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We aimed to assess the effect of postoperative anticoagulation on false lumen patency and clinical outcomes in relation to false lumen status.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Postoperative computed tomographies of 156 patients undergoing ATAAD DeBakey type I surgery were retrospectively evaluated for false lumen patency. The patients were divided into groups determined by anticoagulation treatment at discharge. Uni- and multivariable logistic regression was used for analysing the effect of anticoagulation on the false lumen, and Kaplan\u2013Meier estimates were used to assess the association of a patent false lumen with the incidence of reoperation and long-term survival.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A patent false lumen was present in 81% of the patients. Postoperative anticoagulants were not associated with a patent false lumen (<jats:italic>p<\/jats:italic>\u2009=\u20090.48) in univariable analysis. In multivariable analysis, both hemiarch replacement (OR 0.15, CI95% 0.05\u20130.49, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and the use of betablockers had a protective effect (OR 0.29, CI95% 0.10\u20130.85, <jats:italic>p<\/jats:italic>\u2009=\u20090.023). The Kaplan\u2013Meier estimates for survival and the composite endpoint of survival and freedom from distal reintervention indicated no difference in outcome between patients in regard to anticoagulation treatment (survival <jats:italic>p<\/jats:italic>\u2009=\u20090.43, composite <jats:italic>p<\/jats:italic>\u2009=\u20090.82<jats:italic>)<\/jats:italic> or false lumen status (survival <jats:italic>p<\/jats:italic>\u2009=\u20090.21, composite <jats:italic>p<\/jats:italic>\u2009=\u20090.09).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study could not show negative effects from the postoperative use of anticoagulants on false lumen status, nor that false lumen patency was associated with poorer prognosis. A hemiarch procedure was shown to be associated with reduced risk of false lumen patency.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-021-01661-1","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T19:06:39Z","timestamp":1632855999000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effect of postoperative anticoagulation on false lumen patency after surgery for acute type A aortic dissection"],"prefix":"10.1186","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2303-2369","authenticated-orcid":false,"given":"M\u00e5rten","family":"Larsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gracijela","family":"Bozovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Sj\u00f6gren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Zindovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigurdur","family":"Ragnarsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahab","family":"Nozohoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"issue":"12","key":"1661_CR1","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1016\/S0002-9149(01)01556-9","volume":"87","author":"Y Bernard","year":"2001","unstructured":"Bernard Y, et al. 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