{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T19:44:59Z","timestamp":1768074299608,"version":"3.49.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BioPsychoSocial Med"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Psychosocial stress can induce various physical symptoms, including fever, which is a commonly seen symptom in pediatric practice. In cases of unexplained fever, psychogenic fever should be considered as a potential cause. Children with neurodevelopmental disorders may be more vulnerable to stress and therefore more prone to developing somatic symptoms than their peers. This study aimed to elucidate the characteristics of children with psychogenic fever and comorbidity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This study included 21 patients with psychogenic fever who visited the Department of Pediatric Psychosomatic Medicine, Okayama University Hospital. Information on age, sex, disease onset, final estimated diagnosis, comorbidities, treatment course, and outcome was obtained from the patients\u2019 medical records.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of the 21 patients included, 7 were boys and 14 were girls, and their median age was 13.0 (range: 8.6\u201314.6) years. A total of 19 patients had no attendance at school, and all patients showed signs of maladjustment in school. The comorbidities included orthostatic dysregulation (<jats:italic>n<\/jats:italic>\u2009=\u20094) and migraine (<jats:italic>n<\/jats:italic>\u2009=\u20093). Neurodevelopmental disorders were observed in nine patients, eight of whom were diagnosed after the initial visit. The mean treatment duration was 37.2 months. The outcomes were complete remission (<jats:italic>n<\/jats:italic>\u2009=\u20099), improvement (<jats:italic>n<\/jats:italic>\u2009=\u20094), discontinuation (<jats:italic>n<\/jats:italic>\u2009=\u20091), and referral to another physician (<jats:italic>n<\/jats:italic>\u2009=\u20097).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Various comorbidities were observed in the patients of this study with psychogenic fever, including the coexistence of neurodevelopmental disorders, such as autistic spectrum disorder. Children with neurodevelopmental disorders are prone to psychological stress resulting from difficulties in social adjustment. It is crucial to understand the developmental characteristics and environmental adaptation of patients to facilitate accurate diagnosis and treatment.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13030-024-00322-8","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T08:36:38Z","timestamp":1734510998000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Psychogenic fever and neurodevelopmental disorders among Japanese children"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9414-1650","authenticated-orcid":false,"given":"Ayumi","family":"Okada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshie","family":"Shigeyasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikako","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chie","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mana","family":"Hanzawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Sugihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Horiuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Tsukahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"key":"322_CR1","first-page":"6","volume":"19","author":"KW Hariman","year":"2013","unstructured":"Hariman KW, Lam SC, Lam YW, Luk KH, Poon KK, Li AM. Fever as a predictor of doctor shopping in the paediatric population. Hong Kong Med J. 2013;19:6\u201312.","journal-title":"Hong Kong Med J"},{"key":"322_CR2","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1080\/23328940.2015.1056907","volume":"2","author":"T Oka","year":"2015","unstructured":"Oka T. Psychogenic fever how psychological stress affects body temperature in the clinical population. Temperature. 2015;2:368\u201378.","journal-title":"Temperature"},{"key":"322_CR3","first-page":"324","volume":"2","author":"B Olivier","year":"2015","unstructured":"Olivier B. Psychogenic fever, functional fever, or psychogenic hyperthermia? Temp (Austin). 2015;2:324\u20135.","journal-title":"Temp (Austin)"},{"key":"322_CR4","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/1751-0759-1-11","volume":"1","author":"T Oka","year":"2007","unstructured":"Oka T, Oka K. Age and gender differences of psychogenic fever: a review of the Japanese literature. 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J Abnorm Child Psychol. 2017;45:1247\u20137.","journal-title":"J Abnorm Child Psychol"}],"container-title":["BioPsychoSocial Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13030-024-00322-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13030-024-00322-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13030-024-00322-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T09:07:59Z","timestamp":1734512879000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpsmedicine.biomedcentral.com\/articles\/10.1186\/s13030-024-00322-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,18]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["322"],"URL":"https:\/\/doi.org\/10.1186\/s13030-024-00322-8","relation":{},"ISSN":["1751-0759"],"issn-type":[{"value":"1751-0759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,18]]},"assertion":[{"value":"8 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethics Committee of the Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Science and Okayama University Hospital (No. 2204-011).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed-->Competing interests"}}],"article-number":"23"}}