{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T01:26:41Z","timestamp":1786670801121,"version":"build-2736575974"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:00:00Z","timestamp":1786665600000},"content-version":"vor","delay-in-days":66,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      Mitral valve repair (MVr) promotes left ventricular (LV) reverse remodelling, and subsequent reduction in LV diameters and volumes. The effectiveness of different MVr techniques,\n                      <jats:italic>Resect<\/jats:italic>\n                      (leaflet resection) and\n                      <jats:italic>Respect<\/jats:italic>\n                      (leaflet preservation) remains debated. This study aimed to investigate the impact of\n                      <jats:italic>\u2018Resect\u2019<\/jats:italic>\n                      and \u2018\n                      <jats:italic>Respect\u2019<\/jats:italic>\n                      techniques on LV reverse remodelling, primarily assessed by changes in indexed LV end-systolic diameter (ILVESD) post-MVr.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data were drawn from the UK Mini Mitral Trial, which randomised 330 patients to MVr via mini-thoracotomy or median-sternotomy. This subanalysis included patients with isolated posterior leaflet prolapse, who had undergone MVr via\n                      <jats:italic>Resect<\/jats:italic>\n                      or\n                      <jats:italic>Respect<\/jats:italic>\n                      techniques. Transthoracic echocardiography was performed pre-operatively and at 12 and 52 weeks post-operatively, with all studies analysed by a core laboratory. Linear mixed-effects models compared changes in indexed LV measurements between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This subanalysis included 175 patients (36\n                      <jats:italic>Resect<\/jats:italic>\n                      and 139\n                      <jats:italic>Respect)<\/jats:italic>\n                      . Annuloplasty was performed in all but one repair. We found no significant difference between groups in recurrent MR severity at 52 weeks postoperatively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.31). Both groups had significant improvement in ILVESD by 52 weeks (mean change from baseline\u2009\u2212\u20095.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no difference between groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.24). Both techniques led to significant improvements in indexed end-diastolic LV volumes and diameters, decreasing from baseline to 12 and 52 weeks. However, LV end-systolic volumes and diameters increased at 12 weeks before decreasing by 52 weeks postoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      No significant differences in LV reverse remodelling between\n                      <jats:italic>Resect<\/jats:italic>\n                      and\n                      <jats:italic>Respect<\/jats:italic>\n                      techniques. Both can be recommended to surgeons. Longer follow-up is needed.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13019-026-04060-6","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T14:26:14Z","timestamp":1781015174000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of leaflet resection versus leaflet preservation on left ventricular reverse remodelling after mitral valve repair: insights from the UK mini mitral trial"],"prefix":"10.1186","volume":"21","author":[{"given":"Eteesha","family":"Rao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Bayliss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janelle M.","family":"Wagnild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enoch","family":"Akowuah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"issue":"9672","key":"4060_CR1","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1016\/S0140-6736(09)60692-9","volume":"373","author":"M Enriquez-Sarano","year":"2009","unstructured":"Enriquez-Sarano M, Akins CW, Vahanian A. 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