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Both wild and domestic ruminants may be relevant in the epidemiology of\n                      <jats:italic>C. burnetii<\/jats:italic>\n                      infection. In order to investigate the significance of the ruminant host community in the alpine and subalpine ecosystems of the Eastern Pyrenees, Northeastern Spain, in the epidemiology of Q fever, a serological survey was performed on samples from 599 wild and 353 sympatric domestic ruminants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Specific antibodies against\n                      <jats:italic>C. burnetii<\/jats:italic>\n                      were detected with a commercial enzyme-linked immunosorbent assay (ELISA). Domestic sheep showed the highest prevalence (12.7\u00a0%, CI 95\u00a0% 8.6\u201316.9), followed by European mouflon (\n                      <jats:italic>Ovis orientalis musimon<\/jats:italic>\n                      ) with a 6.8\u00a0% prevalence (CI 95\u00a0% 1.6\u201312.1), red deer (\n                      <jats:italic>Cervus elaphus<\/jats:italic>\n                      ) with 2.4\u00a0% (CI 95\u00a0% 0\u20135.6), and cattle with a prevalence of 1.1\u00a0% (CI 95\u00a0% 0\u20133.2). No positive domestic goats, fallow deer (\n                      <jats:italic>Dama dama<\/jats:italic>\n                      ), roe deer (\n                      <jats:italic>Capreolus capreolus<\/jats:italic>\n                      ) and Southern chamois (\n                      <jats:italic>Rupicapra pyrenaica<\/jats:italic>\n                      ) were detected. Sheep flock prevalence was 75\u00a0% (nine of the 12 sheep flocks sampled were positive, within-flock prevalence ranging from 11.1 to 25.0\u00a0%), whereas cattle herd prevalence was 11.1\u00a0% (one out of the nine cattle herds sampled was positive, within-herd prevalence of 10.0\u00a0%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Both domestic and wild ruminants from the alpine and subalpine ecosystems of the Eastern Pyrenees were exposed to\n                      <jats:italic>C. burnetii<\/jats:italic>\n                      . The higher seroprevalence in sheep and its relative abundance suggest that this species may have a major contribution to the ecology of\n                      <jats:italic>C. burnetii<\/jats:italic>\n                      . Conversely, wild ruminants do not seem to represent a relevant host community for\n                      <jats:italic>C. burnetii<\/jats:italic>\n                      maintenance in the Eastern Pyrenees.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13028-016-0209-4","type":"journal-article","created":{"date-parts":[[2016,4,27]],"date-time":"2016-04-27T08:41:24Z","timestamp":1461746484000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Serological survey of Coxiella burnetii at the wildlife\u2013livestock interface in the Eastern Pyrenees, Spain"],"prefix":"10.1186","volume":"58","author":[{"given":"Xavier","family":"Fern\u00e1ndez-Aguilar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d3scar","family":"Cabez\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreu","family":"Colom-Cadena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Lav\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Ram\u00f3n","family":"L\u00f3pez-Olvera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,27]]},"reference":[{"key":"209_CR1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","volume":"12","author":"M Maurin","year":"1999","unstructured":"Maurin M, Raoult D. 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