{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:28:31Z","timestamp":1740144511262,"version":"3.37.3"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T00:00:00Z","timestamp":1622592000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T00:00:00Z","timestamp":1622592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Medizinische Hochschule Hannover (MHH)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Extracorporeal life support (ECLS) is an established tool to stabilize severely ill patients with therapy-refractory hemodynamic or respiratory failure. Recently, we established a mobile ECLS retrieval service at our institution. However, data on the outcome of patients receiving ECLS at outside hospitals for transportation into tertiary hospitals is still sparse.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We have analyzed all patients receiving ECLS in outside hospitals (Transport group, TG) prior to transportation to our institution and compared the outcome to our in-house ECLS experience (Home Group, HG).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Between 2012 and 2018, we performed 978 ECLS implantations, 243 of which were performed on-site in tertiary hospitals for ECLS supported transportation. Significantly more veno-venous systems were implanted in TG (<jats:italic>n<\/jats:italic>\u00a0=\u2009129 (53%) vs. <jats:italic>n<\/jats:italic>\u00a0=\u2009327 (45%), <jats:italic>p<\/jats:italic>\u00a0=\u20090.012). Indication for ECLS support differed between the groups, with more pneumonia; acute respiratory distress syndromes in the TG group and of course, more postcardiotomy patients in HG. Mean age was 47 (\u00b1 20) (HG) vs. 48 (\u00b1 18) (TG) years, <jats:italic>p<\/jats:italic>\u00a0=\u20090.477 with no change over time. No differences were seen in ECLS support time (8.03\u2009days \u00b18.19\u2009days HG vs 7.81\u2009days \u00b16.71\u2009days TG, <jats:italic>p<\/jats:italic>\u00a0=\u20090.675). 30-day mortality (<jats:italic>n<\/jats:italic>\u00a0=\u2009379 (52%) (HG) vs. <jats:italic>n<\/jats:italic>\u00a0=\u2009119 (49%) (TG) <jats:italic>p<\/jats:italic>\u00a0=\u20090.265) and death on ECLS support (<jats:italic>n<\/jats:italic>\u00a0=\u2009322 (44%) (HG) vs. <jats:italic>n<\/jats:italic>\u00a0=\u200997 (40%) TG, <jats:italic>p<\/jats:italic>\u00a0=\u20090.162) were comparable between the two groups, despite a more severe SAVE score in the v-a TG (HG: \u2212\u20091.56 (\u00b1 4.73) vs. TG -3.93 (\u00b1 4.22) <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001). Mortality rates did not change significantly over the years. Multivariate risk analysis revealed Influenza, Peak Insp. Pressure at implantation, pO2\/FiO2 ratio and ECLS Score (SAVE\/RESP) as well as ECLS support time to be independent risk factors for mortality.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Mobile ECLS support is a tremendous challenge. However, it is justified to offer 24\u2009h\/7d ECLS standby for secondary and primary hospitals as a tertiary hospital. Increasing indications and total numbers for ECLS support raise the need for further studies to evaluate outcome in these patients.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-021-01508-9","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T10:08:03Z","timestamp":1622628483000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["ECLS supported transport of ICU patients: does out-of -house implantation impact survival?"],"prefix":"10.1186","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3754-7689","authenticated-orcid":false,"given":"Felix","family":"Fleissner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Mogaldea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Martens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruslan","family":"Natanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"R\u00fcmke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jawad","family":"Salman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Kaufeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Ius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Beckmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Haverich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"K\u00fchn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,2]]},"reference":[{"issue":"1","key":"1508_CR1","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/MAT.0000000000000475","volume":"63","author":"RR Thiagarajan","year":"2017","unstructured":"Thiagarajan RR, Barbaro RP, Rycus PT, Mcmullan DM, Conrad SA, Fortenberry JD, et al. 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