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However, the reproducibility of measuring foot dimensions using 3D scans in children and adolescents with Down syndrome is unknown. The aim of this study was to determine the intra\u2010 and inter\u2010rater reproducibility of measuring foot dimensions of children and adolescents with Down syndrome using 3D scanning.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>3D foot scans of 30 participants with Down syndrome aged 5 to 17\u2009years were obtained using the FotoScan 3D scanner. Foot dimensions assessed were foot length, ball of foot length, outside ball of foot length, diagonal foot width, horizontal foot width, heel width, ball girth, instep girth, first and fifth toe height, and instep height. Additionally, the Wesjflog Index and forefoot shape were determined. Measurements were completed by two raters independently on two separate occasions, 2 weeks apart. Intra\u2010 and inter\u2010rater reliability were assessed using intra\u2010class coefficients (ICCs) and Gwet's AC1 statistics with 95% confidence intervals. Agreement was determined by calculating limits of agreement (LOA) and percentage agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighteen participants were female and 12 were male (mean age 10.6 [3.9] years). Intra\u2010rater reproducibility (ICCs ranged from 0.74 to 0.99, 95% LOA from \u2212\u200913.7\u2009mm to 16.3\u2009mm) and inter\u2010rater reproducibility (ICCs ranging from 0.73 to 0.99, 95% LOA from \u2212\u200918.8\u2009mm to 12.7\u2009mm) was good to excellent, although some measurements (ball of foot length, outside ball of foot length, heel width and girth measurements) displayed wider LOAs indicating relatively poorer agreement. Forefoot shape displayed substantial to almost perfect reliability (Gwet's AC1 0.68 to 0.85) and percentage agreement ranged from 73 to 87%, indicating acceptable agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The measurement of specific foot dimensions of children and adolescents with Down syndrome using 3D scans is reproducible. Findings of this study may be used to support future research measuring specific foot dimensions of children and adolescents with Down syndrome using 3D foot scans.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s13047-020-00403-1","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T10:02:56Z","timestamp":1591264976000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Reproducibility of foot dimensions measured from 3\u2010dimensional foot scans in children and adolescents with Down syndrome"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3472-8502","authenticated-orcid":false,"given":"Nirmeen M.","family":"Hassan","sequence":"first","affiliation":[{"name":"Discipline of Podiatry School of Allied Health Human Services and Sport La Trobe University 3086 Victoria Australia"},{"name":"Living with Disability Research Centre School of Allied Health 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Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl B.","family":"Landorf","sequence":"additional","affiliation":[{"name":"La Trobe Sport and Exercise Medicine Research Centre School of Allied Health Human Services and Sport 3086 Victoria Australia"},{"name":"Discipline of Podiatry School of Allied Health Human Services and Sport La Trobe University 3086 Victoria Australia"},{"name":"Living with Disability Research Centre School of Allied Health Human Services and Sport La Trobe University 3086 Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hylton B.","family":"Menz","sequence":"additional","affiliation":[{"name":"La Trobe Sport and Exercise Medicine Research Centre School of Allied Health Human Services and Sport 3086 Victoria Australia"},{"name":"Discipline of Podiatry School of Allied Health Human Services and Sport La Trobe University 3086 Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon E.","family":"Munteanu","sequence":"additional","affiliation":[{"name":"La Trobe Sport and Exercise Medicine Research Centre School of Allied Health Human Services and Sport 3086 Victoria Australia"},{"name":"Discipline of Podiatry School of Allied Health Human Services and Sport La Trobe University 3086 Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,4]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000033"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108749.2004.tb00483.x"},{"issue":"4","key":"e_1_2_15_4_1","first-page":"3","article-title":"Non congenital heart disease aspects of Down's syndrome","volume":"4","author":"Bianca S","year":"2002","journal-title":"Images Paediatr 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All authors have read and approved the final manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"31"}}