Kim","year":"2021","unstructured":"Kim CS, Han KD, Jung JH, Choi HS, Bae EH, Ma SK, et al. 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