{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T04:30:53Z","timestamp":1724473853701},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T00:00:00Z","timestamp":1722816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human fibrinogen (FIB) has been clinically proven to be considerably effective for the treatment of postoperative bleeding, with reported cases of allergic reactions to human FIB being rare. Here, we report a case of an anaphylactic shock in 27-year-old patients with rheumatic heart valve disease who received a human FIB infusion during mitral valve replacement, aortic valve replacement, and tricuspid valve-shaping surgery. The patients showed generalised profuse sweating, a barely noticeable skin rash, faint pulse, systolic pressure\u2009&lt;\u200950 mmHg, and a heart rate of 71 beats\/min. We share insights from a case of severe allergy to human FIB infusion during cardiac surgery, through which we have gained experience in the processes of diagnosing and treating. This report aims to provide a preliminary summary of the characteristics of this case to serve as a reference for fellow clinicians.<\/jats:p>","DOI":"10.1186\/s13019-024-02956-9","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T08:03:29Z","timestamp":1722845009000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A case of anaphylactic shock to human fibrinogen infusion during cardiac surgery"],"prefix":"10.1186","volume":"19","author":[{"given":"Chun","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weipeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"issue":"1","key":"2956_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.iac.2021.09.001","volume":"42","author":"AG Bagos-Estevez","year":"2022","unstructured":"Bagos-Estevez AG, Ledford DK, Anaphylaxis. Definition, Epidemiology, Diagnostic challenges, Grading System. Immunol Allergy Clin North Am. 2022;42(1):1\u201311. https:\/\/doi.org\/10.1016\/j.iac.2021.09.001.","journal-title":"Immunol Allergy Clin North Am"},{"issue":"2","key":"2956_CR2","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.anai.2023.05.010","volume":"131","author":"DV Wallace","year":"2023","unstructured":"Wallace DV. Knowledge gaps in the diagnosis and management of anaphylaxis. Ann Allergy Asthma Immunol. 2023;131(2):151\u201369. https:\/\/doi.org\/10.1016\/j.anai.2023.05.010.","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"01","key":"2956_CR3","first-page":"175","volume":"39","author":"MY Han","year":"2018","unstructured":"Han MY, Wang QC. A case report of skin-induced suspected allergic reaction using dexmedetomidine-containing needle acupuncture. J Med Forum. 2018;39(01):175\u20136.","journal-title":"J Med Forum"},{"issue":"02","key":"2956_CR4","doi-asserted-by":"publisher","first-page":"214","DOI":"10.3969\/j.issn.2095-8552.2022.02.027","volume":"50","author":"L Meng","year":"2022","unstructured":"Meng L, Huang M, Shi AW, et al. The efficacy and safety of human fibrinogen in the treatment of postpartum hemorrhage. Chin J Clin. 2022;50(02):214\u20137. https:\/\/doi.org\/10.3969\/j.issn.2095-8552.2022.02.027.","journal-title":"Chin J Clin"},{"key":"2956_CR5","unstructured":"Pharmacopoeia Commission of People\u2019s Republic of China, Pharmacopoeia of People\u2019s Republic of China [S]. 2015 edition (3 parts). Beijing: China Medical Science Press; 2015. pp. 274\u20135."},{"issue":"6","key":"2956_CR6","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.3390\/ijms19061597","volume":"19","author":"GL Tiscia","year":"2018","unstructured":"Tiscia GL, Margaglione M. Human fibrinogen: Molecular and genetic aspects of congenital disorders. Int J Mol Sci. 2018;19(6):1597. https:\/\/doi.org\/10.3390\/ijms19061597.","journal-title":"Int J Mol Sci"},{"issue":"8","key":"2956_CR7","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1002\/rth2.12433","volume":"4","author":"J Lasky","year":"2020","unstructured":"Lasky J, Teitel J, Wang M, et al. Fibrinogen concentrate for bleeding in patients with congenital fibrinogen deficiency: observational study of efficacy and safety for prophylaxis and treatment. Res Pract Thromb Haemost. 2020;4(8):1313\u201323. https:\/\/doi.org\/10.1002\/rth2.12433.","journal-title":"Res Pract Thromb Haemost"},{"issue":"5","key":"2956_CR8","doi-asserted-by":"publisher","first-page":"e0126692","DOI":"10.1371\/journal.pone.0126692","volume":"10","author":"G Erdoes","year":"2015","unstructured":"Erdoes G, Gerster G, Colucci G, Kaiser H, Alberio L, Eberle B. Prediction of Post-weaning Fibrinogen Status during Cardiopulmonary Bypass: an observational study in 110 patients. PLoS ONE. 2015;10(5):e0126692.","journal-title":"PLoS ONE"},{"issue":"5","key":"2956_CR9","first-page":"66","volume":"25","author":"Q Liu","year":"2019","unstructured":"Liu Q, Li M, Cheng H. A case report of allergic reaction to human fibrinogen infusion in neonates. J Pediatr Pharm. 2019;25(5):66.","journal-title":"J Pediatr Pharm"},{"issue":"4","key":"2956_CR10","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1111\/jth.14727","volume":"18","author":"T Lissitchkov","year":"2020","unstructured":"Lissitchkov T, Madan B, Djambas Khayat C, et al. Fibrinogen concentrate for treatment of bleeding and surgical prophylaxis in congenital fibrinogen deficiency patients. J Thromb Haemost. 2020;18(4):815\u201324. https:\/\/doi.org\/10.1111\/jth.14727.","journal-title":"J Thromb Haemost"},{"key":"2956_CR11","doi-asserted-by":"publisher","first-page":"110814","DOI":"10.1016\/j.forsciint.2021.110814","volume":"323","author":"N Heldring","year":"2021","unstructured":"Heldring N, Kahn L, Zilg B. Fatal anaphylactic shock: a review of postmortem biomarkers and diagnostics. Forensic Sci Int. 2021;323:110814. https:\/\/doi.org\/10.1016\/j.forsciint.2021.110814.","journal-title":"Forensic Sci Int"},{"issue":"1","key":"2956_CR12","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.iac.2021.09.002","volume":"42","author":"MM Pitlick","year":"2022","unstructured":"Pitlick MM, Volcheck GW. Perioperative Anaphylaxis. Immunol Allergy Clin North Am. 2022;42(1):145\u201359. https:\/\/doi.org\/10.1016\/j.iac.2021.09.002.","journal-title":"Immunol Allergy Clin North Am"},{"issue":"15","key":"2956_CR13","doi-asserted-by":"publisher","first-page":"7785","DOI":"10.3390\/ijms22157785","volume":"22","author":"SMT Nguyen","year":"2021","unstructured":"Nguyen SMT, Rupprecht CP, Haque A, et al. Mechanisms governing Anaphylaxis: inflammatory cells, mediators, endothelial gap junctions and Beyond. Int J Mol Sci. 2021;22(15):7785. https:\/\/doi.org\/10.3390\/ijms22157785.","journal-title":"Int J Mol Sci"},{"issue":"3","key":"2956_CR14","first-page":"273","volume":"42","author":"M Yang","year":"2022","unstructured":"Yang M, Liu WC. Prevention and treatment of capillary vascular leakage in anaphylactic shock. Chin J Crit Care Med. 2022;42(3):273\u20136.","journal-title":"Chin J Crit Care Med"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02956-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02956-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02956-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T08:08:09Z","timestamp":1722845289000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02956-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,5]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2956"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02956-9","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,5]]},"assertion":[{"value":"23 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This case report was approved by the Ethics Committee of Shanghai DeltaHealth Hospital and the patient signed the informed consent form.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"480"}}