{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:59:22Z","timestamp":1778914762361,"version":"3.51.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,7,12]],"date-time":"2014-07-12T00:00:00Z","timestamp":1405123200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Hematol Oncol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/s13045-014-0049-5","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T12:26:34Z","timestamp":1405081594000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["IMP3 signatures of fallopian tube: a risk for pelvic serous cancers"],"prefix":"10.1186","volume":"7","author":[{"given":"Yiying","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dake","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingmin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,7,12]]},"reference":[{"key":"49_CR1","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1056\/NEJM199311183292108","volume":"329","author":"SA Cannistra","year":"1993","unstructured":"Cannistra SA: Cancer of the ovary. N Engl J Med. 1993, 329: 1550-1559. 10.1056\/NEJM199311183292108.","journal-title":"N Engl J Med"},{"key":"49_CR2","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1756-8722-5-8","volume":"5","author":"J Li","year":"2012","unstructured":"Li J, Fadare O, Xiang L, Kong B, Zheng W: Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis. J Hematol Oncol. 2012, 5: 8-10.1186\/1756-8722-5-8.","journal-title":"J Hematol Oncol"},{"key":"49_CR3","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1111\/j.1365-2559.2011.04167.x","volume":"61","author":"D Delair","year":"2012","unstructured":"Delair D, Soslow RA: Key features of extrauterine pelvic serous tumours (fallopian tube, ovary, and peritoneum). Histopathology. 2012, 61: 329-339. 10.1111\/j.1365-2559.2011.04167.x.","journal-title":"Histopathology"},{"key":"49_CR4","first-page":"20","volume":"9","author":"MA Brewer","year":"2003","unstructured":"Brewer MA, Johnson K, Follen M, Gershenson D, Bast R: Prevention of ovarian cancer: intraepithelial neoplasia. Clin Cancer Res. 2003, 9: 20-30.","journal-title":"Clin Cancer Res"},{"key":"49_CR5","doi-asserted-by":"publisher","first-page":"5119","DOI":"10.1002\/cncr.25450","volume":"116","author":"CP Crum","year":"2010","unstructured":"Crum CP, Xian W: Bringing the p53 signature into focus. Cancer. 2010, 116: 5119-5121. 10.1002\/cncr.25450.","journal-title":"Cancer"},{"key":"49_CR6","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1002\/path.4263","volume":"231","author":"CP Crum","year":"2013","unstructured":"Crum CP, Herfs M, Ning G, Bijron JG, Howitt BE, Jimenez CA, Hanamornroongruang S, McKeon FD, Xian W: Through the glass darkly: intraepithelial neoplasia, top-down differentiation, and the road to ovarian cancer. J Pathol. 2013, 231: 402-412. 10.1002\/path.4263.","journal-title":"J Pathol"},{"key":"49_CR7","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1038\/modpathol.2011.106","volume":"24","author":"J Li","year":"2011","unstructured":"Li J, Abushahin N, Pang S, Xiang L, Chambers SK, Fadare O, Kong B, Zheng W: Tubal origin of \u2018ovarian\u2019 low-grade serous carcinoma. Mod Pathol. 2011, 24: 1488-1499. 10.1038\/modpathol.2011.106.","journal-title":"Mod Pathol"},{"key":"49_CR8","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1038\/modpathol.2011.175","volume":"25","author":"CM Quick","year":"2012","unstructured":"Quick CM, Ning G, Bijron J, Laury A, Wei TS, Chen EY, Vargas SO, Betensky RA, McKeon FD, Xian W, Crum CP: PAX2-null secretory cell outgrowths in the oviduct and their relationship to pelvic serous cancer. Mod Pathol. 2012, 25: 449-455. 10.1038\/modpathol.2011.175.","journal-title":"Mod Pathol"},{"key":"49_CR9","doi-asserted-by":"publisher","first-page":"4160","DOI":"10.1200\/JCO.2008.16.4814","volume":"26","author":"JW Carlson","year":"2008","unstructured":"Carlson JW, Miron A, Jarboe EA, Parast MM, Hirsch MS, Lee YH, Muto MG, Kindelberger D, Crum CP: Serous tubal intraepithelial carcinoma: its potential role in primary peritoneal serous carcinoma and serous cancer prevention. J Clin Oncol. 2008, 26: 4160-4165. 10.1200\/JCO.2008.16.4814.","journal-title":"J Clin Oncol"},{"key":"49_CR10","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/GCO.0b013e328011a21f","volume":"19","author":"CP Crum","year":"2007","unstructured":"Crum CP, Drapkin R, Miron A, Ince TA, Muto M, Kindelberger DW, Lee Y: The distal fallopian tube: a new model for pelvic serous carcinogenesis. Curr Opin Obstet Gynecol. 2007, 19: 3-9. 10.1097\/GCO.0b013e328011a21f.","journal-title":"Curr Opin Obstet Gynecol"},{"key":"49_CR11","first-page":"31","volume":"1","author":"C Chen","year":"2013","unstructured":"Chen C, Li J, Yao G, Chambers SK, Wenxin Z:Tubal origin of ovarian low-grade serous\u00a0carcinoma. Am J Clin Exp Obstet Gynecol. 2013, 1: 31-36.","journal-title":"Am J Clin Exp Obstet Gynecol"},{"key":"49_CR12","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.molonc.2009.01.004","volume":"3","author":"CP Crum","year":"2009","unstructured":"Crum CP: Intercepting pelvic cancer in the distal fallopian tube: theories and realities. Mol Oncol. 2009, 3: 165-170. 10.1016\/j.molonc.2009.01.004.","journal-title":"Mol Oncol"},{"key":"49_CR13","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1002\/path.2761","volume":"222","author":"EY Chen","year":"2010","unstructured":"Chen EY, Mehra K, Mehrad M, Ning G, Miron A, Mutter GL, Monte N, Quade BJ, McKeon FD, Yassin Y, Xian W, Crum CP: Secretory cell outgrowth, PAX2 and serous carcinogenesis in the Fallopian tube. J Pathol. 2010, 222: 110-116. 10.1002\/path.2761.","journal-title":"J Pathol"},{"key":"49_CR14","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1038\/onc.2009.402","volume":"29","author":"K Levanon","year":"2010","unstructured":"Levanon K, Ng V, Piao HY, Zhang Y, Chang MC, Roh MH, Kindelberger DW, Hirsch MS, Crum CP, Marto JA, Drapkin R: Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis. Oncogene. 2010, 29: 1103-1113. 10.1038\/onc.2009.402.","journal-title":"Oncogene"},{"key":"49_CR15","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.ygyno.2013.09.018","volume":"131","author":"J Li","year":"2013","unstructured":"Li J, Ning Y, Abushahin N, Yuan Z, Wang YY, Wang Y, Yuan BB, Cragun JM, Chambers SK, Hatch K, Kong BH, Zheng WX: Secretory cell expansion with aging: risk for pelvic serous carcinogenesis. Gynecol Oncol. 2013, 131: 555-560. 10.1016\/j.ygyno.2013.09.018.","journal-title":"Gynecol Oncol"},{"key":"49_CR16","doi-asserted-by":"publisher","first-page":"625","DOI":"10.2741\/e275","volume":"3","author":"K Mehra","year":"2011","unstructured":"Mehra K, Mehrad M, Ning G, Drapkin R, McKeon FD, Xian W, Crum CP: STICS, SCOUTs and p53 signatures; a new language for pelvic serous carcinogenesis. Front Biosci (Elite Ed). 2011, 3: 625-634. 10.2741\/e275.","journal-title":"Front Biosci (Elite Ed)"},{"issue":"Suppl 1","key":"49_CR17","doi-asserted-by":"publisher","first-page":"S29","DOI":"10.1097\/IGC.0b013e31824d7269","volume":"22","author":"CP Crum","year":"2012","unstructured":"Crum CP, McKeon FD, Xian W: BRCA, the oviduct, and the space and time continuum of pelvic serous carcinogenesis. Int J Gynecol Cancer. 2012, 22 (Suppl 1): S29-S34. 10.1097\/IGC.0b013e31824d7269.","journal-title":"Int J Gynecol Cancer"},{"key":"49_CR18","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/00004347-200304000-00001","volume":"22","author":"TJ Colgan","year":"2003","unstructured":"Colgan TJ: Challenges in the early diagnosis and staging of fallopian-tube carcinomas associated with BRCA mutations. Int J Gynecol Pathol. 2003, 22: 109-120. 10.1097\/00004347-200304000-00001.","journal-title":"Int J Gynecol Pathol"},{"key":"49_CR19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1002\/path.2091","volume":"211","author":"Y Lee","year":"2007","unstructured":"Lee Y, Miron A, Drapkin R, Nucci MR, Medeiros F, Saleemuddin A, Garder J, Birch C, Mou H, Gordon RW, Cramer DW, McKeon FD, Crum CP: A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol. 2007, 211: 26-35. 10.1002\/path.2091.","journal-title":"J Pathol"},{"key":"49_CR20","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1038\/modpathol.2009.89","volume":"22","author":"PA Shaw","year":"2009","unstructured":"Shaw PA, Rouzbahman M, Pizer ES, Pintilie M, Begley H: Candidate serous cancer precursors in fallopian tube epithelium of BRCA1\/2 mutation carriers. Mod Pathol. 2009, 22: 1133-1138. 10.1038\/modpathol.2009.89.","journal-title":"Mod Pathol"},{"key":"49_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/pgp.0b013e31814b191f","volume":"27","author":"E Jarboe","year":"2008","unstructured":"Jarboe E, Folkins A, Nucci MR, Kindelberger D, Drapkin R, Miron A, Lee Y, Crum CP: Serous carcinogenesis in the fallopian tube: a descriptive classification. Int J Gynecol Pathol. 2008, 27: 1-9. 10.1097\/pgp.0b013e31814b191f.","journal-title":"Int J Gynecol Pathol"},{"key":"49_CR22","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1038\/sj.onc.1201110","volume":"14","author":"F Mueller-Pillasch","year":"1997","unstructured":"Mueller-Pillasch F, Lacher U, Wallrapp C, Micha A, Zimmerhackl F, Hameister H, Varga G, Friess H, Buchler M, Beger HG, Vila MR, Adler G, Gress TM: Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein. Oncogene. 1997, 14: 2729-2733. 10.1038\/sj.onc.1201110.","journal-title":"Oncogene"},{"key":"49_CR23","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0925-4773(99)00160-4","volume":"88","author":"F Mueller-Pillasch","year":"1999","unstructured":"Mueller-Pillasch F, Pohl B, Wilda M, Lacher U, Beil M, Wallrapp C, Hameister H, Knochel W, Adler G, Gress TM: Expression of the highly conserved RNA binding protein KOC in embryogenesis. Mech Dev. 1999, 88: 95-99. 10.1016\/S0925-4773(99)00160-4.","journal-title":"Mech Dev"},{"key":"49_CR24","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/modpathol.2008.206","volume":"22","author":"M Kobel","year":"2009","unstructured":"Kobel M, Xu HD, Bourne PA, Spaulding BO, Shih IM, Mao TL, Soslow RA, Ewanowich CA, Kalloger SE, Mehl E, Lee CH, Huntsman D, Gilks CB: IGF2BP3 (IMP3) expression is a marker of unfavorable prognosis in ovarian carcinoma of clear cell subtype. Mod Pathol. 2009, 22: 469-475. 10.1038\/modpathol.2008.206.","journal-title":"Mod Pathol"},{"key":"49_CR25","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/S0378-1119(01)00866-6","volume":"287","author":"K Yaniv","year":"2002","unstructured":"Yaniv K, Yisraeli JK: The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis. Gene. 2002, 287: 49-54. 10.1016\/S0378-1119(01)00866-6.","journal-title":"Gene"},{"key":"49_CR26","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1097\/PAS.0b013e31823272d4","volume":"35","author":"D Lu","year":"2011","unstructured":"Lu D, Yang XF, Jiang NY, Woda BA, Liu Q, Dresser K, Mercurio AM, Rock KL, Jiang Z: IMP3, a new biomarker to predict progression of cervical intraepithelial neoplasia into invasive cancer. Am J Surg Pathol. 2011, 35: 1638-1645. 10.1097\/PAS.0b013e31823272d4.","journal-title":"Am J Surg Pathol"},{"key":"49_CR27","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1038\/modpathol.3800735","volume":"20","author":"CZ Li","year":"2007","unstructured":"Li CZ, Rock KL, Woda BA, Jiang Z, Fraire AE, Dresser K: IMP3 is a novel biomarker for adenocarcinoma in situ of the uterine cervix: an immunohistochemical study in comparison with p16(INK4a) expression. Mod Pathol. 2007, 20: 242-247. 10.1038\/modpathol.3800735.","journal-title":"Mod Pathol"},{"key":"49_CR28","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1097\/PAS.0b013e3181483ff8","volume":"32","author":"W Zheng","year":"2008","unstructured":"Zheng W, Yi X, Fadare O, Liang SX, Martel M, Schwartz PE, Jiang Z: The oncofetal protein IMP3: a novel biomarker for endometrial serous carcinoma. Am J Surg Pathol. 2008, 32: 304-315. 10.1097\/PAS.0b013e3181483ff8.","journal-title":"Am J Surg Pathol"},{"key":"49_CR29","doi-asserted-by":"publisher","first-page":"5579","DOI":"10.1158\/1078-0432.CCR-08-0504","volume":"14","author":"Z Jiang","year":"2008","unstructured":"Jiang Z, Chu PG, Woda BA, Liu Q, Balaji KC, Rock KL, Wu CL: Combination of quantitative IMP3 and tumor stage: a new system to predict metastasis for patients with localized renal cell carcinomas. Clin Cancer Res. 2008, 14: 5579-5584. 10.1158\/1078-0432.CCR-08-0504.","journal-title":"Clin Cancer Res"},{"key":"49_CR30","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1016\/S1470-2045(06)70732-X","volume":"7","author":"Z Jiang","year":"2006","unstructured":"Jiang Z, Chu PGG, Woda BA, Rock KL, Liu Q, Hsieh CC, Li CZ, Chen WG, Duan HO, McDougal S, Wu CL: Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study. Lancet Oncol. 2006, 7: 556-564. 10.1016\/S1470-2045(06)70732-X.","journal-title":"Lancet Oncol"},{"key":"49_CR31","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3109\/10520295.2011.591831","volume":"87","author":"JJ Findeis-Hosey","year":"2012","unstructured":"Findeis-Hosey JJ, Xu H: Insulin-like growth factor II-messenger RNA-binding protein-3 and lung cancer. Biotech Histochem. 2012, 87: 24-29. 10.3109\/10520295.2011.591831.","journal-title":"Biotech Histochem"},{"key":"49_CR32","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1097\/01.pas.0000180854.28831.77","volume":"30","author":"F Medeiros","year":"2006","unstructured":"Medeiros F, Muto MG, Lee Y, Elvin JA, Callahan MJ, Feltmate C, Garber JE, Cramer DW, Crum CP: The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol. 2006, 30: 230-236. 10.1097\/01.pas.0000180854.28831.77.","journal-title":"Am J Surg Pathol"},{"key":"49_CR33","doi-asserted-by":"publisher","first-page":"3985","DOI":"10.1200\/JCO.2007.12.2622","volume":"25","author":"MJ Callahan","year":"2007","unstructured":"Callahan MJ, Crum CP, Medeiros F, Kindelberger DW, Elvin JA, Garber JE, Feltmate CM, Berkowitz RS, Muto MG: Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction. J Clin Oncol. 2007, 25: 3985-3990. 10.1200\/JCO.2007.12.2622.","journal-title":"J Clin Oncol"},{"key":"49_CR34","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1097\/01.pas.0000149688.98333.54","volume":"29","author":"RK Yantiss","year":"2005","unstructured":"Yantiss RK, Woda BA, Fanger GR, Kalos M, Whalen GF, Tada H, Andersen DK, Rock KL, Dresser K: KOC (K homology domain containing protein overexpressed in cancer) - a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas. Am J Surg Pathol. 2005, 29: 188-195. 10.1097\/01.pas.0000149688.98333.54.","journal-title":"Am J Surg Pathol"},{"key":"49_CR35","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1158\/1055-9965.EPI-08-0771","volume":"18","author":"MT Goodman","year":"2009","unstructured":"Goodman MT, Shvetsov YB: Incidence of ovarian, peritoneal, and fallopian tube carcinomas in the United States, 1995\u20132004. Cancer Epidemiol Biomarkers Prev. 2009, 18: 132-139. 10.1158\/1055-9965.EPI-08-0771.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"49_CR36","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1097\/GRF.0b013e31824b1725","volume":"55","author":"CP Crum","year":"2012","unstructured":"Crum CP, McKeon FD, Xian W: The oviduct and ovarian cancer: causality, clinical implications, and \u201ctargeted prevention\u201d. Clin Obstet Gynecol. 2012, 55: 24-35. 10.1097\/GRF.0b013e31824b1725.","journal-title":"Clin Obstet Gynecol"},{"key":"49_CR37","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.ygyno.2009.01.013","volume":"113","author":"AK Folkins","year":"2009","unstructured":"Folkins AK, Jarboe EA, Roh MH, Crum CP: Precursors to pelvic serous carcinoma and their clinical implications. Gynecol Oncol. 2009, 113: 391-396. 10.1016\/j.ygyno.2009.01.013.","journal-title":"Gynecol Oncol"},{"key":"49_CR38","doi-asserted-by":"publisher","first-page":"5284","DOI":"10.1200\/JCO.2008.18.1107","volume":"26","author":"K Levanon","year":"2008","unstructured":"Levanon K, Crum C, Drapkin R: New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J Clin Oncol. 2008, 26: 5284-5293. 10.1200\/JCO.2008.18.1107.","journal-title":"J Clin Oncol"},{"key":"49_CR39","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/GRF.0b013e31824b4611","volume":"55","author":"J Hunn","year":"2012","unstructured":"Hunn J, Rodriguez GC: Ovarian cancer: etiology, risk factors, and epidemiology. Clin Obstet Gynecol. 2012, 55: 3-23. 10.1097\/GRF.0b013e31824b4611.","journal-title":"Clin Obstet Gynecol"},{"key":"49_CR40","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1038\/modpathol.2009.64","volume":"22","author":"DR Semmel","year":"2009","unstructured":"Semmel DR, Folkins AK, Hirsch MS, Nucci MR, Crum CP: Intercepting early pelvic serous carcinoma by routine pathological examination of the fimbria. Mod Pathol. 2009, 22: 985-988. 10.1038\/modpathol.2009.64.","journal-title":"Mod Pathol"},{"key":"49_CR41","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1111\/his.12046","volume":"62","author":"R Vang","year":"2013","unstructured":"Vang R, Shih Ie M, Kurman RJ: Fallopian tube precursors of ovarian low- and high-grade serous neoplasms. Histopathology. 2013, 62: 44-58. 10.1111\/his.12046.","journal-title":"Histopathology"},{"key":"49_CR42","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1097\/PGP.0b013e31822ea955","volume":"31","author":"S Tang","year":"2012","unstructured":"Tang S, Onuma K, Deb P, Wang E, Lytwyn A, Sur M, Daya D: Frequency of serous tubal intraepithelial carcinoma in various gynecologic malignancies: a study of 300 consecutive cases. Int J Gynecol Pathol. 2012, 31: 103-110. 10.1097\/PGP.0b013e31822ea955.","journal-title":"Int J Gynecol Pathol"},{"key":"49_CR43","first-page":"433","volume":"41","author":"J Wen","year":"2012","unstructured":"Wen J, Shi JL, Shen DH, Chen YX, Song QJ: Morphologic changes of fallopian tubal epithelium in ovarian serous tumors. Zhonghua Bing Li Xue Za Zhi. 2012, 41: 433-437.","journal-title":"Zhonghua Bing Li Xue Za Zhi"}],"container-title":["Journal of Hematology &amp; Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13045-014-0049-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13045-014-0049-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13045-014-0049-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13045-014-0049-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T04:32:29Z","timestamp":1630557149000},"score":1,"resource":{"primary":{"URL":"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-014-0049-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,12]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["49"],"URL":"https:\/\/doi.org\/10.1186\/s13045-014-0049-5","relation":{},"ISSN":["1756-8722"],"issn-type":[{"value":"1756-8722","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,12]]},"assertion":[{"value":"29 April 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2014","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2014","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"49"}}