{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:25:15Z","timestamp":1772166315507,"version":"3.50.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100010653","name":"Masarykova Univerzita","doi-asserted-by":"publisher","award":["This work was supported by the European Regional Development Fund - Project ENOCH (No. CZ.02.1.01\/0.0\/0.0\/16_019\/0000868). This publication was written at Masaryk University as part of the project entitled \"Novel imaging, computing and analytical methods in cardiovascular diseases diagnostics and monitoring\" number MUNI\/A\/1462\/2021 with the support of the Specific University Research Grant, as provided by the Ministry of Education, Youth and Sports of the Czech Republic in the year 2022."],"award-info":[{"award-number":["This work was supported by the European Regional Development Fund - Project ENOCH (No. CZ.02.1.01\/0.0\/0.0\/16_019\/0000868). This publication was written at Masaryk University as part of the project entitled \"Novel imaging, computing and analytical methods in cardiovascular diseases diagnostics and monitoring\" number MUNI\/A\/1462\/2021 with the support of the Specific University Research Grant, as provided by the Ministry of Education, Youth and Sports of the Czech Republic in the year 2022."]}],"id":[{"id":"10.13039\/501100010653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Orphanet J Rare Dis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Female carriers of dystrophin gene mutations (DMD-FC) were previously considered non-manifesting, but in recent decades, cardiomyopathy associated with muscular dystrophy and myocardial fibrosis has been described. Our study aimed to assess prospectively myocardial fibrosis in asymptomatic DMD-FC compared to a sex-matched control group (CG) with similar age distribution using native T\n                      <jats:sub>1<\/jats:sub>\n                      mapping and extracellular volume (ECV) quantification by cardiovascular magnetic resonance (CMR) imaging.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      38 DMD-FC with verified genetic mutation and 22 healthy volunteers were included. Using CMR, native T\n                      <jats:sub>1<\/jats:sub>\n                      relaxation time and ECV quantification were determined in each group. Late gadolinium enhancement (LGE) was assessed in all cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 38 DMD-FC (mean age 39.1\u2009\u00b1\u20098.8 years) and 22 healthy volunteers (mean age 39.9\u2009\u00b1\u200912.6 years) imagined by CMR. The mean global native T\n                      <jats:sub>1<\/jats:sub>\n                      relaxation time was similar for DMD-FC and CG (1005.1\u2009\u00b1\u200926.3 ms vs. 1003.5\u2009\u00b1\u200925.0 ms; p-value\u2009=\u20090.81). Likewise, the mean global ECV value was also similar between the groups (27.92\u2009\u00b1\u20092.02% vs. 27.10\u2009\u00b1\u20092.89%; p-value\u2009=\u20090.20). The segmental analysis of mean ECV values according to the American Heart Association classification did not show any differences between DMD-FC and CG. There was a non-significant trend towards higher mean ECV values of DMD-FC in the inferior and inferolateral segments of the myocardium (p-value\u2009=\u20090.075 and 0.070 respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      There were no statistically significant differences in the mean global and segmental native T\n                      <jats:sub>1<\/jats:sub>\n                      relaxation times and the mean global or segmental ECV values. There was a trend towards higher segmental mean ECV values of DMD-FC in the inferior and inferolateral walls of the myocardium.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13023-023-02899-9","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T09:02:28Z","timestamp":1694422948000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Myocardial native T1 mapping and extracellular volume quantification in asymptomatic female carriers of Duchenne muscular dystrophy gene mutations"],"prefix":"10.1186","volume":"18","author":[{"given":"Lucia","family":"Mas\u00e1rov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-132X","authenticated-orcid":false,"given":"Roman","family":"Panovsk\u00fd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Pe\u0161l","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Luz","family":"Mojica-Pisciotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1\u0161","family":"Hole\u010dek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladim\u00edr","family":"Kincl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lenka","family":"Ju\u0159\u00edkov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"M\u00e1chal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luk\u00e1\u0161","family":"Opat\u0159il","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u011bra","family":"Feitov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"issue":"21","key":"2899_CR1","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.1016\/j.jacc.2016.02.081","volume":"67","author":"F Kamdar","year":"2016","unstructured":"Kamdar F, Garry DJ. Dystrophin-Deficient Cardiomyopathy. J Am Coll Cardiol. 2016;67(21):2533\u201346.","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"2899_CR2","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.nmd.2010.04.008","volume":"20","author":"MCE Hermans","year":"2010","unstructured":"Hermans MCE, Pinto YM, Merkies ISJ, de Die-Smulders CEM, Crijns HJGM, Faber CG. Hereditary muscular dystrophies and the heart. Neuromuscul Disord NMD. 2010;20(8):479\u201392.","journal-title":"Neuromuscul Disord NMD"},{"issue":"13","key":"2899_CR3","doi-asserted-by":"publisher","first-page":"e200","DOI":"10.1161\/CIR.0000000000000526","volume":"136","author":"B Feingold","year":"2017","unstructured":"Feingold B, Mahle WT, Auerbach S, Clemens P, Domenighetti AA, Jefferies JL, et al. Management of Cardiac involvement Associated with Neuromuscular Diseases: A Scientific Statement from the American Heart Association. Circulation. 2017;136(13):e200\u201331.","journal-title":"Circulation"},{"issue":"18","key":"2899_CR4","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1161\/CIRCULATIONAHA.114.015151","volume":"131","author":"EM McNally","year":"2015","unstructured":"McNally EM, Kaltman JR, Benson DW, Canter CE, Cripe LH, Duan D, et al. Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with parent project muscular dystrophy. Circulation. 2015;131(18):1590\u20138.","journal-title":"Circulation"},{"key":"2899_CR5","first-page":"587","volume":"21","author":"J Demos","year":"1962","unstructured":"Demos J, Dreyfus JC, Schapira F, Schapira G. [Biological anomalies in the apparently healthy transmitters of muscular dystrophy]. Rev Can Biol. 1962;21:587\u201397.","journal-title":"Rev Can Biol"},{"issue":"2","key":"2899_CR6","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1007\/s00246-018-2046-x","volume":"40","author":"T Aikawa","year":"2019","unstructured":"Aikawa T, Takeda A, Oyama-Manabe N, Naya M, Yamazawa H, Koyanagawa K, et al. Progressive left ventricular dysfunction and myocardial fibrosis in Duchenne and Becker muscular dystrophy: a longitudinal cardiovascular magnetic resonance study. Pediatr Cardiol. 2019;40(2):384\u201392.","journal-title":"Pediatr Cardiol"},{"issue":"6","key":"2899_CR7","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1002\/mus.25445","volume":"55","author":"T Mccaffrey","year":"2017","unstructured":"Mccaffrey T, Guglieri M, Murphy AP, Bushby K, Johnson A, Bourke JP. Cardiac involvement in female carriers of duchenne or becker muscular dystrophy. Muscle Nerve. 2017;55(6):810\u20138.","journal-title":"Muscle Nerve"},{"issue":"7","key":"2899_CR8","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1007\/s00246-015-1192-7","volume":"36","author":"SM Lang","year":"2015","unstructured":"Lang SM, Shugh S, Mazur W, Sticka JJ, Rattan MS, Jefferies JL, et al. Myocardial fibrosis and left ventricular dysfunction in Duchenne muscular dystrophy carriers using Cardiac magnetic resonance imaging. Pediatr Cardiol. 2015;36(7):1495\u2013501.","journal-title":"Pediatr Cardiol"},{"key":"2899_CR9","doi-asserted-by":"publisher","unstructured":"Solheim TA, Fornander F, Raja AA, M\u00f8gelvang R, Poulsen NS, Dun\u00f8 M, et al. Cardiac involvement in women with pathogenic dystrophin gene variants. Front Neurol. 2021;12:707838. Available from: https:\/\/www.frontiersin.org\/articles\/.\u00a0https:\/\/doi.org\/10.3389\/fneur.2021.707838.","DOI":"10.3389\/fneur.2021.707838"},{"issue":"8","key":"2899_CR10","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.nmd.2010.05.010","volume":"20","author":"P Soltanzadeh","year":"2010","unstructured":"Soltanzadeh P, Friez MJ, Dunn D, von Niederhausern A, Gurvich OL, Swoboda KJ, et al. Clinical and genetic characterization of manifesting carriers of DMD mutations. Neuromuscul Disord NMD. 2010;20(8):499\u2013504.","journal-title":"Neuromuscul Disord NMD"},{"issue":"1","key":"2899_CR11","first-page":"61","volume":"18","author":"P Wexberg","year":"2016","unstructured":"Wexberg P, Avanzini M, Mascherbauer J, Pfaffenberger S, Freudenthaler B, Bittner R, et al. Myocardial late gadolinium enhancement is associated with clinical presentation in Duchenne muscular dystrophy carriers. J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson. 2016;18(1):61.","journal-title":"J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson"},{"issue":"3","key":"2899_CR12","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1093\/ehjci\/jev161","volume":"17","author":"A Florian","year":"2016","unstructured":"Florian A, R\u00f6sch S, Bietenbeck M, Engelen M, Stypmann J, Waltenberger J, et al. Cardiac involvement in female Duchenne and Becker muscular dystrophy carriers in comparison to their first-degree male relatives: a comparative cardiovascular magnetic resonance study. Eur Heart J Cardiovasc Imaging. 2016;17(3):326\u201333.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"8","key":"2899_CR13","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1016\/j.jacc.2010.11.013","volume":"57","author":"N Mewton","year":"2011","unstructured":"Mewton N, Liu CY, Croisille P, Bluemke D, Lima JAC. Assessment of myocardial fibrosis with cardiovascular magnetic resonance. J Am Coll Cardiol. 2011;57(8):891\u2013903.","journal-title":"J Am Coll Cardiol"},{"issue":"9","key":"2899_CR14","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1093\/ehjci\/jeu050","volume":"15","author":"A Florian","year":"2014","unstructured":"Florian A, Ludwig A, R\u00f6sch S, Yildiz H, Sechtem U, Yilmaz A. Myocardial fibrosis imaging based on T1-mapping and extracellular volume fraction (ECV) measurement in muscular dystrophy patients: diagnostic value compared with conventional late gadolinium enhancement (LGE) imaging. Eur Heart J Cardiovasc Imaging. 2014;15(9):1004\u201312.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"7","key":"2899_CR15","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1007\/s00246-017-1690-x","volume":"38","author":"JJ Starc","year":"2017","unstructured":"Starc JJ, Moore RA, Rattan MS, Villa CR, Gao Z, Mazur W, et al. Elevated myocardial extracellular volume fraction in Duchenne muscular dystrophy. Pediatr Cardiol. 2017;38(7):1485\u201392.","journal-title":"Pediatr Cardiol"},{"key":"2899_CR16","doi-asserted-by":"crossref","unstructured":"Soslow J, Damon S, Crum K, Lawson M, Slaughter J, Xu M et al. Increased myocardial native T1 and extracellular volume in patients with Duchenne muscular dystrophy. J Cardiovasc Magn Reson. 2015;18.","DOI":"10.1186\/s12968-016-0224-7"},{"issue":"1","key":"2899_CR17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s13023-021-01704-9","volume":"16","author":"R Panovsk\u00fd","year":"2021","unstructured":"Panovsk\u00fd R, Pe\u0161l M, M\u00e1chal J, Hole\u010dek T, Feitov\u00e1 V, Ju\u0159\u00edkov\u00e1 L, et al. Quantitative assessment of left ventricular longitudinal function and myocardial deformation in Duchenne muscular dystrophy patients. Orphanet J Rare Dis. 2021;16(1):57.","journal-title":"Orphanet J Rare Dis"},{"issue":"1","key":"2899_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12968-016-0224-7","volume":"18","author":"JH Soslow","year":"2016","unstructured":"Soslow JH, Damon SM, Crum K, Lawson MA, Slaughter JC, Xu M, et al. Increased myocardial native T1 and extracellular volume in patients with Duchenne muscular dystrophy. J Cardiovasc Magn Reson. 2016;18(1):5.","journal-title":"J Cardiovasc Magn Reson"},{"key":"2899_CR19","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.ijcard.2020.05.052","volume":"316","author":"ML Mah","year":"2020","unstructured":"Mah ML, Cripe L, Slawinski MK, Al-Zaidy SA, Camino E, Lehman KJ, et al. Duchenne and Becker muscular dystrophy carriers: evidence of cardiomyopathy by exercise and cardiac MRI testing. Int J Cardiol. 2020;316:257\u201365.","journal-title":"Int J Cardiol"},{"issue":"3","key":"2899_CR20","first-page":"320","volume":"20","author":"K Koyanagawa","year":"2021","unstructured":"Koyanagawa K, Kobayashi Y, Aikawa T, Takeda A, Shiraishi H, Tsuneta S, et al. Myocardial T(1)-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: early experience. Magn Reson Med Sci MRMS off J Jpn Soc Magn Reson Med. 2021;20(3):320\u20134.","journal-title":"Magn Reson Med Sci MRMS off J Jpn Soc Magn Reson Med"},{"issue":"1","key":"2899_CR21","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/RMR.0000000000000013","volume":"23","author":"M Jerosch-Herold","year":"2014","unstructured":"Jerosch-Herold M, Kwong RY. Cardiac T(1) imaging. Top Magn Reson Imaging TMRI. 2014;23(1):3\u201311.","journal-title":"Top Magn Reson Imaging TMRI"},{"issue":"1","key":"2899_CR22","first-page":"19","volume":"22","author":"J Schulz-Menger","year":"2020","unstructured":"Schulz-Menger J, Bluemke DA, Bremerich J, Flamm SD, Fogel MA, Friedrich MG, et al. Standardized image interpretation and post-processing in cardiovascular magnetic resonance \u2013 2020 update: Society for Cardiovascular magnetic resonance (SCMR): Board of Trustees Task Force on standardized post-processing. J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson. 2020;22(1):19.","journal-title":"J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson"},{"issue":"4","key":"2899_CR23","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1161\/hc0402.102975","volume":"105","author":"MD Cerqueira","year":"2002","unstructured":"Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105(4):539\u201342.","journal-title":"Circulation"},{"key":"2899_CR24","doi-asserted-by":"crossref","unstructured":"Mavrogeni S, Papavasiliou A, Giannakopoulou K, Markousis-Mavrogenis G, Pons MR, Karanasios E et al. Oedema-fibrosis in Duchenne muscular dystrophy: role of cardiovascular magnetic resonance imaging. Eur J Clin Invest. 2017;47(12).","DOI":"10.1111\/eci.12843"},{"issue":"1","key":"2899_CR25","first-page":"107","volume":"15","author":"KN Hor","year":"2013","unstructured":"Hor KN, Taylor MD, Al-Khalidi HR, Cripe LH, Raman SV, Jefferies JL, et al. Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function. J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson. 2013;15(1):107.","journal-title":"J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson"},{"issue":"2","key":"2899_CR26","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s00380-021-01910-2","volume":"37","author":"G van Woerden","year":"2022","unstructured":"van Woerden G, van Veldhuisen DJ, Gorter TM, Willems TP, van Empel VPM, Peters A, et al. The clinical and prognostic value of late Gadolinium enhancement imaging in heart failure with mid-range and preserved ejection fraction. Heart Vessels. 2022;37(2):273\u201381.","journal-title":"Heart Vessels"},{"key":"2899_CR27","doi-asserted-by":"crossref","unstructured":"Xu K, Xu H, Xu R, Xie L, jun, Yang Z gang, Yu L et al. Global, segmental and layer specific analysis of myocardial involvement in Duchenne muscular dystrophy by cardiovascular magnetic resonance native T1 mapping. J Cardiovasc Magn Reson. 2021;23(1):110.","DOI":"10.1186\/s12968-021-00802-8"},{"issue":"1","key":"2899_CR28","first-page":"85","volume":"22","author":"NG Maforo","year":"2020","unstructured":"Maforo NG, Magrath P, Moulin K, Shao J, Kim GH, Prosper A, et al. T(1)-Mapping and extracellular volume estimates in pediatric subjects with Duchenne muscular dystrophy and healthy controls at 3T. J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson. 2020;22(1):85.","journal-title":"J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson"},{"issue":"1","key":"2899_CR29","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s12968-016-0292-8","volume":"18","author":"LJ Olivieri","year":"2016","unstructured":"Olivieri LJ, Kellman P, McCarter RJ, Cross RR, Hansen MS, Spurney CF. Native T1 values identify myocardial changes and stratify disease severity in patients with Duchenne muscular dystrophy. J Cardiovasc Magn Reson. 2016;18(1):72.","journal-title":"J Cardiovasc Magn Reson"},{"issue":"4","key":"2899_CR30","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/S0046-8177(76)80053-6","volume":"7","author":"KA Frankel","year":"1976","unstructured":"Frankel KA, Rosser RJ. The pathology of the heart in progressive muscular dystrophy: epimyocardial fibrosis. Hum Pathol. 1976;7(4):375\u201386.","journal-title":"Hum Pathol"},{"issue":"8","key":"2899_CR31","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.crad.2016.02.013","volume":"71","author":"RJ Everett","year":"2016","unstructured":"Everett RJ, Stirrat CG, Semple SIR, Newby DE, Dweck MR, Mirsadraee S. Assessment of myocardial fibrosis with T1 mapping MRI. Clin Radiol. 2016;71(8):768\u201378.","journal-title":"Clin Radiol"},{"issue":"1","key":"2899_CR32","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1002\/mrm.20110","volume":"52","author":"DR Messroghli","year":"2004","unstructured":"Messroghli DR, Radjenovic A, Kozerke S, Higgins DM, Sivananthan MU, Ridgway JP. Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn Reson Med. 2004;52(1):141\u20136.","journal-title":"Magn Reson Med"},{"issue":"4","key":"2899_CR33","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.jcmg.2012.08.019","volume":"6","author":"VO Puntmann","year":"2013","unstructured":"Puntmann VO, Voigt T, Chen Z, Mayr M, Karim R, Rhode K, et al. Native T1 mapping in differentiation of normal myocardium from diffuse disease in hypertrophic and dilated cardiomyopathy. JACC Cardiovasc Imaging. 2013;6(4):475\u201384.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1","key":"2899_CR34","doi-asserted-by":"publisher","first-page":"20794","DOI":"10.1038\/s41598-020-77882-6","volume":"10","author":"V Kincl","year":"2020","unstructured":"Kincl V, Panovsk\u00fd R, Pe\u0161l M, M\u00e1chal J, Ju\u0159\u00edkov\u00e1 L, Haberlov\u00e1 J, et al. Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers. Sci Rep. 2020;10(1):20794.","journal-title":"Sci Rep"},{"issue":"5","key":"2899_CR35","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1016\/j.jcmg.2020.09.016","volume":"14","author":"L Mas\u00e1rov\u00e1","year":"2021","unstructured":"Mas\u00e1rov\u00e1 L, Mojica-Pisciotti ML, Panovsk\u00fd R, Kincl V, Pe\u0161l M, et al. Decreased global strains of LV in asymptomatic female duchenne muscular dystrophy gene carriers using CMR-FT. JACC Cardiovasc Imaging. 2021 May;14(5):1070\u20131072. https:\/\/doi.org\/10.1016\/j.jcmg.2020.09.016.","journal-title":"JACC Cardiovasc Imaging"},{"issue":"18","key":"2899_CR36","doi-asserted-by":"publisher","first-page":"1874","DOI":"10.1016\/j.jacc.2006.10.078","volume":"49","author":"MC Silva","year":"2007","unstructured":"Silva MC, Meira ZMA, Gurgel Giannetti J, da Silva MM, Campos AFO, de Barbosa M. Myocardial delayed enhancement by magnetic resonance imaging in patients with muscular dystrophy. J Am Coll Cardiol. 2007;49(18):1874\u20139.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"2899_CR37","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s10554-008-9352-y","volume":"25","author":"MD Puchalski","year":"2009","unstructured":"Puchalski MD, Williams RV, Askovich B, Sower CT, Hor KH, Su JT, et al. Late gadolinium enhancement: precursor to cardiomyopathy in Duchenne muscular dystrophy? Int J Cardiovasc Imaging. 2009;25(1):57\u201363.","journal-title":"Int J Cardiovasc Imaging"},{"issue":"1","key":"2899_CR38","first-page":"53","volume":"15","author":"F von Knobelsdorff-Brenkenhoff","year":"2013","unstructured":"von Knobelsdorff-Brenkenhoff F, Prothmann M, Dieringer MA, Wassmuth R, Greiser A, Schwenke C, et al. Myocardial T1 and T2 mapping at 3 T: reference values, influencing factors and implications. J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson. 2013;15(1):53.","journal-title":"J Cardiovasc Magn Reson off J Soc Cardiovasc Magn Reson"}],"updated-by":[{"DOI":"10.1186\/s13023-023-02922-z","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000}}],"container-title":["Orphanet Journal of Rare Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13023-023-02899-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13023-023-02899-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13023-023-02899-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T20:30:26Z","timestamp":1700253026000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/s13023-023-02899-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,11]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["2899"],"URL":"https:\/\/doi.org\/10.1186\/s13023-023-02899-9","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-2372788\/v1","asserted-by":"object"}]},"ISSN":["1750-1172"],"issn-type":[{"value":"1750-1172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,11]]},"assertion":[{"value":"19 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2023","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1186\/s13023-023-02922-z","URL":"https:\/\/doi.org\/10.1186\/s13023-023-02922-z","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was performed in accordance with the Declaration of Helsinki (2000) of the World Medical Association. Ethics Committee of the Faculty Hospital St. Anne\u2019s (reference number 55\u00a0V\/2016) approved the study. Written informed consent was obtained from the subjects and\/or their legally authorised representative.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"no person\u00b4s personal data are published.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"283"}}