{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T11:50:49Z","timestamp":1707652249489},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cardiac papillary fibroelastoma is a rare benign tumor, which is often mistaken for a vegetation. Predominantly asymptomatic, it can cause life-threatening complications. Although rare, mobile papillary fibroelastoma movement between affected valves may hamper valve closure and damage the valve, leading to valvular regurgitation. Endothelial damage increases the risk of developing infective endocarditis. We report a rare case of a highly mobile papillary fibroelastoma originating from the atrial septum touching the mitral valve, leading to mitral regurgitation and, eventually, infective endocarditis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 26-year-old woman with suspected infective endocarditis was referred to us from a previous hospital after having experienced intermittent fever for a month. Before the fever, she had been experiencing exertional dyspnea. In addition, she had undergone a cesarean section two weeks before this admission. A transthoracic echocardiogram showed a mobile mass originating from the atrial septum touching the mitral valve with severe mitral regurgitation. Computed tomography revealed an occluded right profunda femoris artery with an embolus. Infective endocarditis associated with a mobile vegetation with high embolic risk was diagnosed, and urgent surgery was performed. Following the surgery, examinations revealed papillary fibroelastoma originating from the atrial septum and infective endocarditis of the mitral valve. The histopathological examination confirmed that a mass initially thought to be a mobile vegetation was a papillary fibroelastoma. The postoperative course was uneventful except for pericarditis. There has been no recurrence of infective endocarditis or papillary fibroelastoma.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The highly mobile papillary fibroelastoma was thought to have caused both chronic mitral regurgitation and infective endocarditis. Mobile papillary fibroelastomas can cause endothelial damage to nearby valves and predispose patients to infective endocarditis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-024-02584-3","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T16:02:13Z","timestamp":1707494533000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Papillary fibroelastoma originating from the atrial septum touching the mitral valve leading to infective endocarditis: a case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Koji","family":"Funaishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiko","family":"Oki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyori","family":"Nakatogawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Yamanoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,9]]},"reference":[{"key":"2584_CR1","doi-asserted-by":"publisher","first-page":"2687","DOI":"10.1161\/01.CIR.103.22.2687","volume":"103","author":"JP Sun","year":"2001","unstructured":"Sun JP, Asher CR, Yang XS, Cheng GG, Scalia GM, Massed AG, et al. Clinical and echocardiographic characteristics of papillary fibroelastomas: a retrospective and prospective study in 162 patients. Circulation. 2001;103:2687\u201393.","journal-title":"Circulation"},{"key":"2584_CR2","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/S0002-8703(03)00249-7","volume":"146","author":"RM Gowda","year":"2003","unstructured":"Gowda RM, Khan IA, Nair CK, Mehta NJ, Vasavada BC, Sacchi TJ. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003;146:404\u201310.","journal-title":"Am Heart J"},{"key":"2584_CR3","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.athoracsur.2012.04.006","volume":"94","author":"MM Anastacio","year":"2012","unstructured":"Anastacio MM, Moon MR, Damiano RJ Jr, Pasque MK, Maniar HS, Lawton JS. Surgical experience with cardiac papillary fibroelastoma over a 15-year period. 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BMJ Case Rep. 2020;13:e234828.","journal-title":"BMJ Case Rep"},{"key":"2584_CR6","doi-asserted-by":"publisher","first-page":"e269","DOI":"10.1016\/j.athoracsur.2021.12.047","volume":"114","author":"AG Iosifescu","year":"2022","unstructured":"Iosifescu AG, Enache R, V\u0103leanu L, Timisescu AT, Iliescu VA. Ten tumors in the heart: papillary fibroelastoma with triple valve involvement. Ann Thorac Surg. 2022;114:e269\u201372.","journal-title":"Ann Thorac Surg"},{"key":"2584_CR7","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1253\/circj.66.305","volume":"66","author":"T Koji","year":"2002","unstructured":"Koji T, Fujioka M, Imai H, Komada T, Takeuchi M, Ichikawa T, et al. Infected papillary fibroelastoma attached to the atrial septum. Circ J. 2002;66:305\u20137.","journal-title":"Circ J"},{"key":"2584_CR8","doi-asserted-by":"publisher","first-page":"3232","DOI":"10.1161\/CIRCULATIONAHA.108.782292","volume":"119","author":"KK Stout","year":"2009","unstructured":"Stout KK, Verrier ED. Acute valvular regurgitation. Circulation. 2009;119:3232\u201341.","journal-title":"Circulation"},{"key":"2584_CR9","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/S1684-1182(10)60074-6","volume":"43","author":"PY Liu","year":"2010","unstructured":"Liu PY, Huang YF, Tang CW, Chen YY, Hsieh KS, Ger LP, et al. Staphylococcus lugdunensis infective endocarditis: a literature review and analysis of risk factors. J Microbiol Immunol Infect. 2010;43:478\u201384.","journal-title":"J Microbiol Immunol Infect"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02584-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02584-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02584-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T16:05:56Z","timestamp":1707494756000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02584-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,9]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2584"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02584-3","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,9]]},"assertion":[{"value":"26 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for this report was obtained from the ethics committee of our hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for the publication of this case report and accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"79"}}