{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:25:05Z","timestamp":1772166305088,"version":"3.50.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Aortic regurgitation with dilated annulus presents a technical challenge for conventional transcatheter aortic valve implantation (TAVI) procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report a case of an 84-year-old frail patient with a history of breathlessness found to have severe aortic regurgitation and moderately impaired left ventricular systolic function. The patient underwent a successful TAVI procedure using the XL-Myval 32\u00a0mm transcatheter heart valve (THV) via an anterior right mini-thoracotomy with a direct aortic approach. The patient recovered well post-operatively with good hemodynamic resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This first in human case highlights the efficacy and potential of applying innovative approaches, such as the new sizes of Myval THV and direct aortic access via anterior right mini thoracotomy, in addressing challenging anatomical variations in TAVI procedures with good outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-024-02982-7","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T04:03:35Z","timestamp":1724990615000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Direct aortic TAVI via anterior right mini-thoracotomy using 32\u00a0mm myval for pure aortic regurgitation"],"prefix":"10.1186","volume":"19","author":[{"given":"Firas","family":"Aljanadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"McNeilly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganesh","family":"Manoharan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"McNiece","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reuben","family":"Jeganathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"2982_CR1","doi-asserted-by":"crossref","unstructured":"1. - Thielmann M, Tsagakis K, El Gabry M, Jakob H, Wendt D. Transcatheter aortic valve implantation (TAVI) in patients with aortic regurgitation. Ann Cardiothorac Surg. (2017) 6:558\u201360. 10.21037\/acs.2017.09.16","DOI":"10.21037\/acs.2017.09.16"},{"key":"2982_CR2","doi-asserted-by":"crossref","unstructured":"2. - Schneeberger Y, Seiffert M, Schaefer A, Bhadra OD, Schofer N, Pecha S, Westermann D, Blankenberg S, Reichenspurner H, Conradi L. TAVI for Pure Non-calcified Aortic Regurgitation Using a Self-Expandable Transcatheter Heart Valve. Front Cardiovasc Med. 2022 Jan 25;8:743579. doi: 10.3389\/fcvm.2021.743579. PMID: 35146003; PMCID: PMC8823702.","DOI":"10.3389\/fcvm.2021.743579"},{"key":"2982_CR3","doi-asserted-by":"crossref","unstructured":"3. - Elkoumy A, Terkelsen CJ, Abdelshafy M, Ellert-Gregersen J, Elzomor H, Thim T, Serruys PW, Soliman O and Nissen H (2022) Case report: Transcatheter aortic valve replacement in a large bicuspid anatomy using the XL-Myval 32\u00a0mm. Front. Cardiovasc. Med. 9:1045280. doi: 10.3389\/fcvm.2022.1045280","DOI":"10.3389\/fcvm.2022.1045280"},{"key":"2982_CR4","doi-asserted-by":"crossref","unstructured":"4. - Hamieh M, Nassereddine Z, Moussa M, Al Ali F, Dbouk M, Saab M. Transcatheter aortic valve implantation for aortic regurgitation in HeartMate II supported patient using Myval THV: a case report. Oxf Med Case Reports. 2023 Oct 23;2023(10):omad086. doi: 10.1093\/omcr\/omad086. PMID: 37881260; PMCID: PMC10597617.","DOI":"10.1093\/omcr\/omad086"},{"key":"2982_CR5","doi-asserted-by":"crossref","unstructured":"5. - Seth A, Kumar V, Singh VP, Kumar D, Varma P, Rastogi V. Myval: A Novel Transcatheter Heart Valve for the Treatment of Severe Aortic Stenosis. Interv Cardiol. 2023 Apr 10;18:e12. doi: 10.15420\/icr.2020.32. PMID: 37398875; PMCID: PMC10311401.","DOI":"10.15420\/icr.2020.32"},{"key":"2982_CR6","doi-asserted-by":"crossref","unstructured":"6. - M. Branny, et al., Alternative access routes for transcatheter aortic valve implantation (TAVI), Cor et Vasa 59 (2017) e10\u2013e16. doi.org\/10.1016\/j.crvasa.2017.01.024","DOI":"10.1016\/j.crvasa.2017.01.024"},{"key":"2982_CR7","doi-asserted-by":"crossref","unstructured":"7. - Vohra HA, Salmasi MY, Mohamed F, Shehata M, Bahrami B, Caputo M, Deshpande R, Bapat V, Bahrami T, Birdi I, Zacharias J. Consensus statement on aortic valve replacement via an anterior right minithoracotomy in the UK healthcare setting. Open Heart. 2023 Mar;10(1):e002194. doi: 10.1136\/openhrt-2022-002194. PMID: 37001910; PMCID: PMC10069572.","DOI":"10.1136\/openhrt-2022-002194"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02982-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-024-02982-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-024-02982-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T04:08:00Z","timestamp":1724990880000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardiothoracicsurgery.biomedcentral.com\/articles\/10.1186\/s13019-024-02982-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,30]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2982"],"URL":"https:\/\/doi.org\/10.1186\/s13019-024-02982-7","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4263167\/v1","asserted-by":"object"}]},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,30]]},"assertion":[{"value":"13 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval is N\/A, however, an informed Consent to participate form is completed and signed by the patient and available on request.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"This was included in the consent form signed by the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"506"}}