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Our aim was to review the existing evidence to identify overall diagnostic delay for IIM, factors associated with diagnostic delay, and people\u2019s experiences of diagnostic delay.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Three databases and grey literature sources were searched. Diagnostic delay was defined as the period between the onset of symptoms and the year of first diagnosis of IIM. We pooled the mean delay using random effects inverse variance meta-analysis and performed subgroup analyses.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>328 titles were identified from which 27 studies were included. Overall mean diagnostic delay was 27.91\u00a0months (95% CI 15.03\u201340.79, I<jats:sup>2<\/jats:sup>\u2009=\u200999%). Subgroup analyses revealed a difference in diagnostic delay between non-inclusion body myositis (IBM) and IBM types. There was no difference in diagnostic delay between studies in which myositis specific autoantibodies\u00a0(MSA) were tested or not tested. In countries with gatekeeper health systems, where primary care clinicians authorize access to specialty care, people experienced longer periods of diagnostic delay than people with IIM in countries with non-gatekeeper systems. While studies discussed factors that may influence diagnostic delay, significant associations were not identified. No qualitative studies examining people\u2019s experiences of diagnostic delay were identified.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Diagnostic delay of IIM has extensive impacts on the quality of life of people living with this disease. Understanding the experiences of people with IIM, from symptom onset to diagnosis, and factors that influence diagnostic delay is critical to inform clinical practice and training activities aimed at increasing awareness of this rare disease and expediting diagnosis.<\/jats:p>\n                <jats:p><jats:italic>Trial registration<\/jats:italic>: PROSPERO Registration number: CRD42022307236 <jats:italic>URL of the PROSPERO registration<\/jats:italic>: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.crd.york.ac.uk\/PROSPEROFILES\/307236_PROTOCOL_20220127.pdf\">https:\/\/www.crd.york.ac.uk\/PROSPEROFILES\/307236_PROTOCOL_20220127.pdf<\/jats:ext-link><\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13023-022-02570-9","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T05:02:40Z","timestamp":1669006960000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Diagnostic delay of myositis: an integrated systematic review"],"prefix":"10.1186","volume":"17","author":[{"given":"Tergel","family":"Namsrai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Parkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-4593","authenticated-orcid":false,"given":"Jane","family":"Desborough","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,21]]},"reference":[{"key":"2570_CR1","doi-asserted-by":"publisher","first-page":"64","DOI":"10.3389\/fneur.2016.00064","volume":"7","author":"A Malik","year":"2016","unstructured":"Malik A, et al. 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