{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:15:32Z","timestamp":1787242532368,"version":"build-2736575974"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T00:00:00Z","timestamp":1700092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T00:00:00Z","timestamp":1700092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary cardiac myxofibrosarcoma is rare and commonly occurs in the left atrium. Myxofibrosarcoma is aggressive and has a high mortality rate due to its high rate of recurrence. Complete surgical resection is considered important; however, effective treatment options have not been established.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report the case of a 75-year-old woman who developed a myxofibrosarcoma spreading to the left atrium and pericardium. We performed surgical resection of the tumor to prevent sudden death due to mitral valve obstruction or cerebral infarction due to embolism of the scattered mass. However, we were unable to complete the resection of the tumors. The patient developed brain metastasis 2 months after surgery and eventually died due to brain hemorrhage 3 months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this report, we described a rare case of primary cardiac myxofibrosarcoma located not only in the left atrium but also in the pericardium. Considering preoperative laboratory findings, surgical and adjuvant therapy, and the patient\u2019s wishes are important for the best therapeutic course for an individual.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-023-02441-9","type":"journal-article","created":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T14:03:31Z","timestamp":1700143411000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Primary cardiac myxofibrosarcoma of the left atrium and pericardium: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Ryota","family":"Azuma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Sunadoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utano","family":"Tomaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Motohashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,16]]},"reference":[{"issue":"4","key":"2441_CR1","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1097\/00000478-199604000-00001","volume":"20","author":"T Mentzel","year":"1996","unstructured":"Mentzel T, Calonge E, Wadden C, Camplejohn RS, Beham A, Smith MA, et al. Myxofibrosarcoma - clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol. 1996;20(4):391\u2013405.","journal-title":"Am J Surg Pathol"},{"key":"2441_CR2","doi-asserted-by":"crossref","unstructured":"Sun DD, Wu YP, Liu Y, Yang J. Primary cardiac myxofibrosarcoma: case report, literature review and pooled analysis. BMC Cancer. 2018;18.","DOI":"10.1186\/s12885-018-4434-2"},{"issue":"5","key":"2441_CR3","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1177\/0003319707306079","volume":"59","author":"GA Lazaros","year":"2008","unstructured":"Lazaros GA, Matsakas EP, Madas JS, Toli DI, Nikas DJ, Kershaw MA, et al. Primary myxofibrosarcoma of the Left Atrium: Case Report and Review of the literature. Angiology. 2008;59(5):632\u20135.","journal-title":"Angiology"},{"key":"2441_CR4","doi-asserted-by":"crossref","unstructured":"Ujihira K, Yamada A, Nishioka N, Iba Y, Maruyama R, Nakanishi K et al. 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