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Contact james.tribble@ki.se; Twitter @james_r_tribble.PAW is an Assistant Professor in Medical Sciences at the Karolinska Institutet researching neurodegenerative and neuroprotective mechanisms. Contact pete.williams@ki.se; Twitter @pete_the_teapot; .BC is an Emeritus Professor at Cardiff University researching degenerative joint diseases and connective tissue proteoglycans. FS is Head and Professor of Neurosience at Cardiff University studying development, plasticity and visual processing in the primary visual cortex. JEM is Professor of Ophthalmology at Cardiff University and Honorary Consultant Ophthalmologist at the University Hospital of Wales, UK. He also holds an appointment at the School of Optometry and Vision Sciences, Cardiff University. 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