{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:09:00Z","timestamp":1792804140946,"version":"4.5.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":44,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Cardiothorac Surg"],"DOI":"10.1186\/s13019-026-04142-5","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:05:41Z","timestamp":1776704741000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of preoperative respiratory prehabilitation on cardiopulmonary function in patients undergoing lung resection for non-small cell lung cancer: a randomized controlled trial"],"prefix":"10.1186","volume":"21","author":[{"given":"Feiyan","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengxu","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caina","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinghui","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyue","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"4142_CR1","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1056\/NEJMoa2212083","volume":"388","author":"N Altorki","year":"2023","unstructured":"Altorki N, Wang X, Kozono D, Watt C, Landrenau R, Wigle D, et al. Lobar or sublobar resection for peripheral stage IA non-small-cell lung cancer. N Engl J Med. 2023;388:489\u201398. https:\/\/doi.org\/10.1056\/NEJMoa2212083.","journal-title":"N Engl J Med"},{"key":"4142_CR2","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1016\/S0140-6736(21)02333-3","volume":"399","author":"H Saji","year":"2022","unstructured":"Saji H, Okada M, Tsuboi M, Nakajima R, Suzuki K, Aokage K, et al. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802\/WJOG4607L): A multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial. Lancet Lond Engl. 2022;399:1607\u201317. https:\/\/doi.org\/10.1016\/S0140-6736(21)02333-3.","journal-title":"Lancet Lond Engl"},{"key":"4142_CR3","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1183\/09031936.00184308","volume":"34","author":"A Brunelli","year":"2009","unstructured":"Brunelli A, Charloux A, Bolliger CT, Rocco G, Sculier J-P, Varela G, et al. ERS\/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J. 2009;34:17\u201341. https:\/\/doi.org\/10.1183\/09031936.00184308.","journal-title":"Eur Respir J"},{"key":"4142_CR4","doi-asserted-by":"publisher","first-page":"S2593","DOI":"10.21037\/jtd.2018.08.18","volume":"10","author":"D Sanchez-Lorente","year":"2018","unstructured":"Sanchez-Lorente D, Navarro-Ripoll R, Guzman R, Moises J, Gimeno E, Boada M, et al. Prehabilitation in thoracic surgery. J Thorac Dis. 2018;10:S2593\u2013600. https:\/\/doi.org\/10.21037\/jtd.2018.08.18.","journal-title":"J Thorac Dis"},{"key":"4142_CR5","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1186\/s12885-023-11254-x","volume":"23","author":"K Wade-Mcbane","year":"2023","unstructured":"Wade-Mcbane K, King A, Urch C, Jeyasingh-Jacob J, Milne A, Boutillier CL. Prehabilitation in the lung cancer pathway: A scoping review. BMC Cancer. 2023;23:747. https:\/\/doi.org\/10.1186\/s12885-023-11254-x.","journal-title":"BMC Cancer"},{"key":"4142_CR6","doi-asserted-by":"publisher","first-page":"3255","DOI":"10.1053\/j.jvca.2021.02.049","volume":"35","author":"EM Minnella","year":"2021","unstructured":"Minnella EM, Baldini G, Quang ATL, Bessissow A, Spicer J, Carli F. Prehabilitation in thoracic cancer surgery: From research to standard of care. J Cardiothorac Vasc Anesth. 2021;35:3255\u201364. https:\/\/doi.org\/10.1053\/j.jvca.2021.02.049.","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"4142_CR7","doi-asserted-by":"publisher","unstructured":"Xinxing SUN, Yalin WANG, Wang LV, Linhai ZHU. Application Research of Narrative Care to the Management of Symptom Clusters and Post-traumatic Growth in Patients Undergoing Lung Cancer Surgery. Chin J Lung Cancer. 2025;28:40\u20136. https:\/\/doi.org\/10.3779\/j.issn.1009-3419.2024.102.44","DOI":"10.3779\/j.issn.1009-3419.2024.102.44"},{"key":"4142_CR8","doi-asserted-by":"publisher","first-page":"CD012020","DOI":"10.1002\/14651858.CD012020.pub3","volume":"9","author":"C Granger","year":"2022","unstructured":"Granger C, Cavalheri V. Preoperative exercise training for people with non-small cell lung cancer. Cochrane Database Syst Rev. 2022;9:CD012020. https:\/\/doi.org\/10.1002\/14651858.CD012020.pub3.","journal-title":"Cochrane Database Syst Rev"},{"key":"4142_CR9","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.lungcan.2011.05.011","volume":"74","author":"R Benzo","year":"2011","unstructured":"Benzo R, Wigle D, Novotny P, Wetzstein M, Nichols F, Shen RK, et al. Preoperative pulmonary rehabilitation before lung cancer resection: Results from two randomized studies. Lung Cancer Amsterdam Neth. 2011;74:441\u20135. https:\/\/doi.org\/10.1016\/j.lungcan.2011.05.011.","journal-title":"Lung Cancer Amsterdam Neth"},{"key":"4142_CR10","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.apmr.2012.08.206","volume":"94","author":"MT Morano","year":"2013","unstructured":"Morano MT, Ara\u00fajo AS, Nascimento FB, da Silva GF, Mesquita R, Pinto JS, et al. Preoperative pulmonary rehabilitation versus chest physical therapy in patients undergoing lung cancer resection: A pilot randomized controlled trial. Arch Phys Med Rehabil. 2013;94:53\u20138. https:\/\/doi.org\/10.1016\/j.apmr.2012.08.206.","journal-title":"Arch Phys Med Rehabil"},{"key":"4142_CR11","doi-asserted-by":"publisher","unstructured":"Xu X, Cheung DST, Smith R, Lai AYK, Lin C-C. The effectiveness of pre- and post-operative rehabilitation for lung cancer: A systematic review and meta-analysis on postoperative pulmonary complications and length of hospital stay. Clin Rehabil. Volume 36. SAGE Publications Ltd STM; 2022. pp. 172\u201389. https:\/\/doi.org\/10.1177\/02692155211043267.","DOI":"10.1177\/02692155211043267"},{"key":"4142_CR12","doi-asserted-by":"publisher","first-page":"641","DOI":"10.3760\/cma.j.cn112434-20250424-00128","volume":"41","author":"Chinese Anti-Cancer Association Committee of Pulmonary Tumor Integrated Rehabilitation, China International Exchange and Promotive Association for Medical and Health Care - Lung Cancer Prevention and Control Branch, China International Exchange and Promotive Association for Medical and Health Care - Thoracic Surgery Branch, Zhejiang Medical Doctor Association Chapter of Thoracic Surgeons","year":"2025","unstructured":"Chinese Anti-Cancer Association Committee of Pulmonary Tumor Integrated Rehabilitation, China International Exchange and Promotive Association for Medical and Health Care - Lung Cancer Prevention and Control Branch, China International Exchange and Promotive Association for Medical and Health Care - Thoracic Surgery Branch, Zhejiang Medical Doctor Association Chapter of Thoracic Surgeons. Chinese expert consensus on digital diagnosis and treatment management in thoracic surgery perioperative care(2025). Chin J Thorac Cardiovasc Surg. 2025;41:641\u201351. https:\/\/doi.org\/10.3760\/cma.j.cn112434-20250424-00128.","journal-title":"Chin J Thorac Cardiovasc Surg"},{"key":"4142_CR13","doi-asserted-by":"publisher","first-page":"1600","DOI":"10.1016\/j.athoracsur.2020.11.022","volume":"112","author":"V Ferreira","year":"2021","unstructured":"Ferreira V, Minnella EM, Awasthi R, Gamsa A, Ferri L, Mulder D, et al. Multimodal prehabilitation for lung cancer surgery: A randomized controlled trial. Ann Thorac Surg. 2021;112:1600\u20138. https:\/\/doi.org\/10.1016\/j.athoracsur.2020.11.022.","journal-title":"Ann Thorac Surg"},{"key":"4142_CR14","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1093\/icvts\/ivx141","volume":"25","author":"Y Lai","year":"2017","unstructured":"Lai Y, Su J, Qiu P, Wang M, Zhou K, Tang Y, et al. Systematic short-term pulmonary rehabilitation before lung cancer lobectomy: a randomized trial. Interact CardioVasc Thorac Surg. 2017;25:476\u201383. https:\/\/doi.org\/10.1093\/icvts\/ivx141.","journal-title":"Interact CardioVasc Thorac Surg"},{"key":"4142_CR15","doi-asserted-by":"publisher","first-page":"544","DOI":"10.21037\/atm.2019.09.151","volume":"7","author":"Y Lai","year":"2019","unstructured":"Lai Y, Wang X, Zhou K, Su J, Che G. Impact of one-week preoperative physical training on clinical outcomes of surgical lung cancer patients with limited lung function: a randomized trial. Ann Transl Med. 2019;7:544. https:\/\/doi.org\/10.21037\/atm.2019.09.151.","journal-title":"Ann Transl Med"},{"key":"4142_CR16","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1136\/thoraxjnl-2021-217242","volume":"77","author":"F-E Gravier","year":"2022","unstructured":"Gravier F-E, Smondack P, Prieur G, Medrinal C, Combret Y, Muir J-F, et al. Effects of exercise training in people with non-small cell lung cancer before lung resection: a systematic review and meta-analysis. Thorax. 2022;77:486\u201396. https:\/\/doi.org\/10.1136\/thoraxjnl-2021-217242.","journal-title":"Thorax"},{"key":"4142_CR17","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3390\/biomed6010008","volume":"6","author":"S Andreadou","year":"2026","unstructured":"Andreadou S, Tanti A, Gkiliri F, Chatzikonstantinou K, Vatista E, Christakou A. The role of pulmonary rehabilitation programs in patients with lung cancer: a narrative review. BioMed. Multidisciplinary Digit Publishing Inst. 2026;6:8. https:\/\/doi.org\/10.3390\/biomed6010008.","journal-title":"Multidisciplinary Digit Publishing Inst"}],"container-title":["Journal of Cardiothoracic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13019-026-04142-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-026-04142-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13019-026-04142-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:52:00Z","timestamp":1780444320000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13019-026-04142-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,20]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4142"],"URL":"https:\/\/doi.org\/10.1186\/s13019-026-04142-5","relation":{},"ISSN":["1749-8090"],"issn-type":[{"value":"1749-8090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,20]]},"assertion":[{"value":"6 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the institutional review board of The First Affiliated Hospital, Zhejiang University School of Medicine (approval No. IIT20240772B-R1). The trial was registered in the Medical Research Registration and Record Information System of the National Healthcare Security Information Platform (registration No. MR-33-25-019022). Written informed consent was obtained from all individual participants included in the study. The study was conducted in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"323"}}