{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:20:47Z","timestamp":1791984047360,"version":"4.4.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Orphanet J Rare Dis"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/s13023-014-0144-2","type":"journal-article","created":{"date-parts":[[2014,12,18]],"date-time":"2014-12-18T20:22:09Z","timestamp":1418934129000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Ventricular septal defect"],"prefix":"10.1186","volume":"9","author":[{"given":"Diane E","family":"Spicer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao H","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Co-Vu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F Jay","family":"Fricker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,12,19]]},"reference":[{"key":"144_CR1","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1016\/0002-9149(84)90662-3","volume":"53","author":"WC Roberts","year":"1984","unstructured":"Roberts WC: The 2 most common congenital heart diseases [Editorial]. Am J Cardiol. 1984, 53: 1198-10.1016\/0002-9149(84)90662-3.","journal-title":"Am J Cardiol"},{"key":"144_CR2","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1161\/01.CIR.43.3.323","volume":"43","author":"SC Mitchell","year":"1971","unstructured":"Mitchell SC, Korones SB, Berendes HW: Congenital heart disease in 56,109 births. Incidence and natural history. Circulation. 1971, 43: 323-332. 10.1161\/01.CIR.43.3.323.","journal-title":"Circulation"},{"key":"144_CR3","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1136\/hrt.43.3.332","volume":"43","author":"B Soto","year":"1980","unstructured":"Soto B, Becker AE, Moulaert AJ, Lie JT, Anderson RH: Classification of ventricular septal defects. Br Heart J. 1980, 43: 332-343. 10.1136\/hrt.43.3.332.","journal-title":"Br Heart J"},{"key":"144_CR4","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.1016\/0002-9149(83)90660-4","volume":"51","author":"H Capelli","year":"1983","unstructured":"Capelli H, Andrade JL, Somerville J: Classification of the site of ventricular septal defect by 2-dimensional echocardiography. Am J Cardiol. 1983, 51: 1474-1480. 10.1016\/0002-9149(83)90660-4.","journal-title":"Am J Cardiol"},{"issue":"Suppl 4","key":"144_CR5","doi-asserted-by":"publisher","first-page":"S25","DOI":"10.1016\/S0003-4975(99)01270-9","volume":"69","author":"JP Jacobs","year":"2000","unstructured":"Jacobs JP, Burke RP, Quintessenza JA, Mavroudis C: Congenital Heart Surgery Nomenclature and Database Project: ventricular septal defect. Ann Thor Surg. 2000, 69 (Suppl 4): S25-S35. 10.1016\/S0003-4975(99)01270-9.","journal-title":"Ann Thor Surg"},{"key":"144_CR6","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1017\/S1047951113001686","volume":"23","author":"RH Anderson","year":"2013","unstructured":"Anderson RH, Spicer DE, Giroud JM, Mohun TJ: Tetralogy of fallot: nosological, morphological, and morphogenetic considerations. Cardiol Young. 2013, 23: 858-866. 10.1017\/S1047951113001686.","journal-title":"Cardiol Young"},{"key":"144_CR7","doi-asserted-by":"crossref","unstructured":"Bailliard F, Spicer DE, Mohun TJ, Henry GW, Anderson RH: The problems that exist when considering the anatomic variability between the channels that permit interventricular shunting. Cardiol Young 2014, doi:10.1017\/S1047951114000869,","DOI":"10.1017\/S1047951114000869"},{"key":"144_CR8","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/0167-5273(86)90114-2","volume":"13","author":"RH Anderson","year":"1986","unstructured":"Anderson RH, Becker AE, Tynan M: Description of ventricular septal defects - or how long is a piece of string?. Int J Cardiol. 1986, 13: 267-278. 10.1016\/0167-5273(86)90114-2.","journal-title":"Int J Cardiol"},{"key":"144_CR9","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1002\/ar.22949","volume":"297","author":"RH Anderson","year":"2014","unstructured":"Anderson RH, Spicer DE, Brown NA, Mohun TJ: The development of septation in the four-chambered heart. Anat Rec. 2014, 297: 1414-1429. 10.1002\/ar.22949.","journal-title":"Anat Rec"},{"key":"144_CR10","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S0022-5223(19)37981-4","volume":"79","author":"S Milo","year":"1980","unstructured":"Milo S, Ho SY, Wilkinson JL, Anderson RH: Surgical anatomy and atrioventricular conduction tissues of hearts with isolated ventricular septal defects. J Thorac Cardiovasc Surg. 1980, 79: 244-255.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"144_CR11","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/0002-9149(79)90178-4","volume":"44","author":"S Milo","year":"1979","unstructured":"Milo S, Ho SY, Macartney FJ, Wilkinson JL, Becker AE, Wenink ACG, Gittenberger-de Groot AC, Anderson RH: Straddling and overriding atrioventricular valves morphology and classification. Am J Cardiol. 1979, 44: 1122-1134. 10.1016\/0002-9149(79)90178-4.","journal-title":"Am J Cardiol"},{"key":"144_CR12","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.athoracsur.2012.08.040","volume":"95","author":"DE Spicer","year":"2013","unstructured":"Spicer DE, Anderson RH, Backer CL: Clarifying the surgical morphology of inlet ventricular septal defects. Ann Thor Surg. 2013, 95: 236-241. 10.1016\/j.athoracsur.2012.08.040.","journal-title":"Ann Thor Surg"},{"key":"144_CR13","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1378\/chest.58.5.468","volume":"58","author":"DA Goor","year":"1970","unstructured":"Goor DA, Lillehei CW, Rees R, Edwards JE: Isolated ventricular septal defect. Development basis for various types and presentation of classification. Chest. 1970, 58: 468-482. 10.1378\/chest.58.5.468.","journal-title":"Chest"},{"key":"144_CR14","volume-title":"Pediatric Cardiac Surgery","author":"WJ Wells","year":"1985","unstructured":"Wells WJ, Lindesmith GG: Ventricular Septal Defect. Pediatric Cardiac Surgery. Edited by: Arciniegas E. 1985, Year Book Medical Publishers, Chicago, Ill"},{"key":"144_CR15","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1016\/0735-1097(89)90431-2","volume":"14","author":"R Van Praagh","year":"1989","unstructured":"Van Praagh R, Geva T, Kreutzer J: Ventricular septal defects: how shall we describe, name and classify them?. J Am Coll Cardiol. 1989, 14: 1298-1299. 10.1016\/0735-1097(89)90431-2.","journal-title":"J Am Coll Cardiol"},{"key":"144_CR16","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1017\/S1047951100004583","volume":"8","author":"RH Anderson","year":"1998","unstructured":"Anderson RH, Ho SY, Falcao S, Daliento L, Rigby ML: The diagnostic features of atrioventricular septal defect with common atrioventricular junction. Cardiol Young. 1998, 8: 33-49. 10.1017\/S1047951100004583.","journal-title":"Cardiol Young"},{"key":"144_CR17","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s002469900502","volume":"20","author":"M Samanek","year":"1999","unstructured":"Samanek M, Voriskova M: Congenital heart disease among 815,569 children born between 1980 and 1990 and their 15-year survival: a prospective Bohemia survival study. Pediatr Cardiol. 1999, 20: 411-417. 10.1007\/s002469900502.","journal-title":"Pediatr Cardiol"},{"key":"144_CR18","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1017\/S1047951100003905","volume":"6","author":"DA Lewis","year":"1996","unstructured":"Lewis DA, Loffredo CA, Correa-Villasenor A, Wilson D, Martin GR: Descriptive epidemiology of membranous and muscular ventricular septal defects in the Baltimore-Washington Infant Study. Cardiol Young. 1996, 6: 281-290. 10.1017\/S1047951100003905.","journal-title":"Cardiol Young"},{"key":"144_CR19","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/0002-9149(65)90047-0","volume":"16","author":"JLE Hoffman","year":"1965","unstructured":"Hoffman JLE, Rudolph AM: The natural history of ventricular septal defects in infancy. Am J Cardiol. 1965, 16: 634-653. 10.1016\/0002-9149(65)90047-0.","journal-title":"Am J Cardiol"},{"key":"144_CR20","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1016\/0002-8703(68)90321-9","volume":"75","author":"R Van Praagh","year":"1968","unstructured":"Van Praagh R, McNamara JJ: Anatomic types of ventricular septal defect with aortic insufficiency. Diagnostic and surgical considerations. Am Heart J. 1968, 75: 604-619. 10.1016\/0002-8703(68)90321-9.","journal-title":"Am Heart J"},{"key":"144_CR21","doi-asserted-by":"crossref","unstructured":"Anderson RH, Spicer DE, Henry GW, Rigsby CL, Hlavacek AM, Mohun TJ: What is aortic overriding. Cardiol Young 2014, doi:10.1017\/S1047951114001139,","DOI":"10.1017\/S1047951114001139"},{"key":"144_CR22","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1097\/00000658-195809000-00012","volume":"148","author":"F Gerbode","year":"1958","unstructured":"Gerbode F, Hultgren H, Melrose D, Osborn J: Syndrome of left ventricular-right atrial shunt. Successful surgical repair of defect in five cases, with observation of bradycardia on closure. Ann Surg. 1958, 148: 433-446. 10.1097\/00000658-195809000-00012.","journal-title":"Ann Surg"},{"key":"144_CR23","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.athoracsur.2006.04.030","volume":"82","author":"HO Andersen","year":"2006","unstructured":"Andersen HO, de Leval MR, Tsang VT, Elliott MJ, Anderson RH, Cook AC: Is complete heart block after surgical closure of ventricular septum defects still an issue?. Ann Thorac Surg. 2006, 82: 948-957. 10.1016\/j.athoracsur.2006.04.030.","journal-title":"Ann Thorac Surg"},{"key":"144_CR24","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1016\/j.jacc.2003.10.047","volume":"43","author":"R Holzer","year":"2004","unstructured":"Holzer R, Balzer D, Cao QL, Lock K, Hijazi ZM: Device closure of muscular ventricular septal defects using the Amplatzer muscular ventricular septal defect occluder: immediate and mid-term results of a U.S. registry. JACC. 2004, 43: 1257-1263. 10.1016\/j.jacc.2003.10.047.","journal-title":"JACC"},{"key":"144_CR25","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1016\/j.jacc.2007.03.068","volume":"50","author":"G Butera","year":"2007","unstructured":"Butera G, Carminati M, Chessa M, Piazza L, Micheletti A, Negura DG, Abella R, Giamberti A, Frigiola A: Transcatheter closure of perimembranous ventricular septal defects: early and long-term results. JACC. 2007, 50: 1189-1195. 10.1016\/j.jacc.2007.03.068.","journal-title":"JACC"},{"key":"144_CR26","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1016\/j.jtcvs.2008.02.037","volume":"136","author":"D Predescu","year":"2008","unstructured":"Predescu D, Chaturvedi RR, Friedberg MK, Benson LN, Ozawa A, Lee KJ: Complete heart block associated with device closure of perimembranous ventricular septal defects. J Thorac Cardiovasc Surg. 2008, 136: 1223-1228. 10.1016\/j.jtcvs.2008.02.037.","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Orphanet Journal of Rare Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13023-014-0144-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13023-014-0144-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13023-014-0144-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13023-014-0144-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T07:11:53Z","timestamp":1630566713000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/s13023-014-0144-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["144"],"URL":"https:\/\/doi.org\/10.1186\/s13023-014-0144-2","relation":{},"ISSN":["1750-1172"],"issn-type":[{"value":"1750-1172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"24 April 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"144"}}