{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:25:50Z","timestamp":1791653150467,"version":"4.3.4"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>In a sedated patient, airway compression by a large mediastinal mass can cause acute fatal cardiopulmonary arrest. Extracorporeal membrane oxygenation (ECMO) has been investigated to protect the airway and provided cardiopulmonary stability. The use of ECMO in the management of mediastinal masses was reported, however, the management complicated by cardiopulmonary arrest is poorly documented.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>32-year-old female presented with acute onset of left arm swelling and subacute onset of dry cough. Further investigation showed a deep venous thrombosis in left upper extremity as well as a large mediastinal mass. She underwent mediastinoscopy with biopsy of the mass which was complicated by cardiopulmonary arrest secondary to airway obstruction by the mediastinal mass. Venoarterial ECMO was initiated, while concurrently treating with a chemotherapy. The mediastinal mass responded to the chemotherapy and reduced in size during 2 days of ECMO support. She was extubated successfully and decannulated after 2 days of ECMO and discharged later.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Extracorporeal membrane oxygenation can serve as a viable strategy to facilitate cardiopulmonary support while concurrently treating the tumor with chemotherapy, ultimately allowing for the recovery of cardiopulmonary function, and achieving satisfactory outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13019-024-02918-1","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T06:02:37Z","timestamp":1719381757000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Extracorporeal membrane oxygenation bridging for chemotherapy in obstructing mediastinal mass after cardiopulmonary arrest"],"prefix":"10.1186","volume":"19","author":[{"given":"Daniel","family":"Wilkinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enoch","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Samy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chikashi","family":"Nakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"2918_CR1","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/S0889-8537(05)70247-9","volume":"19","author":"S Narang","year":"2001","unstructured":"Narang S, Harte BH, Body SC. Anesthesia for patients with a mediastinal mass. Anesthesiol Clin North Am. 2001;19:559\u201379.","journal-title":"Anesthesiol Clin North Am"},{"key":"2918_CR2","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1177\/021849230601400224","volume":"14","author":"VT Chao","year":"2006","unstructured":"Chao VT, Lim DW, Tao M, Thirugnanam A, Koong HN, Lim CH. Tracheobronchial obstruction as a result of mediastinal mass. Asian Cardiovasc Thorac Ann. 2006;14:e17\u20138.","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"2918_CR3","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/01.PCC.0000235247.10880.F8","volume":"7","author":"TK Frey","year":"2006","unstructured":"Frey TK, Chopra A, Lin RJ, Levy RJ, Gruber P, Rheingold SR, et al. A child with anterior mediastinal mass supported with veno-arterial extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2006;7:479\u201381.","journal-title":"Pediatr Crit Care Med"},{"key":"2918_CR4","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1097\/LBR.0000000000000435","volume":"25","author":"BT Nokes","year":"2018","unstructured":"Nokes BT, Vaszar L, Jahanyar J, Swanson KL. VV-ECMO-Assisted high-risk endobronchial stenting as rescue for asphyxiating Mediastinal Mass. J Bronchol Interv Pulmonol. 2018;25:144\u20137.","journal-title":"J Bronchol Interv Pulmonol"},{"key":"2918_CR5","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1186\/s40792-018-0517-1","volume":"4","author":"E Booka","year":"2018","unstructured":"Booka E, Kitano M, Nakano Y, Mihara K, Nishiya S, Nishiyama R, et al. Life-threatening giant esophageal neurofibroma with severe tracheal stenosis: a case report. Surg Case Rep. 2018;4:107.","journal-title":"Surg Case Rep"},{"key":"2918_CR6","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s12055-020-01077-x","volume":"37","author":"K Ramanathan","year":"2021","unstructured":"Ramanathan K, Leow L, Mithiran H. ECMO and adult mediastinal masses. Indian J Thorac Cardiovasc Surg. 2021;37:338\u201343.","journal-title":"Indian J Thorac Cardiovasc Surg"},{"key":"2918_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2141.2004.05094.x","volume":"127","author":"MS Cairo","year":"2004","unstructured":"Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol. 2004;127:3\u201311.","journal-title":"Br J Haematol"},{"key":"2918_CR8","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/j.jcrc.2012.02.013","volume":"27","author":"K Shekar","year":"2012","unstructured":"Shekar K, Fraser JF, Smith MT, Roberts JA. Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation. J Crit Care. 2012;27:741.","journal-title":"J Crit Care"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02918-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02918-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02918-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T06:10:32Z","timestamp":1719382232000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02918-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,26]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2918"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02918-1","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,26]]},"assertion":[{"value":"6 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Albany Med Office of Research Affairs confirmed this case report did not require review or approval by IRB as long as consent for the study was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"382"}}