{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:38:35Z","timestamp":1787020715622,"version":"build-2736575974"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Immunoglobulin (Ig)G4-related disease affects nearly every organ, and its clinical course varies depending on the involved organ; however, its occurrence in the mediastinum is rarely reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 58-year-old woman presented with a posterior mediastinal tumor along the thoracic spine on imaging. Based on her elevated serum IgG4 level of 349.7\u00a0mg\/dL, IgG4-related disease was suspected. Since the tumor was growing and malignancy could not be excluded, surgical resection was performed for definitive diagnosis. Robot-assisted thoracoscopic surgery was performed via the left semipronation and right thoracic approaches. The irregularly-shaped tumor was located on the level of the seventh to ninth thoracic vertebra, along the sympathetic nerve. A malignancy was not excluded based on the appearance of the tumor. The tumor had poor mobility. The sympathetic nerves, intercostal arteries, and veins were also excised. In this case, the articulated forceps, used during the robotic surgery, were useful in achieving complete tumor resection along the vertebral body. The pathological examination revealed IgG4-positive plasma infiltration, which fulfilled the criteria for IgG4-related diseases. The postoperative course was uneventful, and the patient underwent follow-up on an outpatient basis without additional medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical presentation of IgG4-related disease varies, based on the involved organs. This case was rare because the mediastinum was involved, and it emphasized the effectiveness of surgical resection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-024-02655-5","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T03:02:09Z","timestamp":1715828529000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Robot-assisted thoracoscopic resection of a posterior mediastinal tumor with immunoglobulin G4-related disease: a case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Taihei","family":"Takeuchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromitsu","family":"Takizawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimi","family":"Bando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Hosokawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Sumitomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Morishita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Kawakita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Toba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,16]]},"reference":[{"key":"2655_CR1","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1146\/annurev-med-050219-034449","volume":"73","author":"G Katz","year":"2022","unstructured":"Katz G, Stone JH. Clinical perspectives on IgG4-related disease and its classification. Annu Rev Med. 2022;73:545\u20132.","journal-title":"Annu Rev Med"},{"key":"2655_CR2","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/joim.13477","volume":"292","author":"Z Liu","year":"2022","unstructured":"Liu Z, Peng Y, Li J, Lu H, Peng L, Zhou J, et al. Prediction of new organ onset in recurrent immunoglobulin G4\u2013related disease during 10 years of follow-up. J Int Med. 2022;292:91\u2013102.","journal-title":"J Int Med"},{"key":"2655_CR3","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1111\/ases.12450","volume":"11","author":"T Uchida","year":"2018","unstructured":"Uchida T, Matsubara H, Nagasaka S, Kina S, Ichihara T, Matsuoka H, et al. Video-assisted thoracoscopic surgery can help enable the complete resection of a mediastinal tumor caused by immunoglobulin G4-related disease and avoid the need for postoperative medication: a case report. Asian J Endosc Surg. 2018;11:248\u201351.","journal-title":"Asian J Endosc Surg"},{"key":"2655_CR4","first-page":"332","volume":"8","author":"A Itaru Hosaka","year":"2019","unstructured":"Itaru Hosaka A, Tanaka M, Sakuraba H, Yamasaki K, Makita Y, Fukasawa. A case report of dumbbell-shaped IgG4-related disease located in the posterior mediastinum. Annals Japanese Respiratory Soc. 2019;8:332\u20135.","journal-title":"Annals Japanese Respiratory Soc"},{"key":"2655_CR5","doi-asserted-by":"publisher","first-page":"e0958","DOI":"10.1002\/rcr2.958","volume":"10","author":"Y Hirai","year":"2022","unstructured":"Hirai Y, Iwamoto R, Iguchi H, Fusamoto A, Yata Y, Ohashi T, et al. IgG4-associated fibrosing mediastinitis requiring differentiation from posterior mediastinal tumour: a case report. Respirol Case Rep. 2022;10:e0958.","journal-title":"Respirol Case Rep"},{"key":"2655_CR6","doi-asserted-by":"publisher","first-page":"213","DOI":"10.2482\/haigan.61.213","volume":"61","author":"M Ozasa","year":"2021","unstructured":"Ozasa M, Sawai T, Harada Y, Yoshioka S, Matsuo N, Mukae H. A case of IgG4-related Disease composed of a paravertebral tumor alone with multiple lung cancers. Japan Lung Cancer Soc. 2021;61:213\u20137.","journal-title":"Japan Lung Cancer Soc"},{"key":"2655_CR7","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.21037\/jtd-20-286","volume":"12","author":"XK Li","year":"2020","unstructured":"Li XK, Cong ZZ, Xu Y, Zhou H, Wu WJ, Wang GM, et al. Clinical efficacy of robot-assisted thoracoscopic surgery for posterior mediastinal neurogenic tumors. J Thorac Dis. 2020;12:3065\u201372.","journal-title":"J Thorac Dis"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02655-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02655-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02655-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T03:04:10Z","timestamp":1715828650000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02655-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,16]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2655"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02655-5","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,16]]},"assertion":[{"value":"22 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 May 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"291"}}