{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T00:29:35Z","timestamp":1700267375781},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:00:00Z","timestamp":1696636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:00:00Z","timestamp":1696636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Clinicians continue to expand the availability of transcatheter aortic valve replacement (TAVR) for patients who historically would have been ineligible for surgical aortic valve replacement. Historically, reoperative aortic valve surgery after transplant was immensely complicated and high risk due to the repeat sternotomy approach, and the immunosuppression in transplant patients. As heart transplant patients continue to live longer, patients are beginning to develop novo aortic pathology of the transplanted organ. In these patients, TAVR may be a valuable rescue therapy for those with de-novo aortic valve disease.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>Here, we present a single case of a 70-year-old man with a history of heart transplant 23\u00a0years prior complicated by severe sternal infection and subsequent removal of his sternum. Additionally, this patient had a recent history of kidney transplant due to renal cell carcinoma necessitating nephrectomy. He subsequently developed progressive symptomatic aortic insufficiency and underwent a successful TAVR to treat his new aortic disease.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>To our knowledge, this represents only the second case report of TAVR for severe aortic insufficiency and one of the first reports of TAVR in a multiple organ recipient. TAVR may represent an important rescue therapy for post-transplant valve pathologies instead of high-risk reoperative surgical aortic valve replacement.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-023-02407-x","type":"journal-article","created":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T16:01:52Z","timestamp":1696694512000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcatheter aortic valve replacement 23\u00a0years after heart transplant for aortic insufficiency"],"prefix":"10.1186","volume":"18","author":[{"given":"Andrew","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Amirjamshidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"IV","given":"George","family":"Olverson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick S.","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Hisamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,10,7]]},"reference":[{"issue":"5","key":"2407_CR1","doi-asserted-by":"publisher","first-page":"e66","DOI":"10.1016\/j.athoracsur.2010.08.021","volume":"90","author":"G Bruschi","year":"2010","unstructured":"Bruschi G, De Marco F, Oreglia J, Colombo P, Moreo A, De Chiara B, et al. Transcatheter aortic valve implantation after heart transplantation. Ann Thorac Surg. 2010;90(5):e66\u20138.","journal-title":"Ann Thorac Surg"},{"issue":"10","key":"2407_CR2","doi-asserted-by":"publisher","first-page":"4661","DOI":"10.1016\/j.transproceed.2010.09.148","volume":"42","author":"M Seiffert","year":"2010","unstructured":"Seiffert M, Meyer S, Franzen O, Conradi L, Baldus S, Schirmer J, et al. Transcatheter aortic valve implantation in a heart transplant recipient: a case report. Transplant Proc. 2010;42(10):4661\u20133.","journal-title":"Transplant Proc"},{"issue":"5","key":"2407_CR3","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1016\/j.jaccas.2020.03.028","volume":"2","author":"R Beale","year":"2020","unstructured":"Beale R, Beale C, DeNofrio D, Gordon P, Levine D, Sodha N, et al. Transcatheter aortic valve replacement of a bicuspid aortic valve in a heart transplant recipient. JACC Case Rep. 2020;2(5):716\u201320.","journal-title":"JACC Case Rep"},{"issue":"3","key":"2407_CR4","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1111\/jocs.14438","volume":"35","author":"TJ Wallen","year":"2020","unstructured":"Wallen TJ, Spratt J, Kates MM, Wayangankar S, Vilaro J, Aranda J, et al. Transcatheter aortic valve replacement 24 years after cardiac transplantation. J Card Surg. 2020;35(3):710\u20132.","journal-title":"J Card Surg"},{"issue":"4","key":"2407_CR5","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1111\/jocs.16237","volume":"37","author":"J Forcillo","year":"2022","unstructured":"Forcillo J. Less invasive treatments for pure aortic insufficiency: Are we there yet? J Card Surg. 2022;37(4):893\u20134.","journal-title":"J Card Surg"},{"key":"2407_CR6","doi-asserted-by":"publisher","unstructured":"Rawasia WF, Khan MS, Usman MS, Siddiqi TJ, Mujeeb FA, Chundrigar M, Kalra A, Alkhouli M, Kavinsky CJ, Bhatt DL. Safety and efficacy of transcatheter aortic valve replacement for native aortic valve regurgitation: A systematic review and meta-analysis. Catheter Cardiovasc Interv. 2019;93(2):345\u201353. https:\/\/doi.org\/10.1002\/ccd.27840.","DOI":"10.1002\/ccd.27840"},{"key":"2407_CR7","doi-asserted-by":"crossref","unstructured":"Markham R, Ghodsian M, Sharma R (2020) TAVR in patients with pure aortic regurgitation: ready to use? Curr Cardiol Rep 22(9):98.","DOI":"10.1007\/s11886-020-01338-6"},{"issue":"3","key":"2407_CR8","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1053\/j.jvca.2016.07.026","volume":"31","author":"S Margale","year":"2017","unstructured":"Margale S, Natani S. Anesthetic management of transfemoral transcatheter aortic valve replacement (TAVR) in a heart transplant recipient with severely depressed left ventricular function and renal failure. J Cardiothorac Vasc Anesth. 2017;31(3):1032\u20136.","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2407_CR9","doi-asserted-by":"publisher","unstructured":"Campany ME, Bhandarkar AR, Bydon M, Donato BB, Sell-Dottin KA. Transcatheter aortic valve replacement outcomes in solid organ transplant recipients. J Card Surg. 2022;37(3):602\u20137. https:\/\/doi.org\/10.1111\/jocs.16202","DOI":"10.1111\/jocs.16202"},{"key":"2407_CR10","doi-asserted-by":"crossref","unstructured":"B\u00fcttner S, Z\u00f6ller C, Patyna S, Gradascevic A, Weiler H, Rosenberg M, Walther, T, Zeiher AM, Geiger H, Vasa-Nicotera M, Hauser I, Fichtlscherer S. Risk of graft loss in kidney transplant recipients after aortic valve replacement. Bosn J Basic Med Sci. 2022;23:145.","DOI":"10.17305\/bjbms.2022.7720"},{"key":"2407_CR11","doi-asserted-by":"crossref","unstructured":"Zaid S, Sengupta A, Okoli K, Tsoi M, Khan A, Ahmad H, Goldberg JB, Undemir C, Rozenshtein A, Patel N, Khan M, Gupta E, Kovacic J, Lansman SL, Dangas GD, Sharma SK, Kini A, Tang GHL. Novel anatomic predictors of new persistent left bundle branch block after evolut transcatheter aortic valve implantation. Am J Cardiol. 2020;125(8):1222\u20139.","DOI":"10.1016\/j.amjcard.2020.01.008"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-023-02407-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-023-02407-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-023-02407-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T21:49:30Z","timestamp":1700257770000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-023-02407-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,7]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["2407"],"URL":"https:\/\/doi.org\/10.1186\/s13019-023-02407-x","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,7]]},"assertion":[{"value":"13 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This was submitted to the University of Rochester RSRB (ID#7596). RSRB approval was waived on October 27, 2022. Informed consent for participation and publication has been obtained as of October 21, 2022.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"274"}}