{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:45:27Z","timestamp":1791913527814,"version":"4.3.4"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orthop Surg Res"],"DOI":"10.1186\/s13018-024-05417-0","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T17:32:26Z","timestamp":1736530346000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Patient-specific spine digital twins: a computational characterization of the idiopathic scoliosis"],"prefix":"10.1186","volume":"20","author":[{"given":"David","family":"Landinez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Francisco","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Cifuentes De la Portilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,10]]},"reference":[{"key":"5417_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-017-9445-0","author":"PJ York","year":"2017","unstructured":"York PJ, Kim HJ. Degenerative scoliosis. Curr Rev Mosculoskelet Med. 2017. https:\/\/doi.org\/10.1007\/s12178-017-9445-0.","journal-title":"Curr Rev Mosculoskelet Med."},{"key":"5417_CR2","first-page":"257","volume":"3","author":"S Kotwal","year":"2011","unstructured":"Kotwal S, Pumberger M, Hughes A, Girardi F. Degenerative scoliosis: a review. Hosp Sp Surg J. 2011;3:257.","journal-title":"Hosp Sp Surg J."},{"key":"5417_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13013-017-0114-2","volume":"12","author":"M Rigo","year":"2017","unstructured":"Rigo M, Jela\u010di\u0107 M. Brace technology thematic series: the 3d rigo ch\u00eaneau-type brace. Scoliosis Spinal Disord. 2017;12:1\u201346.","journal-title":"Scoliosis Spinal Disord."},{"key":"5417_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1748-7161-5-1","volume":"5","author":"MD Rigo","year":"2010","unstructured":"Rigo MD, Villagrasa M, Gallo D. A specific scoliosis classification correlating with brace treatment: description and reliability. Scoliosis. 2010;5:1\u201311.","journal-title":"Scoliosis"},{"key":"5417_CR5","volume-title":"Complicaciones perioperatorias en el manejo de correcci\u00f3n de escoliosis en un hospital de tercer nivel en la ciudad de bogot\u00e1 entre el 2010\u20132014","author":"MC Silva","year":"2016","unstructured":"Silva MC, Ospina MC. Complicaciones perioperatorias en el manejo de correcci\u00f3n de escoliosis en un hospital de tercer nivel en la ciudad de bogot\u00e1 entre el 2010\u20132014. Medellin: Facultad de Medicina: Universidad CES; 2016."},{"key":"5417_CR6","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1016\/j.clinbiomech.2007.07.008","volume":"22","author":"H Schmidt","year":"2007","unstructured":"Schmidt H, Kettler A, Rohlmann A, Claes L, Wilke H-J. The risk of disc prolapses with complex loading in different degrees of disc degeneration-a finite element analysis. Clin Biomech. 2007;22:988\u201398.","journal-title":"Clin Biomech"},{"key":"5417_CR7","first-page":"61","volume":"3","author":"M Luchtmann","year":"2016","unstructured":"Luchtmann M, Firsching R. Lumbar disc herniation: evidence-based guidelines-a review. Indian Practitioner. 2016;3:61.","journal-title":"Indian Practitioner."},{"key":"5417_CR8","doi-asserted-by":"publisher","DOI":"10.23937\/2643-4016\/1710030","author":"T Eneqvist","year":"2023","unstructured":"Eneqvist T, Alexanderson K, Lapidus LJ. Surgery for lumbar disc herniation and future risk for long-term sick leave: a two-year prospective Swedish cohort study of 5842 patients of working age. Int Arch Othop Surg. 2023. https:\/\/doi.org\/10.23937\/2643-4016\/1710030.","journal-title":"Int Arch Othop Surg."},{"key":"5417_CR9","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1299\/jbse.3.399","volume":"3","author":"T Aoyama","year":"2008","unstructured":"Aoyama T, Azegami H, Kawakami N. Nonlinear buckling analysis for etiological study of idiopathic scoliosis. J Biomech Sci Eng. 2008;3:399\u2013410.","journal-title":"J Biomech Sci Eng."},{"key":"5417_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-005-1029-9","author":"HJ Wilke","year":"2005","unstructured":"Wilke HJ, et al. Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part I lumbar spine. Eur Spine J. 2005. https:\/\/doi.org\/10.1007\/s00586-005-1029-9.","journal-title":"Eur Spine J."},{"key":"5417_CR11","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s43390-022-00636-z","volume":"11","author":"CR D\u2019Andrea","year":"2023","unstructured":"D\u2019Andrea CR, Samdani AF, Balasubramanian S. Patient-specific finite element modeling of scoliotic curve progression using region-specific stress-modulated vertebral growth. Spine Deform. 2023;11:525.","journal-title":"Spine Deform."},{"issue":"2","key":"5417_CR12","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1111\/os.13572","volume":"15","author":"L Jiahao","year":"2023","unstructured":"Jiahao L, et al. Construction of the adjusted scoliosis 3D finite element model and biomechanical analysis under gravity. Orthop Surg. 2023;15(2):606.","journal-title":"Orthop Surg."},{"key":"5417_CR13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13018-014-0138-8","volume":"10","author":"J Zheng","year":"2015","unstructured":"Zheng J, Yang Y, Lou S, Zhang D, Liao S. Construction and validation of a three-dimensional finite element model of degenerative scoliosis. Orthop Surg. 2015;10:1\u20137.","journal-title":"Orthop Surg."},{"key":"5417_CR14","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s00586-003-0586-z","volume":"13","author":"S Tan","year":"2004","unstructured":"Tan S, Teo E, Chua H. Quantitative three-dimensional anatomy of cervical, thoracic and lumbar vertebrae of Chinese Singaporeans. Eur Spine J. 2004;13:137\u201346.","journal-title":"Eur Spine J."},{"key":"5417_CR15","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.spinee.2007.05.001","volume":"8","author":"BP Yang","year":"2008","unstructured":"Yang BP, Chen LA, Ondra SL. A novel mathematical model of the sagittal spine: application to pedicle subtraction osteotomy for correction of fixed sagittal deformity. Spine J. 2008;8:359\u201366.","journal-title":"Spine J."},{"key":"5417_CR16","doi-asserted-by":"publisher","first-page":"317","DOI":"10.31661\/jbpe.v9i3Jun.730","volume":"9","author":"A Safari","year":"2019","unstructured":"Safari A, Parsaei H, Zamani A, Pourabbas B. A semi-automatic algorithm for estimating cobb angle. J Biomed Phys Eng. 2019;9:317.","journal-title":"J Biomed Phys Eng."},{"key":"5417_CR17","first-page":"239","volume":"4","author":"A Vidal-Lesso","year":"2014","unstructured":"Vidal-Lesso A, Ledesma-Orozco E, Daza-Ben\u00edtez L, Lesso-Arroyo R. Mechanical characterization of femoral cartilage under unicompartimental osteoarthritis. Ing Mec Tecnol Desarro. 2014;4:239\u201346.","journal-title":"Ing Mec Tecnol Desarro."},{"key":"5417_CR18","unstructured":"Gzik-Zroska B, Tejszerska D, Wola\u0144ski W, Gzik M. Biomechanical analysis of funnel chest after correction of deformation by stabilizing plate. Silesian University of Technology, Faculty of Mechanical Engineering, Department of Applied Mechanics, Konarskiego 18A, 44-100 Gliwice, Poland 2015."},{"key":"5417_CR19","volume-title":"Vertebrae detection and localization in CT with two-stage CNNS and dense annotations","author":"J McCount","year":"2019","unstructured":"McCount J, Glocker B. Vertebrae detection and localization in CT with two-stage CNNS and dense annotations. London, UK: Department of Computing, Imperial College; 2019."},{"key":"5417_CR20","doi-asserted-by":"crossref","unstructured":"Beaus\u00e9jour MH, Petit Y, Arnoux PJ, Wagnac E. Comparison of two intervertebral disc failure models in a numerical c4-c5 trauma mode. International Laboratory of Spine Imaging and Biomechanics 2019.","DOI":"10.1109\/EMBC.2019.8857095"},{"key":"5417_CR21","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1080\/10255842.2018.1508571","volume":"21","author":"B Schlager","year":"2018","unstructured":"Schlager B, et al. Uncertainty analysis of material properties and morphology parameters in numerical models regarding the motion of lumbar vertebral segments. Comput Methods Biomech Biomed Eng. 2018;21:673\u201383.","journal-title":"Comput Methods Biomech Biomed Eng."},{"key":"5417_CR22","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1016\/j.medengphy.2012.09.009","volume":"35","author":"K-S Han","year":"2013","unstructured":"Han K-S, Rohlmann A, Zander T, Taylor WR. Lumbar spinal loads vary with body height and weight. Med Eng Phys. 2013;35:969\u201377.","journal-title":"Med Eng Phys."},{"key":"5417_CR23","doi-asserted-by":"publisher","first-page":"16916","DOI":"10.1038\/s41598-020-73881-9","volume":"10","author":"S Jia","year":"2020","unstructured":"Jia S, et al. The influence of the rib cage on the static and dynamic stability responses of the scoliotic spine. Scientif Rep. 2020;10:16916.","journal-title":"Scientif Rep."},{"key":"5417_CR24","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3389\/fbioe.2016.00093","volume":"4","author":"JS Coogan","year":"2016","unstructured":"Coogan JS, et al. Finite element study of a lumbar intervertebral disc nucleus replacement device. Front Bioeng Biotechnol. 2016;4:93.","journal-title":"Front Bioeng Biotechnol."},{"key":"5417_CR25","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.jmbbm.2016.01.015","volume":"61","author":"DL Robinson","year":"2016","unstructured":"Robinson DL, et al. Mechanical properties of normal and osteoarthritic human articular cartilage. J Mech Behav Biomed Mater. 2016;61:96\u2013109.","journal-title":"J Mech Behav Biomed Mater."},{"key":"5417_CR26","first-page":"80","volume":"123","author":"TB Grivas","year":"2006","unstructured":"Grivas TB, Vasiliadis E, Malakasis M, Moukasis V, Segos D. Intervertebral disc biomechanics in the pathogenesis of idiopathic scoliosis. Stud Health Technol Inform. 2006;123:80.","journal-title":"Stud Health Technol Inform."}],"container-title":["Journal of Orthopaedic Surgery and Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13018-024-05417-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13018-024-05417-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13018-024-05417-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T20:02:42Z","timestamp":1763409762000},"score":1,"resource":{"primary":{"URL":"https:\/\/josr-online.biomedcentral.com\/articles\/10.1186\/s13018-024-05417-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5417"],"URL":"https:\/\/doi.org\/10.1186\/s13018-024-05417-0","relation":{},"ISSN":["1749-799X"],"issn-type":[{"value":"1749-799X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,10]]},"assertion":[{"value":"17 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 November 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Missing Funding note was added.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no Conflict of interest. No funding declarations. This project has the approval of the ethics committee of the Engineering School of Universidad de los Andes. No patients nor sensitive information was required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"39"}}