{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T04:01:52Z","timestamp":1791518512252,"version":"4.3.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orthop Surg Res"],"DOI":"10.1186\/s13018-024-04997-1","type":"journal-article","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:02:43Z","timestamp":1724457763000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Analysis of the predictive value of microRNA-199b-5p combined with nitric oxide for venous thrombosis in patients undergoing total knee arthroplasty"],"prefix":"10.1186","volume":"19","author":[{"given":"Shen","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenyi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,24]]},"reference":[{"issue":"1","key":"4997_CR1","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1093\/bmb\/ldac012","volume":"142","author":"G Gargano","year":"2022","unstructured":"Gargano G, Oliva F, Oliviero A, Maffulli N. Small interfering RNAs in the management of human rheumatoid arthritis. Br Med Bull. 2022;142(1):34\u201343.","journal-title":"Br Med Bull"},{"issue":"1","key":"4997_CR2","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1093\/bmb\/ldad023","volume":"148","author":"G Gargano","year":"2023","unstructured":"Gargano G, Asparago G, Spiezia F, Oliva F, Maffulli N. Small interfering RNAs in the management of human osteoporosis. Br Med Bull. 2023;148(1):58\u201369.","journal-title":"Br Med Bull"},{"key":"4997_CR3","doi-asserted-by":"crossref","unstructured":"Zhao Z, Wang C, Xu Y, Wang X, Jia B, Yu T et al. Effects of the local bone renin-angiotensin system on Titanium-Particle-Induced Periprosthetic Osteolysis. Front Pharmacol. 2021; 12684375.","DOI":"10.3389\/fphar.2021.684375"},{"key":"4997_CR4","doi-asserted-by":"crossref","unstructured":"Yan J, Zhou J, Zhen J, Li L, Care Clinical Research Group ZPC. Knowledge and awareness of venous thromboembolism in Intensive Care Units in Zhejiang Province, China: a cross-sectional survey. Med Sci Monit. 2020; 26e923378.","DOI":"10.12659\/MSM.923378"},{"issue":"1","key":"4997_CR5","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1186\/s13018-022-03457-y","volume":"17","author":"X Xiong","year":"2022","unstructured":"Xiong X, Xu S, Li T, Cheng B. Correlation of the severity of anemia in patients undergoing total joint arthroplasty with preoperative deep vein thrombosis: a retrospective cohort study. J Orthop Surg Res. 2022;17(1):554.","journal-title":"J Orthop Surg Res"},{"key":"4997_CR6","doi-asserted-by":"crossref","unstructured":"Li Q, Dai B, Yao Y, Song K, Chen D, Jiang Q. Chronic kidney dysfunction can increase the risk of deep vein thrombosis after total hip and knee arthroplasty. Biomed Res Int. 2017; 20178260487.","DOI":"10.1155\/2017\/8260487"},{"issue":"1","key":"4997_CR7","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1186\/s13287-022-02924-x","volume":"13","author":"S Hamad","year":"2022","unstructured":"Hamad S, Derichsweiler D, Gaspar JA, Brockmeier K, Hescheler J, Sachinidis A, et al. High-efficient serum-free differentiation of endothelial cells from human iPS cells. Stem Cell Res Ther. 2022;13(1):251.","journal-title":"Stem Cell Res Ther"},{"key":"4997_CR8","doi-asserted-by":"crossref","unstructured":"El Hasbani G, Taher AT, Jawad A, Uthman I. COVID-19, Antiphospholipid Antibodies, and Catastrophic Antiphospholipid Syndrome: a possible association? Clin Med Insights Arthritis Musculoskelet Disord. 2020; 131179544120978667.","DOI":"10.1177\/1179544120978667"},{"issue":"SupplSuppl","key":"4997_CR9","doi-asserted-by":"publisher","first-page":"S66","DOI":"10.1016\/j.placenta.2009.12.021","volume":"31","author":"L Myatt","year":"2010","unstructured":"Myatt L, Review. Reactive oxygen and nitrogen species and functional adaptation of the placenta. Placenta. 2010;31(SupplSuppl):S66\u20139.","journal-title":"Placenta"},{"key":"4997_CR10","doi-asserted-by":"crossref","unstructured":"Meng P, Yang R, Jiang F, Guo J, Lu X, Yang T et al. Molecular mechanism of Astragaloside IV in improving endothelial dysfunction of Cardiovascular diseases mediated by oxidative stress. Oxid Med Cell Longev. 2021; 20211481236.","DOI":"10.1155\/2021\/1481236"},{"issue":"1","key":"4997_CR11","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1093\/bmb\/ldz015","volume":"130","author":"A Oliviero","year":"2019","unstructured":"Oliviero A, Della Porta G, Peretti GM, Maffulli N. MicroRNA in osteoarthritis: physiopathology, diagnosis and therapeutic challenge. Br Med Bull. 2019;130(1):137\u201347.","journal-title":"Br Med Bull"},{"issue":"1","key":"4997_CR12","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1093\/bmb\/ldaa002","volume":"133","author":"L Giordano","year":"2020","unstructured":"Giordano L, Porta GD, Peretti GM, Maffulli N. Therapeutic potential of microRNA in tendon injuries. Br Med Bull. 2020;133(1):79\u201394.","journal-title":"Br Med Bull"},{"issue":"1","key":"4997_CR13","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1093\/bmb\/ldaa040","volume":"138","author":"G Gargano","year":"2021","unstructured":"Gargano G, Oliviero A, Oliva F, Maffulli N. Small interfering RNAs in tendon homeostasis. Br Med Bull. 2021;138(1):58\u201367.","journal-title":"Br Med Bull"},{"issue":"3","key":"4997_CR14","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.3892\/etm.2016.3546","volume":"12","author":"X Xie","year":"2016","unstructured":"Xie X, Liu C, Lin W, Zhan B, Dong C, Song Z, et al. Deep vein thrombosis is accurately predicted by comprehensive analysis of the levels of microRNA-96 and plasma D-dimer. Exp Ther Med. 2016;12(3):1896\u2013900.","journal-title":"Exp Ther Med"},{"key":"4997_CR15","doi-asserted-by":"crossref","unstructured":"Lin X, Qiu W, Xiao Y, Ma J, Xu F, Zhang K et al. MiR-199b-5p suppresses Tumor Angiogenesis mediated by vascular endothelial cells in breast Cancer by targeting ALK1. Front Genet. 2019; 101397.","DOI":"10.3389\/fgene.2019.01397"},{"key":"4997_CR16","doi-asserted-by":"crossref","unstructured":"Chen S, Wu H, Zhu L, Jiang M, Wei S, Luo J et al. MiR-199b-5p promotes gastric Cancer Progression by regulating HHIP expression. Front Oncol. 2021; 11728393.","DOI":"10.3389\/fonc.2021.728393"},{"key":"4997_CR17","doi-asserted-by":"crossref","unstructured":"Feng T, Zhang Q, Li SH, Ping YL, Tian MQ, Zhou SH et al. Inhibition of miR-199b-5p reduces pathological alterations in osteoarthritis by potentially targeting Fzd6 and Gcnt2. Elife. 2024; 12.","DOI":"10.7554\/eLife.92645"},{"issue":"4","key":"4997_CR18","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1049\/syb2.12071","volume":"17","author":"Q Wang","year":"2023","unstructured":"Wang Q, Chang Y, Yang X, Han Z. Deep sequencing of circulating miRNAs and target mRNAs level in deep venous thrombosis patients. IET Syst Biol. 2023;17(4):212\u201327.","journal-title":"IET Syst Biol"},{"issue":"6","key":"4997_CR19","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1097\/HCO.0000000000000443","volume":"32","author":"KA Lee","year":"2017","unstructured":"Lee KA, Ramaswamy RS. Interventional approaches to deep venous thrombosis. Curr Opin Cardiol. 2017;32(6):679\u201386.","journal-title":"Curr Opin Cardiol"},{"issue":"1","key":"4997_CR20","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s11239-015-1308-1","volume":"41","author":"W Ageno","year":"2016","unstructured":"Ageno W, Beyer-Westendorf J, Garcia DA, Lazo-Langner A, McBane RD, Paciaroni M. Guidance for the management of venous thrombosis in unusual sites. J Thromb Thrombolysis. 2016;41(1):129\u201343.","journal-title":"J Thromb Thrombolysis"},{"issue":"2","key":"4997_CR21","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1097\/TA.0b013e318241090d","volume":"72","author":"BR Moed","year":"2012","unstructured":"Moed BR, Miller JR, Tabaie SA. Sequential duplex ultrasound screening for proximal deep venous thrombosis in asymptomatic patients with acetabular and pelvic fractures treated operatively. J Trauma Acute Care Surg. 2012;72(2):443\u20137.","journal-title":"J Trauma Acute Care Surg"},{"issue":"5","key":"4997_CR22","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1016\/j.thromres.2007.12.026","volume":"122","author":"S Noboa","year":"2008","unstructured":"Noboa S, Le Gal G, Lacut K, Mercier B, Leroyer C, Nowak E, et al. Family history as a risk factor for venous thromboembolism. Thromb Res. 2008;122(5):624\u20139.","journal-title":"Thromb Res"},{"key":"4997_CR23","doi-asserted-by":"crossref","unstructured":"Kiang JG, Olabisi AO. Radiation: a poly-traumatic hit leading to multi-organ injury. Cell Biosci. 2019; 925.","DOI":"10.1186\/s13578-019-0286-y"},{"issue":"1","key":"4997_CR24","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1038\/s41598-018-37130-4","volume":"9","author":"J Wang","year":"2019","unstructured":"Wang J, Niu N, Xu S, Jin ZG. A simple protocol for isolating mouse lung endothelial cells. Sci Rep. 2019;9(1):1458.","journal-title":"Sci Rep"},{"issue":"1","key":"4997_CR25","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s41232-021-00186-3","volume":"42","author":"Y Yoshimatsu","year":"2022","unstructured":"Yoshimatsu Y, Watabe T. Emerging roles of inflammation-mediated endothelial-mesenchymal transition in health and disease. Inflamm Regen. 2022;42(1):9.","journal-title":"Inflamm Regen"},{"issue":"17","key":"4997_CR26","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.21037\/atm-20-5828","volume":"8","author":"X Yang","year":"2020","unstructured":"Yang X, Xiang Y, Wang F, Cai G, Li Y, Zhong L, et al. Expressions and relationship of Kruppel-like factor 15 and endothelial nitric oxide synthase in experimental deep venous thrombosis. Ann Transl Med. 2020;8(17):1090.","journal-title":"Ann Transl Med"},{"key":"4997_CR27","doi-asserted-by":"crossref","unstructured":"Favreau AJ, McGlauflin RE, Duarte CW, Sathyanarayana P. miR-199b, a novel tumor suppressor miRNA in acute myeloid leukemia with prognostic implications. Exp Hematol Oncol. 2015; 54.","DOI":"10.1186\/s40164-016-0033-6"},{"issue":"2","key":"4997_CR28","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/bjc.2017.164","volume":"117","author":"SJ Zhou","year":"2017","unstructured":"Zhou SJ, Liu FY, Zhang AH, Liang HF, Wang Y, Ma R, et al. MicroRNA-199b-5p attenuates TGF-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma. Br J Cancer. 2017;117(2):233\u201344.","journal-title":"Br J Cancer"},{"key":"4997_CR29","doi-asserted-by":"crossref","unstructured":"Lu J, Fang Q, Ge X. Role and mechanism of mir-5189-3p in deep vein thrombosis of Lower extremities. Ann Vasc Surg. 2021; 77288\u201395.","DOI":"10.1016\/j.avsg.2021.07.004"}],"container-title":["Journal of Orthopaedic Surgery and Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13018-024-04997-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13018-024-04997-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13018-024-04997-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:07:19Z","timestamp":1724458039000},"score":1,"resource":{"primary":{"URL":"https:\/\/josr-online.biomedcentral.com\/articles\/10.1186\/s13018-024-04997-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,24]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4997"],"URL":"https:\/\/doi.org\/10.1186\/s13018-024-04997-1","relation":{},"ISSN":["1749-799X"],"issn-type":[{"value":"1749-799X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,24]]},"assertion":[{"value":"21 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Affiliated Hospital of Panzhihua University before the study began. The participants\u2019 right to be informed about the study was ensured and agreed to participate in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"505"}}