{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T20:06:07Z","timestamp":1794081967523,"version":"4.8.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T00:00:00Z","timestamp":1706400000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T00:00:00Z","timestamp":1706400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mediastinal teratoma is an uncommon disease, nevertheless they represent the most common mediastinal germ cell tumors. It may grow silently for several years and remain undiagnosed until the occurrence of a complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The main aim of this article is to illustrate the silent evolution of an anterior mediastinal teratoma for over 70 years without presenting any notable complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We present the case of a 70-year-old female, treated for hypertension referred to our department for managing a voluminous mediastinal mass, discovered fortuitously by a general practitioner in a chest X-ray. The anamnesis didn\u2019t relate any chest pain, cough, dyspnea nor hemoptysis. The clinical examination, in particular pleuropulmonary, was unremarkable. The workup (Chest X-Ray and CT scan) demonstrated a voluminous pleural mass at the expense of the right mediastinal pleura, rounded in shape, with calcified wall and fluid content. Blood tests did not demonstrate eosinophilia, and hydatid IgG serology was negative. serum human chorionic gonadotropin (hCG) and alpha fetoprotein (AFP) levels were found to be normal. The patient subsequently underwent a right posterolateral thoracotomy with resection of the lesion. The mass was dissected very carefully and then resected in toto. The macroscopic and microscopic histological examination demonstrated a mature cystic teratoma. Surgical resection was an adequate treatment and the prognosis was excellent for the patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cystic mature teratomas are rare thoracic tumors, often recognized by radiological examination. This article relates the silent evolution that a teratoma could have, and the late appearance of symptoms that it could have.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-024-02503-6","type":"journal-article","created":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T05:02:07Z","timestamp":1706418127000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Surgical management of mediastinal mature cystic teratoma of the elderly remaining asymptomatic"],"prefix":"10.1186","volume":"19","author":[{"given":"Badreddine","family":"Belayachi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hicham","family":"Fenane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassine","family":"Msougar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,28]]},"reference":[{"issue":"5","key":"2503_CR1","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s00428-015-1830-8","volume":"467","author":"MA Den Bakker","year":"2015","unstructured":"Den Bakker MA, Marx A, Mukai K, Str\u00f6bel P. Mesenchymal tumours of the mediastinum\u2014part I. Virchows Arch. 2015;467(5):487\u2013500.","journal-title":"Virchows Arch"},{"issue":"9","key":"2503_CR2","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1097\/JTO.0000000000000630","volume":"10","author":"WD Travis","year":"2015","unstructured":"Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, et al. The 2015 World Health Organization Classification of Lung Tumors. J Thorac Oncol. 2015;10(9):1243\u201360.","journal-title":"J Thorac Oncol"},{"issue":"4","key":"2503_CR3","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1378\/chest.128.4.2893","volume":"128","author":"BV Duwe","year":"2005","unstructured":"Duwe BV, Sterman DH, Musani AI. Tumors of the Mediastinum. Chest. 2005;128(4):2893\u2013909.","journal-title":"Chest"},{"issue":"6","key":"2503_CR4","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1002\/jmri.22377","volume":"32","author":"K Takahashi","year":"2010","unstructured":"Takahashi K, Al-Janabi NJ. Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging. 2010;32(6):1325\u201339.","journal-title":"J Magn Reson Imaging"},{"issue":"7","key":"2503_CR5","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1016\/j.jpedsurg.2004.03.045","volume":"39","author":"H Isaacs","year":"2004","unstructured":"Isaacs H. Perinatal (fetal and neonatal) germ cell tumors. J Pediatr Surg. 2004;39(7):1003\u201313.","journal-title":"J Pediatr Surg"},{"key":"2503_CR6","doi-asserted-by":"publisher","first-page":"18","DOI":"10.21037\/med.2018.12.03","volume":"3","author":"BW Carter","year":"2019","unstructured":"Carter BW, Benveniste MF, Marom EM. Diagnostic approach to the anterior\/prevascular mediastinum for radiologists. Mediastinum. 2019;3:18\u20138.","journal-title":"Mediastinum"},{"key":"2503_CR7","unstructured":"Kang J, Mashaal H, Anjum F. Mediastinal Germ Cell Tumors. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Oct 7]. Available from: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563232\/."},{"key":"2503_CR8","unstructured":"Almeida PT, Heller D. Anterior Mediastinal Mass. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [cited 2023 Oct 8]. Available from: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK546608\/."},{"issue":"1","key":"2503_CR9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/s13019-020-1076-7","volume":"15","author":"LH Pham","year":"2020","unstructured":"Pham LH, Trinh DK, Nguyen AV, Nguyen LS, Le DT, Nguyen DH, et al. Thoracoscopic surgery approach to mediastinal mature teratomas: a single-center experience. J Cardiothorac Surg. 2020;15(1):35.","journal-title":"J Cardiothorac Surg"},{"issue":"4","key":"2503_CR10","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1080\/00015458.2020.1722932","volume":"120","author":"EH Kabiri","year":"2020","unstructured":"Kabiri EH, Hammoumi ME, Bhairis M, Oukabli M. Mediastinal calcified hydatid cyst. Acta Chir Belg. 2020;120(4):297\u20138.","journal-title":"Acta Chir Belg"},{"key":"2503_CR11","doi-asserted-by":"crossref","unstructured":"Rathore R. Clinicopathological evaluation of 223 cases of mature cystic Teratoma, Ovary: 25-Year experience in a single Tertiary Care Centre in India. JCDR [Internet]. 2017 [cited 2023 Oct 8].","DOI":"10.7860\/JCDR\/2017\/23909.9612"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02503-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02503-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02503-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T05:06:04Z","timestamp":1706418364000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02503-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,28]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2503"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02503-6","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-2053576\/v1","asserted-by":"object"}]},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,28]]},"assertion":[{"value":"11 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the patient for the publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}