{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:47:40Z","timestamp":1785419260367,"version":"3.56.0"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Zhejiang Educational Committee","award":["Y201839456"],"award-info":[{"award-number":["Y201839456"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Right-side heart mass can be found incidentally on routine transthoracic echocardiography (TTE). Accurate diagnosis of cardiac mass often requires more than one imaging method. We present a mid-age woman with non-Hodgkin lymphoma who was found to have multiple right atrial masses mimicking metastases on routine TTE, which were finally diagnosed as thrombi by multimodal cardiac imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 52-year-old woman was diagnosed with primary mediastinal diffuse large B cell lymphoma (DLBCL) almost six months prior. The TTE revealed multiple masses in the right atrium with normal cardiac function when she was being evaluated for the next chemotherapy. On arrival, she was hemodynamically stable and asymptomatic. Physical examination was no remarkable. Laboratory findings showed leukocytosis of 17,900 cells\/mm3, hemoglobin of 7.5\u00a0mg\/dL, and a normal D-dimer level. The suspicious diagnosis of right atrial metastasis was made by TEE. However, the diagnosis of right atrial thrombi was made by contrast CMR. Finally, the 18\u00a0F-FDG PET-CT demonstrated no metabolic activity in the right atrium, which further supported the diagnosis of thrombi. Eventually, the masses were removed by cardiopulmonary bypass thoracotomy because of a high risk of pulmonary embolism. Histopathology confirmed the diagnosis of thrombi.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case highlights the importance of multimodality cardiac imaging in the appropriate diagnosis of a RA masses in patient of lymphoma. Diagnosis of RA masses can be made using multimodal cardiac imaging like TTE, TEE and CMR, even PET. Echocardiography is the most commonly used on multimodal imaging in cardiac thrombus. CMR has high specificity in differentiating a tumor from thrombus, while 18\u00a0F-FDG PET has good sensitivity to determine the nature of the masses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-024-02650-w","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T08:02:16Z","timestamp":1711958536000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Multiple thrombi mimicking metastases in the right atrium of patients with non-Hodgkin\u2019s lymphoma diagnosed by multimodal cardiac imaging: one case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Zhiqiang","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Mou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,1]]},"reference":[{"issue":"6","key":"2650_CR1","doi-asserted-by":"publisher","first-page":"856","DOI":"10.2967\/jnumed.111.095364","volume":"53","author":"K Rahbar","year":"2012","unstructured":"Rahbar K, et al. Differentiation of malignant and benign cardiac tumors using 18F-FDG PET\/CT. J Nucl Med. 2012;53(6):856\u201363.","journal-title":"J Nucl Med"},{"key":"2650_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.hjc.2022.07.008","volume":"68","author":"FQ Goh","year":"2022","unstructured":"Goh FQ, et al. Clinical characteristics, treatment and long-term outcomes of patients with right-sided cardiac thrombus. Hellenic J Cardiol. 2022;68:1\u20138.","journal-title":"Hellenic J Cardiol"},{"issue":"9","key":"2650_CR3","first-page":"896","volume":"7","author":"P Pazos-L\u00f3pez","year":"2014","unstructured":"Pazos-L\u00f3pez P, et al. Value of CMR for the Differential diagnosis of Cardiac masses. JACC: Cardiovasc Imaging. 2014;7(9):896\u2013905.","journal-title":"JACC: Cardiovasc Imaging"},{"key":"2650_CR4","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.ijcard.2016.03.059","volume":"212","author":"M Rinuncini","year":"2016","unstructured":"Rinuncini M, et al. Differentiation of cardiac thrombus from cardiac tumor combining cardiac MRI and 18F-FDG-PET\/CT imaging. Int J Cardiol. 2016;212:94\u20136.","journal-title":"Int J Cardiol"},{"issue":"1","key":"2650_CR5","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1148\/radiol.13121239","volume":"268","author":"M Motwani","year":"2013","unstructured":"Motwani M, et al. MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 2013;268(1):26\u201343.","journal-title":"Radiology"},{"issue":"7","key":"2650_CR6","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/S0002-9149(03)00911-1","volume":"92","author":"U Hoffmann","year":"2003","unstructured":"Hoffmann U, et al. Usefulness of magnetic resonance imaging of cardiac and paracardiac masses. Am J Cardiol. 2003;92(7):890\u20135.","journal-title":"Am J Cardiol"},{"issue":"7","key":"2650_CR7","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1007\/s00259-022-05709-9","volume":"49","author":"N Mikail","year":"2022","unstructured":"Mikail N, et al. Diagnosis and staging of cardiac masses: additional value of CMR with (18)F-FDG-PET compared to CMR with CECT. Eur J Nucl Med Mol Imaging. 2022;49(7):2232\u201341.","journal-title":"Eur J Nucl Med Mol Imaging"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02650-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02650-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02650-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T08:07:27Z","timestamp":1711958847000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02650-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,1]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2650"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02650-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3376395\/v1","asserted-by":"object"}]},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,1]]},"assertion":[{"value":"21 September 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from patient included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Written informed consent of clinical detail and image publication was obtained from the patient.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"165"}}