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A novel ULBD approach, called \u2018Non-touch Over-Top\u2019 technique, was utilized in this study. We compared preoperative and postoperative metrics such as demographic data, Visual Analogue Scale (VAS) for pain, Oswestry Disability Index (ODI), Japanese Orthopedic Association (JOA) score, surgical details, and radiographic changes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The average follow-up duration was 14.41\u2009\u00b1\u20092.86\u00a0months. Notable improvements were observed postoperatively in VAS scores for back and leg pain (from 5.56\u2009\u00b1\u20090.20 and 6.95\u2009\u00b1\u20090.24 to 0.20\u2009\u00b1\u20090.06 and 0.12\u2009\u00b1\u20090.05), ODI (from 58.68\u2009\u00b1\u20090.80% to 8.10\u2009\u00b1\u20090.49%), and JOA scores (from 9.37\u2009\u00b1\u20090.37 to 25.07\u2009\u00b1\u20090.38). Radiographic measurements showed significant improvements in lumbar and segmental lordosis angles, disc height, and spinal canal area. A high fusion rate (97.56% at 6\u00a0months, 100% at 12\u00a0months) and a low cage subsidence rate (2.44%) were noted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>PE-PLIF combined with the novel ULBD technique via a large-channel endoscope offers significant short-term benefits for LDD management. The procedure effectively expands spinal canal volume, decompresses nerve structures, improves lumbar alignment, and stabilizes the spine. Notably, it improves patients' quality of life and minimizes complications, highlighting its potential as a promising LDD treatment option.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13018-024-04755-3","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T07:02:32Z","timestamp":1714374152000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of PE-PLIF with a novel ULBD approach for lumbar degeneration diseases: a large-channel endoscopic retrospective study"],"prefix":"10.1186","volume":"19","author":[{"given":"Yichi","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuankun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingbo","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowen","family":"Kou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weizhi","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengcheng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shishuang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weijun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"key":"4755_CR1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.16082.1","author":"C Bagley","year":"2019","unstructured":"Bagley C, et al. 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