{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T09:22:23Z","timestamp":1776417743468,"version":"3.51.2"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The treatment of persistent air leak is a challenge. Herein, we reported the combined intrabronchial and intrapleural injection of fibrin glue using fiber bronchoscopy to seal off an alveolar pleura fistula developed following necrotizing pneumonia in high-risk patient.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 74-year-old man was intubated in emergency for acute ischemic stroke. Percutaneous dilatational tracheostomy was then performed, and 15\u2009days later patient returned to spontaneous breathing. However, he developed alveolar pleural fistula following necrotizing pneumonia with persistent air leaks. The intrabronchial and intrapleural injection of fibrin glue using fiber bronchoscopy sealed off the alveolar pleura fistula after that other endoscopic treatments as bronchial valve and intrabronchial fibrin glue application had failed.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our strategy is safe and easy to reproduce. It represents an additional method in the armamentarium of the physicians for the management of PAL when all standard strategies are unfeasible or fail.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-019-0987-7","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T15:05:17Z","timestamp":1568819117000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Combined intrapleural and intrabronchial injection of fibrin glue for closing alveolar pleural fistula: a case report"],"prefix":"10.1186","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0628-613X","authenticated-orcid":false,"given":"Alfonso","family":"Fiorelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Italia","family":"Odierna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Scarano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Caronia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Failla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Iannotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Santini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Pace","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"issue":"11","key":"987_CR1","doi-asserted-by":"publisher","first-page":"6158","DOI":"10.21037\/jtd.2018.10.61","volume":"10","author":"A Fiorelli","year":"2018","unstructured":"Fiorelli A, D'Andrilli A, Cascone R, Occhiati L, Anile M, Diso D, Cassiano F, Poggi C, Ibrahim M, Cusumano G, Terminella A, Failla G, La Sala A, Bezzi M, Innocenti M, Torricelli E, Venuta F, Rendina EA, Vicidomini G, Santini M, Andreetti C. Unidirectional endobronchial valves for management of persistent air-leaks: results of a multicenter study. J Thorac Dis. 2018;10(11):6158\u201367.","journal-title":"J Thorac Dis."},{"issue":"Suppl 10","key":"987_CR2","doi-asserted-by":"publisher","first-page":"S1034","DOI":"10.21037\/jtd.2017.05.47","volume":"9","author":"S Keshishyan","year":"2017","unstructured":"Keshishyan S, Revelo AE, Epelbaum O. Bronchoscopic management of prolonged air leak. J Thorac Dis. 2017;9(Suppl 10):S1034\u201346.","journal-title":"J Thorac Dis"},{"issue":"1","key":"987_CR3","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ccm.2009.10.002","volume":"31","author":"DE Wood","year":"2010","unstructured":"Wood DE, Cerfolio RJ, Gonzalez X, Springmeyer SC. Bronchoscopic management of prolonged air leak. Clin Chest Med. 2010;31(1):127\u201333.","journal-title":"Clin Chest Med"},{"key":"987_CR4","doi-asserted-by":"publisher","first-page":"S3315","DOI":"10.21037\/jtd.2018.06.69","volume":"10","author":"A Fiorelli","year":"2018","unstructured":"Fiorelli A, D'Andrilli A, Bezzi M, Ibrahim M, Anile M, Diso D, Cusumano G, Terminella A, Luzzi V, Innocenti M, Novali M, Carelli E, Freda C, Natale G, Peritore V, Poggi C, Failla G, Basile M, Mazzucca E, Conforti S, Serra N, Torre M, Venuta F, Rendina EA, Santini M, Andreetti C. Complications related to endoscopic lung volume reduction for emphysema with endobronchial valves: results of a multicenter study. J Thorac Dis. 2018;10(Suppl 27:S3315\u201325.","journal-title":"J Thorac Dis."},{"issue":"3","key":"987_CR5","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1378\/chest.117.3.790","volume":"117","author":"T Kinoshita","year":"2000","unstructured":"Kinoshita T, Miyoshi S, Katoh M, Yoshimasu T, Juri M, Maebeya S, Naito Y. Intrapleural administration of a large amount of diluted fibrin glue for intractable pneumothorax. Chest. 2000;117(3):790\u20135.","journal-title":"Chest"},{"issue":"9","key":"987_CR6","doi-asserted-by":"publisher","first-page":"487","DOI":"10.4103\/1947-2714.141660","volume":"6","author":"P Shrestha","year":"2014","unstructured":"Shrestha P, Safdar SA, Jawad SA, Shaaban H, Dieguez J, Elberaqdar E, Rai S, Adelman M. Successful closure of a bronchopleural fistula by intrapleural administration of fibrin sealant: a case report with review of literature. N Am J Med Sci. 2014;6(9):487\u201390.","journal-title":"N Am J Med Sci"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-019-0987-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13019-019-0987-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-019-0987-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T23:32:19Z","timestamp":1600299139000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-019-0987-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,18]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["987"],"URL":"https:\/\/doi.org\/10.1186\/s13019-019-0987-7","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,18]]},"assertion":[{"value":"21 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 September 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Patient signed an informed consent for the operation and was aware that his data could be used for scientific purpose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Patient was aware that his data could be used for scientific purpose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"171"}}