{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:55:58Z","timestamp":1792806958796,"version":"4.5.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Chylothorax is a postoperative complication in patients with lung cancer. Diet-control approaches have been the mainstay for managing this condition. However, a surgical intervention is needed for the patients if conservative treatment is ineffective. Because of the lack of accurate indicators to assess the prognosis of the postoperative complication at an early stage, the criteria of surgical treatment were not consistent.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We reviewed 2942 patients who underwent pulmonary resection and lymph node dissection for primary lung cancer at our hospital between March 2021 and December 2022. The prognostic implications of clinical indicators were assessed in patients with postoperative chylothorax who were managed with a low-fat diet. Binary logistic regression was used to explore the predictive value of these indicators for patient prognosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Postoperative chylothorax occurred in 108 patients and 79 patients were treated with a low-fat diet management while 29 patients were managed with TPN. In contrast to drainage volume, the pleural effusion triglyceride level after 2 days of low-fat diet exhibited enhanced predictive efficacy in predicting patient prognosis. When the pleural fluid triglyceride level of 1.33 mmol\/L was used as the diagnostic threshold for prognosis, the sensitivity and specificity reached 100% and 80.6%, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The pleural effusion triglyceride level after 2 days of low-fat diet can serve as a valuable prognostic indicator in patients undergoing lung surgery and experiencing chylothorax. This predictive approach will help thoracic surgeons to identify patients with poor prognosis in a timely manner and make decision to perform necessary surgical interventions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-024-02850-4","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T10:02:56Z","timestamp":1718877776000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prognostic significance of Pleural Fluid triglyceride levels based on a low-Fat Diet Management Strategy in patients with Chylothorax following pulmonary resection"],"prefix":"10.1186","volume":"19","author":[{"given":"Hua","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,20]]},"reference":[{"key":"2850_CR1","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.ejcts.2007.04.024","volume":"32","author":"SK Nair","year":"2007","unstructured":"Nair SK, Petko M, Hayward MP. Aetiology and management of chylothorax in adults. Eur J Cardiothorac Surg. 2007;32:362\u201369.","journal-title":"Eur J Cardiothorac Surg"},{"key":"2850_CR2","doi-asserted-by":"publisher","first-page":"303","DOI":"10.5761\/atcs.ra.20-00039","volume":"26","author":"C Chen","year":"2020","unstructured":"Chen C, Wang Z, Hao J, Hao X, Chen J, Chen N, et al. Chylothorax after Lung Cancer surgery: a key factor influencing prognosis and quality of life. Ann Thorac Cardiovasc Surg. 2020;26:303\u201310.","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"2850_CR3","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1055\/s-0030-1270990","volume":"60","author":"H Akin","year":"2012","unstructured":"Akin H, Olcmen A, Isgorucu O, Denizkiran I, Dincer I. Approach to patients with chylothorax complicating pulmonary resection. Thorac Cardiovasc Surg. 2012;60:135\u201339.","journal-title":"Thorac Cardiovasc Surg"},{"key":"2850_CR4","doi-asserted-by":"publisher","first-page":"2875","DOI":"10.1007\/s00268-014-2699-4","volume":"38","author":"CY Liu","year":"2014","unstructured":"Liu CY, Hsu PK, Huang CS, Sun YH, Wu YC, Hsu WH. Chylothorax complicating video-assisted thoracoscopic surgery for non-small cell lung cancer. World J Surg. 2014;38:2875\u201381.","journal-title":"World J Surg"},{"key":"2850_CR5","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1055\/s-0040-1710071","volume":"68","author":"F Petrella","year":"2020","unstructured":"Petrella F, Casiraghi M, Radice D, Bertolaccini L, Spaggiari L. Treatment of Chylothorax after Lung Resection: indications, timing, and outcomes. Thorac Cardiovasc Surg. 2020;68:520\u201324.","journal-title":"Thorac Cardiovasc Surg"},{"key":"2850_CR6","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1055\/s-2003-45423","volume":"51","author":"CA Kutlu","year":"2003","unstructured":"Kutlu CA, Sayar A, Olgac G, Akin H, Olcmen A, A Bedirhan M, et al. Chylothorax: a complication following lung resection in patients with NSCLC - chylothorax following lung resection. Thorac Cardiovasc Surg. 2003;51:342\u201345.","journal-title":"Thorac Cardiovasc Surg"},{"key":"2850_CR7","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/s00595-015-1183-6","volume":"46","author":"S Uchida","year":"2016","unstructured":"Uchida S, Suzuki K, Hattori A, Takamochi K, Oh S. Surgical intervention strategy for postoperative chylothorax after lung resection. Surg Today. 2016;46:197\u2013202.","journal-title":"Surg Today"},{"key":"2850_CR8","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1067\/mtc.2002.124386","volume":"124","author":"K Shimizu","year":"2002","unstructured":"Shimizu K, Yoshida J, Nishimura M, Takamochi K, Nakahara R, Nagai K. Treatment strategy for chylothorax after pulmonary resection and lymph node dissection for lung cancer. J Thorac Cardiovasc Surg. 2002;124:499\u2013502.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2850_CR9","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s13019-022-01758-1","volume":"17","author":"Y Yasuura","year":"2022","unstructured":"Yasuura Y, Konno H, Hayakawa T, Terada Y, Mizuno K, Kayata H, et al. Chylothorax after pulmonary resection and lymph node dissection for primary lung cancer; retrospective observational study. J Cardiothorac Surg. 2022;17:11.","journal-title":"J Cardiothorac Surg"},{"key":"2850_CR10","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.athoracsur.2013.10.065","volume":"97","author":"HJ Cho","year":"2014","unstructured":"Cho HJ, Kim DK, Lee GD, Sim HJ, Chio SH, Kim HR, et al. Chylothorax complicating pulmonary resection for lung cancer: effective management and pleurodesis. Ann Thorac Surg. 2014;97:408\u201313.","journal-title":"Ann Thorac Surg"},{"key":"2850_CR11","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1097\/00003246-198501000-00013","volume":"13","author":"L Teba","year":"1985","unstructured":"Teba L, Dedhia HV, Bowen R, Alexander JC. Chylothorax review. Crit Care Med. 1985;13:49\u201352.","journal-title":"Crit Care Med"},{"key":"2850_CR12","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/j.jtcvs.2013.04.015","volume":"146","author":"T Takuwa","year":"2013","unstructured":"Takuwa T, Yoshida J, Ono S, Hishida T, Nishimura M, Aokage K, et al. Low-fat diet management strategy for chylothorax after pulmonary resection and lymph node dissection for primary lung cancer. J Thorac Cardiovasc Surg. 2013;146:571\u20134.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2850_CR13","doi-asserted-by":"crossref","unstructured":"Maldonado F, Hawkins FJ, Daniels CE, Doerr CH, Decker PA, Ryu JH. Pleural fluid characteristics of chylothorax. Mayo Clin Proc. 2009;84(2):129\u2009\u2013\u200933.","DOI":"10.4065\/84.2.129"},{"key":"2850_CR14","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jtcvs.2007.08.066","volume":"135","author":"RJ Cerfolio","year":"2008","unstructured":"Cerfolio RJ, Bryant AS. Results of a prospective algorithm to remove chest tubes after pulmonary resection with high output. J Thorac Cardiovasc Surg. 2008;135:269\u201373.","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02850-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02850-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02850-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T10:08:20Z","timestamp":1718878100000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02850-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,20]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2850"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02850-4","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,20]]},"assertion":[{"value":"26 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Yantai Yuhuangding Hospital Research Ethics Committee in 2023 (Approval No. 2023\u2009\u2212\u2009381) and the need for individual informed consent was waived.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"337"}}