{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T10:54:54Z","timestamp":1722941694784},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>For patients with nonischemic dilated cardiomyopathy (NIDCM), the indications for and results of mitral surgery remain controversial. We reviewed a strategy of mitral repair and replacement for clinically relevant secondary mitral regurgitation (MR) in patients with NIDCM.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively reviewed 65 patients with advanced NIDCM (LVEF\u2009&lt;\u200940%) who underwent mitral surgery. Of them, 47 (72%) underwent mitral annuloplasty and 18 (28%) replacement for secondary MR. The primary endpoint was postoperative reduction in indexed LV end-systolic volume (LVESVI).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>At baseline, there was no intergroup difference in LVESVI (123\u2009\u00b1\u200947 vs. 147\u2009\u00b1\u200937 ml\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009=\u20090.055), LVEF (27\u2009\u00b1\u20098% vs. 25\u2009\u00b1\u20096%, <jats:italic>P<\/jats:italic>\u2009=\u20090.41), incidence of severe MR (57% (27\/47) vs. 72% (13\/18), <jats:italic>P<\/jats:italic>\u2009=\u20090.40), or EuroSCORE II score (6.2% vs. 7.6%, <jats:italic>P<\/jats:italic>\u2009=\u20090.90). At 6 months, the annuloplasty group reduced LVESVI to a greater degree than the replacement group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), yielding significantly smaller postoperative LVESVI (96\u2009\u00b1\u200959 vs. 154\u2009\u00b1\u200961 ml\/m<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and better LVEF (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The rates of moderate\/severe recurrent MR were 17% (8\/47) and 0%, respectively. Multivariable analysis demonstrated that mitral annuloplasty (OR 6.10, 95% CI 1.14\u201332.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.035) was significantly associated with postoperative LV reverse remodeling. Cumulative survival was not different between the groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.26).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In patients with NIDCM, mitral annuloplasty reduced LV volume to a greater degree than did mitral replacement. These findings may assist with surgical options for secondary MR associated with NIDCM.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-024-02719-6","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T11:02:03Z","timestamp":1712919723000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Restrictive annuloplasty or replacement on reverse remodeling for nonischemic dilated cardiomyopathy"],"prefix":"10.1186","volume":"19","author":[{"given":"Yusuke","family":"Misumi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuji","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshito","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsubasa","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Taira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Shimamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Miyagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Osaka Cardiovascular Surgery Research (OSCAR) study group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"2719_CR1","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1016\/j.jacc.2010.11.030","volume":"57","author":"M Merlo","year":"2011","unstructured":"Merlo M, Pyxaras SA, Pinamonti B, Barbati G, Di Lenarda A, Sinagra G. 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Since individual patients were not identified in this study, the requirement for informed consent was waived. All baseline and clinical characteristics were obtained from the medical record of patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"201"}}