{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T09:51:50Z","timestamp":1770717110443,"version":"3.49.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T00:00:00Z","timestamp":1627689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T00:00:00Z","timestamp":1627689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"chengdu science and technology support program","award":["2019-YFYF-00090-SN"],"award-info":[{"award-number":["2019-YFYF-00090-SN"]}]},{"DOI":"10.13039\/100012542","name":"sichuan province science and technology support program","doi-asserted-by":"publisher","award":["2020JDKP0023"],"award-info":[{"award-number":["2020JDKP0023"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>There were very few reports of Rosai\u2013Dorfman disease in the thymus, which known as sinus histiocytosis with massive lymphadenopathy. It usually accompanied with other systemic symptoms such as fever, malaise, night sweats, or weight loss in the short term.<\/jats:p>\n                <jats:p>Case presentation<\/jats:p>\n                <jats:p>We herein report a rare case of RDD of thymic origin and a review of the literature concerning the clinical and pathological features of this disease, which is often misdiagnosed as thymoma. The patient was underwent thymectomy to extirpate the lesion completely by video-assisted thoracic surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>To the best of our knowledge, this is the fourth thymus occurring RDD case with proof via histology and IHC. Our findings suggest the difficulty of making a diagnosis before surgery and more cases will need to be reported in order to facilitate the preoperative diagnosis of such a rare tumor.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-021-01595-8","type":"journal-article","created":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T21:02:27Z","timestamp":1627765347000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["An extremely rare case of Rosai\u2013Dorfman disease in the thymus"],"prefix":"10.1186","volume":"16","author":[{"given":"Cheng","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,31]]},"reference":[{"issue":"12","key":"1595_CR1","doi-asserted-by":"publisher","first-page":"e25165","DOI":"10.1097\/MD.0000000000025165","volume":"100","author":"M Lee","year":"2021","unstructured":"Lee M, Ryu KH, Baek HJ, et al. Rosai\u2013Dorfman disease with infiltration of IgG4-bearing plasma cells presenting as laryngeal-nasal masses and cervical lymphadenopathy: a case report. Medicine (Baltimore). 2021;100(12):e25165.","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"1595_CR2","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12893-020-01014-0","volume":"21","author":"X Yang","year":"2021","unstructured":"Yang X, Fang C, Sha Y, et al. An extremely rare case of Rosai\u2013Dorfman disease in the spleen. BMC Surg. 2021;21(1):24.","journal-title":"BMC Surg"},{"issue":"12","key":"1595_CR3","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.5858\/arpa.2010-0554-CR","volume":"135","author":"JJ Cangelosi","year":"2011","unstructured":"Cangelosi JJ, Prieto VG, Ivan D. Cutaneous Rosai\u2013Dorfman disease with increased number of eosinophils: coincidence or histologic variant? 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Arch Bronconeumol. 2011;47(3):161\u20132.","journal-title":"Arch Bronconeumol"},{"issue":"2","key":"1595_CR6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1097\/MAJ.0b013e31824e940d","volume":"344","author":"W Wu","year":"2012","unstructured":"Wu W, Cao L, Li Y, Yu X, Huang H, He J. Primary splenic diffuse large B-cell lymphoma in a patient with thymus Rosai\u2013Dorfman disease. Am J Med Sci. 2012;344(2):155\u20139.","journal-title":"Am J Med Sci"},{"issue":"12","key":"1595_CR7","first-page":"3187","volume":"13","author":"L Liu","year":"2020","unstructured":"Liu L, Huang Y, Zeng C. Infantile Rosai\u2013Dorfman disease: an unusual case of neck swelling and a literature review. Int J Clin Exp Pathol. 2020;13(12):3187\u201391.","journal-title":"Int J Clin Exp Pathol"},{"issue":"12","key":"1595_CR8","doi-asserted-by":"publisher","first-page":"2712","DOI":"10.1002\/ccr3.3255","volume":"8","author":"I Amiji","year":"2020","unstructured":"Amiji I, Mohammed U, Salum H, et al. Rosai\u2013Dorfman disease\u2014a rare case of cervical lymphadenopathy. Clin Case Rep. 2020;8(12):2712\u20135.","journal-title":"Clin Case Rep"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-021-01595-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-021-01595-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-021-01595-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T21:05:38Z","timestamp":1627765538000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-021-01595-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,31]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1595"],"URL":"https:\/\/doi.org\/10.1186\/s13019-021-01595-8","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,31]]},"assertion":[{"value":"28 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All the authors consent to publish the paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflicts of interest to declare.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"212"}}