{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:39:54Z","timestamp":1775043594853,"version":"3.50.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation","doi-asserted-by":"crossref","award":["32200957"],"award-info":[{"award-number":["32200957"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation","doi-asserted-by":"crossref","award":["82003113"],"award-info":[{"award-number":["82003113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Sichuan Science and Technology Program","award":["2024NSFSC1889"],"award-info":[{"award-number":["2024NSFSC1889"]}]},{"name":"Sichuan Provincial People's Hospital Foundation","award":["25QMPY004"],"award-info":[{"award-number":["25QMPY004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ovarian Res"],"DOI":"10.1186\/s13048-026-02044-7","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T03:37:14Z","timestamp":1772077034000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["ARNTL deregulation promotes ovarian cancer progression and metastasis by activating cancer-associated fibroblasts"],"prefix":"10.1186","volume":"19","author":[{"given":"Yanna","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaoya","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanxi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanpei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"issue":"4","key":"2044_CR1","doi-asserted-by":"publisher","first-page":"47","DOI":"10.21037\/cco-20-34","volume":"9","author":"P Gaona-Luviano","year":"2020","unstructured":"Gaona-Luviano P, Medina-Gaona LA, Maga\u00f1a-P\u00e9rez K. Epidemiology of ovarian cancer. Chin Clin Oncol. 2020;9(4):47\u201347.","journal-title":"Chin Clin Oncol"},{"issue":"2","key":"2044_CR2","first-page":"93","volume":"22","author":"AT Ali","year":"2023","unstructured":"Ali AT, Al-Ani O, Al-Ani F. Epidemiology and risk factors for ovarian cancer. Menopause Review\/Przegl\u0105d Menopauzalny. 2023;22(2):93\u2013104.","journal-title":"Menopause Review\/Przegl\u0105d Menopauzalny"},{"key":"2044_CR3","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.bpobgyn.2020.02.010","volume":"65","author":"Z Nash","year":"2020","unstructured":"Nash Z, Menon U. Ovarian cancer screening: Current status and future directions. Best Pract Res Clin Obstet Gynecol. 2020;65:32\u201345.","journal-title":"Best Pract Res Clin Obstet Gynecol"},{"issue":"6586","key":"2044_CR4","doi-asserted-by":"publisher","first-page":"eaay9040","DOI":"10.1126\/science.aay9040","volume":"375","author":"D Crosby","year":"2022","unstructured":"Crosby D, et al. Early detection of cancer. Science. 2022;375(6586):eaay9040.","journal-title":"Science"},{"issue":"4","key":"2044_CR5","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/s41591-022-01746-x","volume":"28","author":"RC Fitzgerald","year":"2022","unstructured":"Fitzgerald RC, et al. The future of early cancer detection. Nat Med. 2022;28(4):666\u201377.","journal-title":"Nat Med"},{"issue":"4","key":"2044_CR6","doi-asserted-by":"publisher","first-page":"e32774","DOI":"10.1097\/MD.0000000000032774","volume":"102","author":"Y Liu","year":"2023","unstructured":"Liu Y, et al. Neoadjuvant chemotherapy in advanced epithelial ovarian cancer by histology: A SEER based survival analysis. Medicine. 2023;102(4):e32774.","journal-title":"Medicine"},{"issue":"4","key":"2044_CR7","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/j.gendis.2022.02.007","volume":"10","author":"U Anand","year":"2023","unstructured":"Anand U, et al. Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics. Genes Dis. 2023;10(4):1367\u2013401.","journal-title":"Genes Dis"},{"issue":"10","key":"2044_CR8","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1038\/s12276-021-00681-0","volume":"53","author":"Y Lee","year":"2021","unstructured":"Lee Y. Roles of circadian clocks in cancer pathogenesis and treatment. Exp Mol Med. 2021;53(10):1529\u201338.","journal-title":"Exp Mol Med"},{"issue":"1","key":"2044_CR9","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/s41392-022-00899-y","volume":"7","author":"F Fagiani","year":"2022","unstructured":"Fagiani F, et al. Molecular regulations of circadian rhythm and implications for physiology and diseases. Signal Transduct Target therapy. 2022;7(1):41.","journal-title":"Signal Transduct Target therapy"},{"issue":"1","key":"2044_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.20892\/j.issn.2095-3941.2022.0474","volume":"20","author":"C Huang","year":"2023","unstructured":"Huang C, et al. Major roles of the circadian clock in cancer. Cancer Biology Med. 2023;20(1):1.","journal-title":"Cancer Biology Med"},{"key":"2044_CR11","doi-asserted-by":"publisher","first-page":"745808","DOI":"10.3389\/fonc.2021.745808","volume":"11","author":"M Ye","year":"2021","unstructured":"Ye M, et al. Applications of multi-omics approaches for exploring the molecular mechanism of ovarian carcinogenesis. Front Oncol. 2021;11:745808.","journal-title":"Front Oncol"},{"issue":"1","key":"2044_CR12","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41540-022-00225-w","volume":"8","author":"D Malhan","year":"2022","unstructured":"Malhan D, Basti A, Rel\u00f3gio A. Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes. npj Syst Biology Appl. 2022;8(1):17.","journal-title":"npj Syst Biology Appl"},{"key":"2044_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12943-020-01194-6","volume":"19","author":"H Shi","year":"2020","unstructured":"Shi H, et al. Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation. Mol Cancer. 2020;19:1\u201317.","journal-title":"Mol Cancer"},{"issue":"3","key":"2044_CR14","doi-asserted-by":"publisher","first-page":"e13915","DOI":"10.1111\/apha.13915","volume":"237","author":"LVM de Assis","year":"2023","unstructured":"de Assis LVM, Demir M, Oster H. The role of the circadian clock in the development, progression, and treatment of non-alcoholic fatty liver disease. Acta Physiol. 2023;237(3):e13915.","journal-title":"Acta Physiol"},{"issue":"2","key":"2044_CR15","doi-asserted-by":"publisher","first-page":"C306","DOI":"10.1152\/ajpcell.00166.2022","volume":"323","author":"Z Taleb","year":"2022","unstructured":"Taleb Z, Karpowicz P. Circadian regulation of digestive and metabolic tissues. Am J Physiology-Cell Physiol. 2022;323(2):C306\u201321.","journal-title":"Am J Physiology-Cell Physiol"},{"issue":"1","key":"2044_CR16","doi-asserted-by":"publisher","first-page":"e1007156","DOI":"10.1371\/journal.pgen.1007156","volume":"14","author":"AJ Trott","year":"2018","unstructured":"Trott AJ, Menet JS. Regulation of circadian clock transcriptional output by CLOCK: BMAL1. PLoS Genet. 2018;14(1):e1007156.","journal-title":"PLoS Genet"},{"issue":"22","key":"2044_CR17","doi-asserted-by":"publisher","first-page":"4409","DOI":"10.1111\/j.1432-1033.2004.04379.x","volume":"271","author":"F Sato","year":"2004","unstructured":"Sato F, et al. Functional analysis of the basic helix-loop\u2010helix transcription factor DEC1 in circadian regulation: Interaction with BMAL1. Eur J Biochem. 2004;271(22):4409\u201319.","journal-title":"Eur J Biochem"},{"issue":"1","key":"2044_CR18","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/s41392-020-00376-4","volume":"6","author":"Y Cao","year":"2021","unstructured":"Cao Y, et al. Targeting the signaling in Epstein\u2013Barr virus-associated diseases: mechanism, regulation, and clinical study. Signal Transduct Target therapy. 2021;6(1):15.","journal-title":"Signal Transduct Target therapy"},{"issue":"10","key":"2044_CR19","doi-asserted-by":"publisher","first-page":"3914","DOI":"10.1111\/cas.15928","volume":"114","author":"K Chen","year":"2023","unstructured":"Chen K, et al. ARNTL inhibits the malignant behaviors of oral cancer by regulating autophagy in an AKT\/mTOR pathway-dependent manner. Cancer Sci. 2023;114(10):3914\u201323.","journal-title":"Cancer Sci"},{"issue":"1","key":"2044_CR20","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1186\/s13046-023-02791-1","volume":"42","author":"D Zhao","year":"2023","unstructured":"Zhao D, et al. Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p\/PTEN signaling. J Experimental Clin Cancer Res. 2023;42(1):229.","journal-title":"J Experimental Clin Cancer Res"},{"issue":"1","key":"2044_CR21","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/s41419-025-07776-w","volume":"16","author":"L Ye","year":"2025","unstructured":"Ye L, et al. ARNTL-mediated INO80-DHX15 axis reprograms the glycolytic metabolism and augments the progression of endometrial carcinoma. Cell Death Dis. 2025;16(1):463.","journal-title":"Cell Death Dis"},{"issue":"7","key":"2044_CR22","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/s41419-024-06860-x","volume":"15","author":"W Zou","year":"2024","unstructured":"Zou W, et al. The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway. Cell Death Dis. 2024;15(7):466.","journal-title":"Cell Death Dis"},{"issue":"3","key":"2044_CR23","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/s00432-011-1126-6","volume":"138","author":"G Mazzoccoli","year":"2012","unstructured":"Mazzoccoli G, et al. ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer. J Cancer Res Clin Oncol. 2012;138(3):501\u201311.","journal-title":"J Cancer Res Clin Oncol"},{"issue":"1","key":"2044_CR24","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/s42003-024-05826-1","volume":"7","author":"C Chai","year":"2024","unstructured":"Chai C, et al. Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer. Commun Biology. 2024;7(1):131.","journal-title":"Commun Biology"},{"issue":"1","key":"2044_CR25","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1038\/s42003-025-08380-6","volume":"8","author":"D Zhang","year":"2025","unstructured":"Zhang D, et al. CAF-derived GLUT1 and its role in modulating ovarian cancer progression: a multi-dimensional analysis of the tumor microenvironment. Commun Biology. 2025;8(1):1020.","journal-title":"Commun Biology"},{"issue":"1","key":"2044_CR26","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1038\/s41698-025-00941-6","volume":"9","author":"M De Luise","year":"2025","unstructured":"De Luise M, et al. Perfusion-based ex vivo culture of frozen ovarian cancer tissues with preserved tumor microenvironment. npj Precision Oncol. 2025;9(1):152.","journal-title":"npj Precision Oncol"},{"issue":"4","key":"2044_CR27","doi-asserted-by":"publisher","first-page":"2218","DOI":"10.3390\/ijms23042218","volume":"23","author":"MJ Kim","year":"2022","unstructured":"Kim MJ, et al. GLIS1 in cancer-associated fibroblasts regulates the migration and invasion of ovarian cancer cells. Int J Mol Sci. 2022;23(4):2218.","journal-title":"Int J Mol Sci"},{"issue":"11","key":"2044_CR28","doi-asserted-by":"publisher","first-page":"406","DOI":"10.3390\/cancers10110406","volume":"10","author":"S Dasari","year":"2018","unstructured":"Dasari S, Fang Y, Mitra AK. Cancer associated fibroblasts: naughty neighbors that drive ovarian cancer progression. Cancers. 2018;10(11):406.","journal-title":"Cancers"},{"issue":"1","key":"2044_CR29","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3390\/biomedicines11010112","volume":"11","author":"R Sulaiman","year":"2023","unstructured":"Sulaiman R, et al. Patient-derived primary cancer-associated fibroblasts mediate resistance to anti-angiogenic drug in ovarian cancers. Biomedicines. 2023;11(1):112.","journal-title":"Biomedicines"},{"issue":"6","key":"2044_CR30","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1158\/1078-0432.CCR-22-1031","volume":"29","author":"KB Kennel","year":"2023","unstructured":"Kennel KB, et al. Cancer-associated fibroblasts in inflammation and antitumor immunity. Clin Cancer Res. 2023;29(6):1009\u201316.","journal-title":"Clin Cancer Res"},{"issue":"18","key":"2044_CR31","doi-asserted-by":"publisher","first-page":"3378","DOI":"10.1158\/0008-5472.CAN-24-3037","volume":"85","author":"JM Flynn","year":"2025","unstructured":"Flynn JM, et al. Plasticity and Functional Heterogeneity of Cancer-Associated Fibroblasts. Cancer Res. 2025;85(18):3378\u201398.","journal-title":"Cancer Res"},{"issue":"6","key":"2044_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3892\/ijo.2022.5357","volume":"60","author":"L Liang","year":"2022","unstructured":"Liang L, et al. Reverse Warburg effect\u2019of cancer\u2013associated fibroblasts. Int J Oncol. 2022;60(6):1\u201313.","journal-title":"Int J Oncol"},{"issue":"1","key":"2044_CR33","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s44337-024-00131-6","volume":"1","author":"ES Saheed","year":"2024","unstructured":"Saheed ES, et al. Mechanism of the Warburg effect and its role in breast cancer immunotherapy. Discover Med. 2024;1(1):110.","journal-title":"Discover Med"},{"issue":"1","key":"2044_CR34","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/cac2.12392","volume":"43","author":"Z Fang","year":"2023","unstructured":"Fang Z, et al. Signaling pathways in cancer-associated fibroblasts: recent advances and future perspectives. Cancer Commun. 2023;43(1):3\u201341.","journal-title":"Cancer Commun"},{"issue":"8","key":"2044_CR35","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1016\/j.cell.2023.03.016","volume":"186","author":"Y Chhabra","year":"2023","unstructured":"Chhabra Y, Weeraratna AT. Fibroblasts in cancer: Unity in heterogeneity. Cell. 2023;186(8):1580\u2013609.","journal-title":"Cell"},{"issue":"5","key":"2044_CR36","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1158\/1055-9965.EPI-18-1112","volume":"28","author":"L Leung","year":"2019","unstructured":"Leung L, et al. Shift work patterns, chronotype, and epithelial ovarian cancer risk. Cancer Epidemiol Biomarkers Prev. 2019;28(5):987\u201395.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"42","key":"2044_CR37","doi-asserted-by":"publisher","first-page":"eaaz4530","DOI":"10.1126\/sciadv.aaz4530","volume":"6","author":"I Aiello","year":"2020","unstructured":"Aiello I, et al. Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation. Sci Adv. 2020;6(42):eaaz4530.","journal-title":"Sci Adv"},{"issue":"2","key":"2044_CR38","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1101\/gr.222430.117","volume":"28","author":"J Yeung","year":"2018","unstructured":"Yeung J, et al. Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs. Genome Res. 2018;28(2):182\u201391.","journal-title":"Genome Res"},{"issue":"2","key":"2044_CR39","doi-asserted-by":"publisher","first-page":"017","DOI":"10.23937\/2378-3648\/1410017","volume":"2","author":"HS Jim","year":"2015","unstructured":"Jim HS, et al. Common genetic variation in circadian rhythm genes and risk of epithelial ovarian cancer (EOC). J Genet genome Res. 2015;2(2):017.","journal-title":"J Genet genome Res"},{"issue":"4","key":"2044_CR40","first-page":"670","volume":"168","author":"AW Lambert","year":"2017","unstructured":"Lambert AW, Pattabiraman DR, Weinberg RA. Emerging Biol principles metastasis Cell. 2017;168(4):670\u201391.","journal-title":"Emerging Biol principles metastasis Cell"},{"issue":"1","key":"2044_CR41","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1038\/s41392-025-02148-4","volume":"10","author":"Y Li","year":"2025","unstructured":"Li Y, et al. Invasion and metastasis in cancer: molecular insights and therapeutic targets. Signal Transduct Target therapy. 2025;10(1):57.","journal-title":"Signal Transduct Target therapy"},{"issue":"6","key":"2044_CR42","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1038\/s41571-018-0007-1","volume":"15","author":"KC Valkenburg","year":"2018","unstructured":"Valkenburg KC, De Groot AE, Pienta KJ. Targeting the tumour stroma to improve cancer therapy. Nat reviews Clin Oncol. 2018;15(6):366\u201381.","journal-title":"Nat reviews Clin Oncol"},{"issue":"4","key":"2044_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12032-025-02675-8","volume":"42","author":"Y Xiao","year":"2025","unstructured":"Xiao Y, et al. Contribution of tumor microenvironment (TME) to tumor apoptosis, angiogenesis, metastasis, and drug resistance. Med Oncol. 2025;42(4):1\u201314.","journal-title":"Med Oncol"},{"issue":"18","key":"2044_CR44","doi-asserted-by":"publisher","first-page":"4720","DOI":"10.3390\/cancers13184720","volume":"13","author":"PJ Asif","year":"2021","unstructured":"Asif PJ, et al. The role of cancer-associated fibroblasts in cancer invasion and metastasis. Cancers. 2021;13(18):4720.","journal-title":"Cancers"},{"issue":"1","key":"2044_CR45","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1152\/physrev.00048.2019","volume":"101","author":"G Biffi","year":"2020","unstructured":"Biffi G, Tuveson DA. Diversity and biology of cancer-associated fibroblasts. Physiol Rev. 2020;101(1):147\u201376.","journal-title":"Physiol Rev"},{"issue":"1","key":"2044_CR46","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/s13045-025-01688-0","volume":"18","author":"H Jia","year":"2025","unstructured":"Jia H, et al. Cancer associated fibroblasts in cancer development and therapy. J Hematol Oncol. 2025;18(1):36.","journal-title":"J Hematol Oncol"},{"issue":"18","key":"2044_CR47","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1038\/s41388-025-03408-x","volume":"44","author":"W Chen","year":"2025","unstructured":"Chen W, Wang Y-J. Multifaceted roles of OCT4 in tumor microenvironment: biology and therapeutic implications. Oncogene. 2025;44(18):1213\u201329.","journal-title":"Oncogene"},{"issue":"4","key":"2044_CR48","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1038\/s41568-023-00660-9","volume":"24","author":"S Yuan","year":"2024","unstructured":"Yuan S, Almagro J, Fuchs E. Beyond genetics: driving cancer with the tumour microenvironment behind the wheel. Nat Rev Cancer. 2024;24(4):274\u201386.","journal-title":"Nat Rev Cancer"},{"issue":"7","key":"2044_CR49","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1038\/s12276-023-01013-0","volume":"55","author":"D Yang","year":"2023","unstructured":"Yang D, et al. Cancer-associated fibroblasts: from basic science to anticancer therapy. Exp Mol Med. 2023;55(7):1322\u201332.","journal-title":"Exp Mol Med"},{"issue":"6","key":"2044_CR50","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1016\/j.ccell.2022.04.011","volume":"40","author":"H Huang","year":"2022","unstructured":"Huang H, et al. Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer. Cancer Cell. 2022;40(6):656\u201373. e7.","journal-title":"Cancer Cell"},{"issue":"3","key":"2044_CR51","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1111\/cas.16443","volume":"116","author":"M Yamazaki","year":"2025","unstructured":"Yamazaki M, Ishimoto T. Targeting Cancer-Associated Fibroblasts: Eliminate or Reprogram? Cancer Sci. 2025;116(3):613\u201321.","journal-title":"Cancer Sci"},{"issue":"1","key":"2044_CR52","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/s41420-025-02566-x","volume":"11","author":"H Masuda","year":"2025","unstructured":"Masuda H. Cancer-associated fibroblasts in cancer drug resistance and cancer progression: a review. Cell Death Discovery. 2025;11(1):341.","journal-title":"Cell Death Discovery"},{"issue":"1","key":"2044_CR53","doi-asserted-by":"publisher","first-page":"4294","DOI":"10.1038\/s41467-023-39762-1","volume":"14","author":"L Cords","year":"2023","unstructured":"Cords L, et al. Cancer-associated fibroblast classification in single-cell and spatial proteomics data. Nat Commun. 2023;14(1):4294.","journal-title":"Nat Commun"}],"container-title":["Journal of Ovarian Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13048-026-02044-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13048-026-02044-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13048-026-02044-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T10:04:15Z","timestamp":1775037855000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13048-026-02044-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":53,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2044"],"URL":"https:\/\/doi.org\/10.1186\/s13048-026-02044-7","relation":{},"ISSN":["1757-2215"],"issn-type":[{"value":"1757-2215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]},"assertion":[{"value":"18 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The research involving animals has been approved by the Animal Ethics Committee of West China Hospital of Sichuan University. All procedures followed the AVMA Guidelines for the Euthanasia of Animals (2020) and were approved by the Institutional Animal Care and Use Committee (protocol No. IACUC20220301146).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"130"}}