{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:20:45Z","timestamp":1790266845317,"version":"4.1.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Hyperparathyroidism (HPT) is a disease caused by hypersecretion of one or more parathyroid glands, it can be associated with ectopic mediastinal parathyroid glands (MEPA) in 2% of cases. The use of video-assisted thoracoscopic surgery (VATS) for the surgical resection of these glands is a safe, cost-effective, and low morbidity option for patients with MEPA. We report a case series of patients with this disease managed with VATS, the first in Mexico and Latinamerica.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>From 2008 to 2022, a retrospective study involving patients with MEPA and treated by VATS approach was performed in a tertiary hospital in Mexico city. Relevant biochemical and clinical variables such as imaging studies, pre and postoperative laboratory results, surgical strategy, outcomes and pathological analysis were analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Four cases of mediastinal parathyroid adenomas causing HPT were included. All patients were female with a median age of 52.5 years-old (range 46\u201359 years), half of the patients had primary HPT and the others tertiary HPT after kidney transplant. 75% of cases had a MEPA in the medium mediastinum, all had a preoperative positive SPECT-CT 99mTc Sestamibi scan. Mean preoperative PTH was 621.3pg\/mL (182-1382pg\/mL). All patients successfully underwent parathyroidectomy with a VATS approach, no deaths were reported.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>VATS is a minimally invasive surgery that provides adequate access to mediastinal located glands, optimal visualization of mediastinal structures and has a high resection success rate with less complications and morbidity than open approaches.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-024-02694-y","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T14:02:13Z","timestamp":1712239333000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Thoracoscopic treatment of mediastinal ectopic parathyroid adenomas: a Latinamerica experience case series and literature review"],"prefix":"10.1186","volume":"19","author":[{"given":"Chavez","family":"Karla Veronica","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chavez-Tostado","family":"Mariana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pe\u00f1a-Rivera","family":"Adriana Graciela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cervantes-Perez","family":"Gabino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bola\u00f1os-Morales","family":"Francina Valezka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"key":"2694_CR1","doi-asserted-by":"publisher","unstructured":"Kitada M, Yasuda S, Nana T, Ishibashi K, Hayashi S, Okazaki S. Surgical treatment for mediastinal parathyroid adenoma causing primary hyperparathyroidism. J Cardiothorac Surg [Internet]. 2016;11(1):11\u20134. https:\/\/doi.org\/10.1186\/s13019-016-0461-8.","DOI":"10.1186\/s13019-016-0461-8"},{"key":"2694_CR2","doi-asserted-by":"crossref","unstructured":"Long KL, Lee CY, Ramaiah C, Sloan DA. Intrapericardial parathyroid adenoma\u2020. J Surg case reports [Internet]. 2013 Aug 29 [cited 2022 Oct 28];2013(8):rjt064\u2013rjt064. https:\/\/pubmed.ncbi.nlm.nih.gov\/24964470\/.","DOI":"10.1093\/jscr\/rjt064"},{"key":"2694_CR3","unstructured":"Fischer JE, Jones DB, Pomposelli FBUJG. Mastery of surgery. 6th ed. Lippincott Williams & Wilkins; 2012."},{"issue":"4","key":"2694_CR4","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1308\/003588415X14181254789088","volume":"97","author":"J Hu","year":"2015","unstructured":"Hu J, Ngiam KY, Parameswaran R. Mediastinal parathyroid adenomas and their surgical implications. Ann R Coll Surg Engl. 2015;97(4):259\u201361.","journal-title":"Ann R Coll Surg Engl"},{"issue":"6","key":"2694_CR5","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1016\/S0022-5347(17)50098-1","volume":"132","author":"HM Spence","year":"1984","unstructured":"Spence HM. The life and death of Captain Charles Martell and kidney stone disease. J Urol. 1984;132(6):1204\u20137.","journal-title":"J Urol"},{"key":"2694_CR6","doi-asserted-by":"crossref","unstructured":"Carneiro DM, Solorzano CC, Nader MC, Ramirez M, Irvin GL. Comparison of intraoperative iPTH assay (QPTH) criteria in guiding parathyroidectomy: which criterion is the most accurate? Surgery [Internet]. 2003 Dec [cited 2019 Oct 28];134(6):973\u20139; discussion 979\u2009\u2013\u200981. https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003960600300480X.","DOI":"10.1016\/j.surg.2003.06.001"},{"key":"2694_CR7","doi-asserted-by":"crossref","unstructured":"Sreevathsa MR, Melanta K. Unilateral Exploration for Parathyroid Adenoma. Indian J Surg Oncol [Internet]. 2017 Jun 1 [cited 2022 Oct 28];8(2):142\u20135. https:\/\/pubmed.ncbi.nlm.nih.gov\/28546708\/.","DOI":"10.1007\/s13193-016-0605-2"},{"issue":"10","key":"2694_CR8","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1001\/jamasurg.2016.2310","volume":"151","author":"SM Wilhelm","year":"2016","unstructured":"Wilhelm SM, Wang TS, Ruan DT, Lee JA, Asa SL, Duh QY, et al. The American association of endocrine surgeons guidelines for definitive management of primary hyperparathyroidism. JAMA Surg. 2016;151(10):959\u201368.","journal-title":"JAMA Surg"},{"key":"2694_CR9","doi-asserted-by":"crossref","unstructured":"Medrano C, Hazelrigg SR, Landreneau RJ, Boley TM, Shawgo T, Grasch A. Thoracoscopic resection of ectopic parathyroid glands. 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