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We used random- or fixed-effect models to obtain pooled estimates of the success rate and postoperative complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 1650 pediatric patients from 8 publications were included, with a mean age ranging from 3.44 to 8.67\u00a0years old. The pooled estimate of successful implantation was 98.2% (95% CI 97.1\u201399.4%, I<jats:sup>2<\/jats:sup>\u2009=\u200969.4%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), and the incidence of cardiac conduction system complications was 17.4% (95% CI 8.4\u201326.4%, I<jats:sup>2<\/jats:sup>\u2009=\u200996.1%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), among which the incidence of heart block was 14.8% (95% CI 6.4\u201323.3%, I<jats:sup>2<\/jats:sup>\u2009=\u200996.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.001). The incidence of impulse formation disorders was 4.1% (95% CI 0.7\u20137.6%, I<jats:sup>2<\/jats:sup>\u2009=\u200991.7%; <jats:italic>P<\/jats:italic>\u2009=\u20090.019), and the incidence of complete atrioventricular block was 0.8% (95% CI 0.3\u201313%, I<jats:sup>2<\/jats:sup>\u2009=\u20090.0%; <jats:italic>P<\/jats:italic>\u2009=\u20090.001). Risk factors for newly emerging arrhythmias included the VSD size MD\u2009=\u20090.89 (95% CI 0.46\u20131.32, I<jats:sup>2<\/jats:sup>\u2009=\u20090%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and device size MD\u2009=\u20091.26 (95% CI 0.78\u20131.73, I<jats:sup>2<\/jats:sup>\u2009=\u20090%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.00001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Percutaneous catheter intervention is safe and effective in treating pediatric patients with pmVSD, and the risk factors leading to arrhythmias include the sizes of the pmVSD and device.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-022-01751-8","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T23:02:29Z","timestamp":1645052549000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Influence of percutaneous catheter intervention for congenital perimembranous ventricular septal defects in children on the cardiac conduction system and associated risk factors: a meta-analysis"],"prefix":"10.1186","volume":"17","author":[{"given":"Yu-Qing","family":"Lei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Hao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi-Hao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Peng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,16]]},"reference":[{"issue":"3","key":"1751_CR1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1161\/01.CIR.43.3.323","volume":"43","author":"SC Mitchell","year":"1971","unstructured":"Mitchell SC, Korones SB, Berendes HW. 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