{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T13:02:26Z","timestamp":1784293346371,"version":"3.55.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T00:00:00Z","timestamp":1712361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T00:00:00Z","timestamp":1712361600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Freiburg"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The occurrence of ectopic pancreas in the mediastinum is rare. Herein, we report a 22-year-old female who presented with right shoulder pain, dysphagia, fever and headaches. Chest computer tomography revealed a mass in the posterior mediastinum with accompanying signs of acute mediastinitis. Needle biopsy and fine-needle aspiration revealed ectopic gastral tissue and ectopic pancreas tissue, respectively. Surgical resection was attempted due to recurring acute pancreatitis episodes. However, due to chronic-inflammatory adhesions of the mass to the tracheal wall, en-bloc resection was not possible without major tracheal resection. Since then, recurring pancreatitis episodes have been treated conservatively with antibiotics. We report this case due to its differing clinical and radiological findings in comparison to previous case reports, none of which pertained a case of ectopic pancreas tissue in the posterior mediastinum with recurring acute pancreatitis and mediastinitis.<\/jats:p>","DOI":"10.1186\/s13019-024-02698-8","type":"journal-article","created":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T06:01:48Z","timestamp":1712383308000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ectopic pancreas tissue in the posterior mediastinum"],"prefix":"10.1186","volume":"19","author":[{"given":"Zeynep","family":"Berkarda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmina","family":"Kuvendjiska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Bamberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Kotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,6]]},"reference":[{"issue":"4","key":"2698_CR1","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1136\/thx.32.4.512","volume":"32","author":"MJ Carr","year":"1977","unstructured":"Carr MJ, Deiraniya AK, Judd PA. Mediastinal cyst containing mural pancreatic tissue. Thorax. 1977;32(4):512\u20136. https:\/\/doi.org\/10.1136\/thx.32.4.512. PMID: 337563; PMCID: PMC470664.","journal-title":"Thorax"},{"issue":"6","key":"2698_CR2","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1016\/S0096-5588(20)30300-7","volume":"34","author":"AJ Shillitoe","year":"1957","unstructured":"Shillitoe AJ, Wilson JE. Enterogenous cyst of thorax with pancreatic tissue as a constituent. J Thorac Surg. 1957;34(6):810\u20134. PMID: 13482025.","journal-title":"J Thorac Surg"},{"key":"2698_CR3","unstructured":"Perez-Ordonez B, Wesson DE, Smith CR, Asa SL. A pancreatic cyst of the anterior mediastinum. Mod Pathol. 1996;9(3):210-4. PMID: 8685216."},{"key":"2698_CR4","doi-asserted-by":"publisher","unstructured":"Cagirici U, Ozbaran M, Veral A, Posacioglu H. Ectopic mediastinal pancreas. Eur J Cardiothorac Surg. 2001;19(4):514-5. https:\/\/doi.org\/10.1016\/s1010-7940(01)00606-6. PMID: 11306324.","DOI":"10.1016\/s1010-7940(01)00606-6"},{"issue":"4","key":"2698_CR5","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0300-2896(04)75500-3","volume":"40","author":"M Iglesias Sent\u00eds","year":"2004","unstructured":"Iglesias Sent\u00eds M, Belda Sanch\u00eds J, Gimferrer Garolera JM, Catal\u00e1n Biela M, Rubio Garay M, Ram\u00edrez Ruz J. Quiste ent\u00e9rico mediast\u00ednico: presentaci\u00f3n cl\u00ednica e histopatolog\u00eda inusuales [Mediastinal enteric cyst: unusual clinical presentation and histopathology]. Arch Bronconeumol. 2004;40(4):185\u20137. Spanish. PMID: 15030734.","journal-title":"Arch Bronconeumol"},{"key":"2698_CR6","doi-asserted-by":"publisher","unstructured":"Tamura Y, Takahama M, Kushibe K, Taniguchi S. Ectopic pancreas in the anterior mediastinum. Jpn J Thorac Cardiovasc Surg. 2005;53(9):498\u2013501. https:\/\/doi.org\/10.1007\/s11748-005-0095-6. PMID: 16200892.","DOI":"10.1007\/s11748-005-0095-6"},{"key":"2698_CR7","doi-asserted-by":"publisher","unstructured":"Al-Salam S, Al Ashari M. Ectopic pancreatic tissue in the anterior mediastinum. Virchows Arch. 2006;448(5):661-3. https:\/\/doi.org\/10.1007\/s00428-006-0159-8. Epub 2006 Mar 1. PMID: 16508781.","DOI":"10.1007\/s00428-006-0159-8"},{"key":"2698_CR8","doi-asserted-by":"publisher","unstructured":"Wang W, Li K, Qin W, Sun H, Zhao C. Ectopic pancreas in mediastinum: report of 2 cases and review of the literature. J Thorac Imaging. 2007;22(3):256-8. https:\/\/doi.org\/10.1097\/01.rti.0000213587.44719.a7. PMID: 17721336.","DOI":"10.1097\/01.rti.0000213587.44719.a7"},{"key":"2698_CR9","doi-asserted-by":"publisher","unstructured":"Chen ZH, Yu RS, Dong F, Wang XJ. CT findings of an ectopic pancreas in the anterior mediastinum. Korean J Radiol. 2009;10(5):527\u201330. https:\/\/doi.org\/10.3348\/kjr.2009.10.5.527. Epub 2009 Aug 25. PMID: 19721841; PMCID: PMC2731874.","DOI":"10.3348\/kjr.2009.10.5.527"},{"key":"2698_CR10","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1016\/j.athoracsur.2010.05.059","volume":"90","author":"S Fayoumi","year":"2010","unstructured":"Fayoumi S, Al-Husseini L, Jalil R, Abbasi S. Ectopic pancreatic tissue in the thoracic cavity: report of two cases. Ann Thorac Surg. 2010;90:e25\u20137.","journal-title":"Ann Thorac Surg"},{"key":"2698_CR11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/1749-8090-7-22","volume":"7","author":"S Szabados","year":"2012","unstructured":"Szabados S, L\u00e9n\u00e1rd L, Torn\u00f3czky T, V\u00e1rady E, Verz\u00e1r Z. Ectopic pancreas tissue appearing in a mediastinal cyst. J Cardiothorac Surg. 2012;7:22. https:\/\/doi.org\/10.1186\/1749-8090-7-22. PMID: 22414327; PMCID: PMC3312824.","journal-title":"J Cardiothorac Surg"},{"issue":"2","key":"2698_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.5090\/kjtcs.2012.45.2.131","volume":"45","author":"CS Byun","year":"2012","unstructured":"Byun CS, Park IK, Kim H, Yu W. Ectopic pancreas with hemorrhagic cystic change in the anterior mediastinum. Korean J Thorac Cardiovasc Surg. 2012;45(2):131\u20133. https:\/\/doi.org\/10.5090\/kjtcs.2012.45.2.131. Epub 2012 Apr 3. PMID: 22500286; PMCID: PMC3322185.","journal-title":"Korean J Thorac Cardiovasc Surg"},{"key":"2698_CR13","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/1746-1596-8-176","volume":"8","author":"A Rokach","year":"2013","unstructured":"Rokach A, Izbicki G, Deeb M, Bogot N, Arish N, Hadas-Halperen I, Azulai H, Bohadana A, Golomb E. Ectopic pancreatic pseudocyst and cyst presenting as a cervical and mediastinal mass: case report and review of the literature. Diagn Pathol. 2013;8:176. https:\/\/doi.org\/10.1186\/1746-1596-8-176. PMID: 24152726; PMCID: PMC3817996.","journal-title":"Diagn Pathol"},{"issue":"1","key":"2698_CR14","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/crj.12176","volume":"10","author":"WW Li","year":"2016","unstructured":"Li WW, van Boven WJ, Jurhill RR, Bonta PI, Annema JT, de Mol BA. Ectopic pancreas in a giant mediastinal cyst. Clin Respir J. 2016;10(1):125\u20138. https:\/\/doi.org\/10.1111\/crj.12176. Epub 2014 Aug 13. PMID: 24988877.","journal-title":"Clin Respir J"},{"issue":"4","key":"2698_CR15","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.3892\/ol.2014.1840","volume":"7","author":"L Zhang","year":"2014","unstructured":"Zhang L, Peng LQ, Yu JQ, Yuan HM, Chu ZG, Zeng HJ, Wei B. Ectopic pancreas in the anterior mediastinum: a report of two cases and review of the literature. Oncol Lett. 2014;7(4):1053\u20136. https:\/\/doi.org\/10.3892\/ol.2014.1840. Epub 2014 Jan 29. PMID: 24660035; PMCID: PMC3961199.","journal-title":"Oncol Lett"},{"issue":"7","key":"2698_CR16","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1177\/1066896915596810","volume":"23","author":"HM Koh","year":"2015","unstructured":"Koh HM, Chang JW, Jeong SY, Hyun CL, Kim YS, Jang BG, Maeng YH. Ectopic pancreas presenting as a solid mediastinal mass. Int J Surg Pathol. 2015;23(7):585\u20138. https:\/\/doi.org\/10.1177\/1066896915596810. Epub 2015 Jul 27. PMID: 26215218.","journal-title":"Int J Surg Pathol"},{"issue":"1","key":"2698_CR17","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/s13019-019-0955-2","volume":"14","author":"JM Njem","year":"2019","unstructured":"Njem JM, Ugwu B, Collins J, Emmanuel I, Philip OA, Awodi J. Aberrant pancreatic tissue in a giant mediastinal cyst: an uncommon entity. J Cardiothorac Surg. 2019;14(1):134. https:\/\/doi.org\/10.1186\/s13019-019-0955-2. PMID: 31286963; PMCID: PMC6615225.","journal-title":"J Cardiothorac Surg"},{"key":"2698_CR18","doi-asserted-by":"crossref","unstructured":"Bernal C, Accinelli RA, Fuentes-Rivera G, D\u00edaz J, Ch\u00e1 Vez W, Valdivia E, Morello E, Tafur K, Gayoso O. P\u00e1 ncreas ect\u00f3pico tor\u00e1 cico [Ectopic thoracic pancreas]. Rev Gastroenterol Peru. 2020;40(1):69\u201372. Spanish. PMID: 32369469.","DOI":"10.47892\/rgp.2020.401.1033"},{"key":"2698_CR19","doi-asserted-by":"publisher","unstructured":"Wu L, Lin L, Jiang L, Jiang G. Ectopic pancreas in mediastinum presenting as hemoptysis. Ann Thorac Surg. 2015;100(6):2368. https:\/\/doi.org\/10.1016\/j.athoracsur.2015.08.064. PMID: 26652539.","DOI":"10.1016\/j.athoracsur.2015.08.064"},{"issue":"2","key":"2698_CR20","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3892\/mco.2019.1878","volume":"11","author":"H Zhao","year":"2019","unstructured":"Zhao H, Zhang Z, Li X, Liu J, Zhang H, Chen G, Chen J. Resection of anterior mediastinal ectopic pancreas by right thoracoscopy: a case report. Mol Clin Oncol. 2019;11(2):147\u201350. https:\/\/doi.org\/10.3892\/mco.2019.1878. Epub 2019 Jun 13. PMID: 31316773; PMCID: PMC6604395.","journal-title":"Mol Clin Oncol"},{"issue":"5","key":"2698_CR21","doi-asserted-by":"publisher","first-page":"e367","DOI":"10.1016\/j.athoracsur.2021.07.012","volume":"113","author":"MM Rochefort","year":"2022","unstructured":"Rochefort MM, LeSiege CJ, Shi W, Sholl LM. Ectopic anterior mediastinal pancreas: an unusual case of new onset hemoptysis. Ann Thorac Surg. 2022;113(5):e367\u20139. https:\/\/doi.org\/10.1016\/j.athoracsur.2021.07.012. Epub 2021 Jul 27. PMID: 34329599.","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"2698_CR22","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1007\/s11748-020-01537-6","volume":"69","author":"Y Iijima","year":"2021","unstructured":"Iijima Y, Iwai S, Yamagata A, Motono N, Usuda K, Kumagai M, Takeuchi S, Yamaghishi S, Koizumi K, Uramoto H. Anterior mediastinal ectopic pancreatic cyst incidentally identified by pericarditis: a case report. Gen Thorac Cardiovasc Surg. 2021;69(3):597\u2013600. https:\/\/doi.org\/10.1007\/s11748-020-01537-6. Epub 2020 Nov 2. PMID: 33136258.","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"2698_CR23","doi-asserted-by":"publisher","first-page":"8270516","DOI":"10.1155\/2018\/8270516","volume":"2018","author":"Y Snak","year":"2018","unstructured":"Snak Y, Dwianingsih EK, Sumpono ASB, Panji R, Rahman A, Ghozali A, Amr SS. Mediastinal ectopic pancreas with abundant endocrine cells coexisting with mediastinal cyst and thymic hyperplasia. Case Rep Pathol. 2018;2018:8270516. https:\/\/doi.org\/10.1155\/2018\/8270516. PMID: 29977637; PMCID: PMC5994262.","journal-title":"Case Rep Pathol"},{"issue":"4","key":"2698_CR24","first-page":"249","volume":"45","author":"D von Schweinitz","year":"1990","unstructured":"von Schweinitz D, Wittekind C, Freihorst J. Mediastinaler sequester mit ektopem pankreasgewebe [mediastinal sequestration with ectopic pancreatic tissue]. Z Kinderchir. 1990;45(4):249\u201350. German. PMID.","journal-title":"Z Kinderchir"},{"key":"2698_CR25","doi-asserted-by":"publisher","unstructured":"Fayoumi S, Al-Husseini L, Jalil R, Abbasi S. Ectopic pancreatic tissue in the thoracic cavity: report of two cases. Ann Thorac Surg. 2010;90(2):e25\u20137. https:\/\/doi.org\/10.1016\/j.athoracsur.2010.05.059. PMID: 20667307.","DOI":"10.1016\/j.athoracsur.2010.05.059"},{"key":"2698_CR26","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S1010-7940(98)00168-7","volume":"14","author":"J Wu","year":"1998","unstructured":"Wu J, Chen Y, Ni X. Ectopic pancreas in anterior mediastinal with pseudocyst: one case report. Chin J Thorac Cardiovasc Surg. 1998;14:214.","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"2698_CR27","doi-asserted-by":"publisher","unstructured":"Ehricht A, P\u00fctzschler F, Weissmann K, Klenske M. Ektopes pankreasgewebe in einer mediastinalzyste - eine seltene klinische manifestation [Ectopic pancreatic tissue within a mediastinal cyst\u2013a rare clinical manifestation]. Zentralbl Chir. 2009;134(2):178\u201381. German. https:\/\/doi.org\/10.1055\/s-2008-1076882. Epub 2009 Apr 20. PMID: 19382052.","DOI":"10.1055\/s-2008-1076882"},{"key":"2698_CR28","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/1749-8090-6-118","volume":"6","author":"M Takemura","year":"2011","unstructured":"Takemura M, Yoshida K, Morimura K. Thoracoscopic resection of thoracic esophageal duplication cyst containing ectopic pancreatic tissue in adult. J Cardiothorac Surg. 2011;6:118. https:\/\/doi.org\/10.1186\/1749-8090-6-118. PMID: 21943206; PMCID: PMC3189109.","journal-title":"J Cardiothorac Surg"},{"key":"2698_CR29","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1016\/j.anndiagpath.2011.04.005","volume":"16","author":"P St Romain","year":"2012","unstructured":"St Romain P, Muehlebach G, Damjanov I, Fan F. Adenocarcinoma arising in an ectopic mediastinal pancreas. Ann Diagn Pathol. 2012;16:494\u20137.","journal-title":"Ann Diagn Pathol"},{"issue":"1","key":"2698_CR30","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/den.14189","volume":"34","author":"H Sakurai","year":"2022","unstructured":"Sakurai H, Kanesaka T, Ikezawa K. Mediastinal ectopic pancreas diagnosed by endoscopic ultrasonography-guided fine-needle aspiration. Dig Endosc. 2022;34(1):249. https:\/\/doi.org\/10.1111\/den.14189. Epub 2021 Nov 24. PMID: 34773295.","journal-title":"Dig Endosc"},{"key":"2698_CR31","doi-asserted-by":"publisher","unstructured":"Makhlouf HR, Almeida JL, Sobin LH. Carcinoma in jejunal pancreatic heterotopia. Arch Pathol Lab Med. 1999;123(8):707\u201311. https:\/\/doi.org\/10.5858\/1999-123-0707-CIJPH. PMID: 10420228.","DOI":"10.5858\/1999-123-0707-CIJPH"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02698-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02698-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02698-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,6]],"date-time":"2024-04-06T06:02:03Z","timestamp":1712383323000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02698-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,6]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2698"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02698-8","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,6]]},"assertion":[{"value":"17 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the index patient for publication of this case report and use of images.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"184"}}