{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:46:19Z","timestamp":1776923179453,"version":"3.51.2"},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":38,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["QY25141"],"award-info":[{"award-number":["QY25141"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Clinical Key Incubation Project A of Peking University Third Hospital","award":["BYSYZD2023022"],"award-info":[{"award-number":["BYSYZD2023022"]}]},{"name":"Peking University Third Hospital Junior Eagle Program","award":["BYSYCY2025008"],"award-info":[{"award-number":["BYSYCY2025008"]}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"crossref","award":["2022M720295"],"award-info":[{"award-number":["2022M720295"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine","award":["ZYYCXTD-C-202404"],"award-info":[{"award-number":["ZYYCXTD-C-202404"]}]},{"name":"Key Projects of Yunnan Province Science and Technology Department","award":["202302AA310044"],"award-info":[{"award-number":["202302AA310044"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ovarian Res"],"DOI":"10.1186\/s13048-026-02073-2","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T17:35:10Z","timestamp":1773682510000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of maternal chronic viral hepatitis infections on pregnancy and neonatal outcomes in in vitro fertilization: a systematic review and meta-analysis"],"prefix":"10.1186","volume":"19","author":[{"given":"Di","family":"Mao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Nan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingmei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fen-Ting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jizhou","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xunsi","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Lun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"2073_CR1","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/S2468-1253(23)00197-8","volume":"8","author":"Global prevalence","year":"2023","unstructured":"Global prevalence. cascade of care, and prophylaxis coverage of hepatitis B in 2022: a modelling study. Lancet Gastroenterol Hepatol. 2023;8:879\u2013907.","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"2073_CR2","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1016\/j.cmi.2023.03.002","volume":"29","author":"S Wu","year":"2023","unstructured":"Wu S, Wang J, Guo Q, Lan H, Sun Y, Ren M, Liu Y, Wang P, Wang L, Su R, et al. Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: a systematic review and meta-analysis. Clin Microbiol Infect. 2023;29:1000\u20137.","journal-title":"Clin Microbiol Infect"},{"key":"2073_CR3","doi-asserted-by":"publisher","first-page":"102255","DOI":"10.1016\/j.tmaid.2022.102255","volume":"46","author":"N Salari","year":"2022","unstructured":"Salari N, Kazeminia M, Hemati N, Ammari-Allahyari M, Mohammadi M, Shohaimi S. Global prevalence of hepatitis C in general population: A systematic review and meta-analysis. Travel Med Infect Dis. 2022;46:102255.","journal-title":"Travel Med Infect Dis"},{"key":"2073_CR4","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1007\/s11427-024-2722-2","volume":"68","author":"J Xiao","year":"2025","unstructured":"Xiao J, Wang F, Yuan Y, Gao J, Xiao L, Yan C, Guo F, Zhong J, Che Z, Li W, et al. Epidemiology of liver diseases: global disease burden and forecasted research trends. Sci China Life Sci. 2025;68:541\u201357.","journal-title":"Sci China Life Sci"},{"key":"2073_CR5","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1016\/j.jhep.2022.05.016","volume":"77","author":"T Kushner","year":"2022","unstructured":"Kushner T, Djerboua M, Biondi MJ, Feld JJ, Terrault N, Flemming JA. Influence of hepatitis C viral parameters on pregnancy complications and risk of mother-to-child transmission. J Hepatol. 2022;77:1256\u201364.","journal-title":"J Hepatol"},{"key":"2073_CR6","doi-asserted-by":"publisher","first-page":"4677","DOI":"10.3748\/wjg.v18.i34.4677","volume":"18","author":"G Borgia","year":"2012","unstructured":"Borgia G, Carleo MA, Gaeta GB, Gentile I. Hepatitis B in pregnancy. World J Gastroenterol. 2012;18:4677\u201383.","journal-title":"World J Gastroenterol"},{"key":"2073_CR7","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1093\/humrep\/deae292","volume":"40","author":"Y Liang","year":"2025","unstructured":"Liang Y, Huang J, Zhao Q, Mo H, Su Z, Feng S, Li S, Ruan X. Global, regional, and national prevalence and trends of infertility among individuals of reproductive age (15\u201349 years) from 1990 to 2021, with projections to 2040. Hum Reprod. 2025;40:529\u201344.","journal-title":"Hum Reprod"},{"key":"2073_CR8","doi-asserted-by":"publisher","first-page":"5718","DOI":"10.3748\/wjg.v11.i36.5718","volume":"11","author":"F Ye","year":"2005","unstructured":"Ye F, Yue YF, Li SH, Chen TY, Zhang SL, Bai GQ, Liu M. Expression of HBsAg and HBcAg in the ovaries and ova of patients with chronic hepatitis B. World J Gastroenterol. 2005;11:5718\u201320.","journal-title":"World J Gastroenterol"},{"key":"2073_CR9","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.ajog.2005.07.011","volume":"194","author":"F Ye","year":"2006","unstructured":"Ye F, Yue Y, Li S, Chen T, Bai G, Liu M, Zhang S. Presence of HBsAg, HBcAg, and HBVDNA in ovary and ovum of the patients with chronic hepatitis B virus infection. Am J Obstet Gynecol. 2006;194:387\u201392.","journal-title":"Am J Obstet Gynecol"},{"key":"2073_CR10","doi-asserted-by":"publisher","first-page":"5565","DOI":"10.3748\/wjg.v11.i35.5565","volume":"11","author":"LZ Chen","year":"2005","unstructured":"Chen LZ, Fan XG, Gao JM. Detection of HBsAg, HBcAg, and HBV DNA in ovarian tissues from patients with HBV infection. World J Gastroenterol. 2005;11:5565\u20137.","journal-title":"World J Gastroenterol"},{"key":"2073_CR11","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.bpobgyn.2020.02.013","volume":"68","author":"JSM Mak","year":"2020","unstructured":"Mak JSM, Lao TT. Assisted reproduction in hepatitis carrier couples. Best Pract Res Clin Obstet Gynaecol. 2020;68:103\u20138.","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"2073_CR12","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1093\/humrep\/deg431","volume":"18","author":"A Devaux","year":"2003","unstructured":"Devaux A, Soula V, Sifer C, Branger M, Naouri M, Porcher R, Poncelet C, Neuraz A, Alvarez S, Benifla JL, et al. Hepatitis C virus detection in follicular fluid and culture media from HCV+ women, and viral risk during IVF procedures. Hum Reprod. 2003;18:2342\u20139.","journal-title":"Hum Reprod"},{"key":"2073_CR13","doi-asserted-by":"crossref","unstructured":"Liu L, Liang H, Yang J, Shen F, Li W. Analyzing the detrimental effects of female chronic hepatitis B virus DNA on ovarian reserve function and results of in vitro fertilization. Clin Exp Obstet Gynecol. 2022;49(1):4.","DOI":"10.31083\/j.ceog4901004"},{"key":"2073_CR14","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1093\/humrep\/deq317","volume":"26","author":"NF Hanafi","year":"2011","unstructured":"Hanafi NF, Abo Ali AH. Abo el kheir HF: ICSI outcome in women who have positive PCR result for hepatitis C virus. Hum Reprod. 2011;26:143\u20137.","journal-title":"Hum Reprod"},{"key":"2073_CR15","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1111\/jvh.13565","volume":"28","author":"M Farsimadan","year":"2021","unstructured":"Farsimadan M, Riahi SM, Muhammad HM, Emamvirdizadeh A, Tabasi M, Motamedifar M, Roviello G. The effects of hepatitis B virus infection on natural and IVF pregnancy: A meta-analysis study. J Viral Hepat. 2021;28:1234\u201345.","journal-title":"J Viral Hepat"},{"key":"2073_CR16","doi-asserted-by":"publisher","first-page":"e70002","DOI":"10.1002\/rmv.70002","volume":"34","author":"Y Guo","year":"2024","unstructured":"Guo Y, Zhou G, Feng Y, Zhang J, Liu Y, Yang X, Liu P, Feng Y, Xia X. The Association Between Male Viral Infections and Infertility: A Systematic Review and Meta-Analysis. Rev Med Virol. 2024;34:e70002.","journal-title":"Rev Med Virol"},{"key":"2073_CR17","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.","journal-title":"BMJ"},{"key":"2073_CR18","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.2307\/2533446","volume":"50","author":"CB Begg","year":"1994","unstructured":"Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088\u2013101.","journal-title":"Biometrics"},{"key":"2073_CR19","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629\u201334.","journal-title":"BMJ"},{"key":"2073_CR20","volume-title":"The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-Analyses","author":"GATP Wells","year":"2011","unstructured":"Wells GATP, O\u2019Connell D, Welch V, Peterson J, Shea B, Losos M. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomized Studies in Meta-Analyses. Ottawa: Ottawa Hospital Research Institute; 2011."},{"key":"2073_CR21","doi-asserted-by":"publisher","first-page":"e1230","DOI":"10.1002\/cl2.1230","volume":"18","author":"NR Haddaway","year":"2022","unstructured":"Haddaway NR, Page MJ, Pritchard CC, McGuinness LA. PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Syst Reviews. 2022;18:e1230.","journal-title":"Campbell Syst Reviews"},{"key":"2073_CR22","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.ejogrb.2013.10.002","volume":"172","author":"F Ye","year":"2014","unstructured":"Ye F, Liu Y, Jin Y, Shi J, Yang X, Liu X, Zhang X, Lin S, Kong Y, Zhang L. The effect of hepatitis B virus infected embryos on pregnancy outcome. Eur J Obstet Gynecol Reprod Biol. 2014;172:10\u20134.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2073_CR23","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1002\/jmv.23908","volume":"86","author":"L Shi","year":"2014","unstructured":"Shi L, Liu S, Zhao W, Zhou H, Ren W, Shi J. Hepatitis B virus infection reduces fertilization ability during in vitro fertilization and embryo transfer. J Med Virol. 2014;86:1099\u2013104.","journal-title":"J Med Virol"},{"key":"2073_CR24","first-page":"6230","volume":"8","author":"L Yang","year":"2015","unstructured":"Yang L, Zhao R, Zheng Y, Song X. Effect of hepatitis C virus infection on the outcomes of in vitro fertilization. Int J Clin Exp Med. 2015;8:6230\u20135.","journal-title":"Int J Clin Exp Med"},{"key":"2073_CR25","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.fertnstert.2019.03.039","volume":"112","author":"L Wang","year":"2019","unstructured":"Wang L, Li L, Huang C, Diao L, Lian R, Li Y, Xiao S, Hu X, Mo M, Zeng Y. Maternal chronic hepatitis B virus infection does not affect pregnancy outcomes in infertile patients receiving first in vitro fertilization treatment. Fertil Steril. 2019;112:250\u2013e257251.","journal-title":"Fertil Steril"},{"key":"2073_CR26","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1111\/jvh.13472","volume":"28","author":"Y Xiong","year":"2021","unstructured":"Xiong Y, Liu C, Huang S, Wang J, Qi Y, Yao G, Sun W, Qian Y, Ye L, Liu H, et al. Impact of maternal infection with hepatitis B virus on pregnancy complications and neonatal outcomes for women undergoing assisted reproductive technology treatment: A population-based study. J Viral Hepatitis. 2021;28:613\u201320.","journal-title":"J Viral Hepatitis"},{"key":"2073_CR27","doi-asserted-by":"crossref","unstructured":"Petric P, Fevzer T, Jancar N, Vrtacnik-Bokal E, Stimpfel M. Hepatitis B Infection Negatively Affects the Outcome of Fresh IVF\/ICSI Cycles. J Men\u2019s Health. 2022;18:1\u20137.","DOI":"10.31083\/j.jomh1807154"},{"key":"2073_CR28","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1111\/liv.15349","volume":"42","author":"W Yi","year":"2022","unstructured":"Yi W, Li M, Sun F, Lu H, Zeng Z, Bi X, Yang L, Lin Y, Cao X, Hu Y, et al. Impact of in vitro fertilization-embryo transfer on mother-to-infant transmission in women with chronic HBV infection. Liver Int. 2022;42:2167\u201374.","journal-title":"Liver Int"},{"key":"2073_CR29","doi-asserted-by":"publisher","first-page":"e2323495","DOI":"10.1001\/jamanetworkopen.2023.23495","volume":"6","author":"LL Ruan","year":"2023","unstructured":"Ruan LL, Chen MX, Adu-Gyamfi EA, Geng LH, Fu LJ, Wan Q, Ding YB. Maternal Hepatitis B Virus Infection and Pregnancy Outcomes of Freeze-Thaw Embryo Transfer. JAMA Netw Open. 2023;6:e2323495.","journal-title":"JAMA Netw Open"},{"key":"2073_CR30","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1111\/jvh.13878","volume":"30","author":"NZ Ma","year":"2023","unstructured":"Ma NZ, Dai W, Bao X, Bu ZQ, Shi H, Sun YP. Effects of hepatitis B virus infection on the treatment outcomes following in vitro fertilization\/intracytoplasmic sperm injection: An analysis of 21,999 first embryo transfer cycles. J Viral Hepat. 2023;30:889\u201396.","journal-title":"J Viral Hepat"},{"key":"2073_CR31","doi-asserted-by":"publisher","first-page":"hoaf015","DOI":"10.1093\/hropen\/hoaf015","volume":"2025","author":"F Liu","year":"2025","unstructured":"Liu F, Wang Z, Song Y, Tian T, Li R, Qiao J, Huang S, Wang Y. The impact of HBV, HCV, or syphilis infections on embryo and pregnancy outcomes in couples undergoing IVF treatment: a matched cohort study. Hum Reprod Open. 2025;2025:hoaf015.","journal-title":"Hum Reprod Open"},{"key":"2073_CR32","doi-asserted-by":"crossref","unstructured":"Xue KW, Wen LJ, Ji XL, Yan XY, Wen JQ, Li YZ, Zhang L. Impact of HBV Infection in Couples on In Vitro Fertilisation-Embryo Transfer Outcomes and Clinical Characteristics of Newborns: A Retrospective Study Based on 3900 Infertile Couples. J Viral Hepatitis. 2025;32(4):e70015.","DOI":"10.1111\/jvh.70015"},{"key":"2073_CR33","first-page":"6206","volume":"8","author":"S Lin","year":"2015","unstructured":"Lin S, Li R, Zheng X, Wang L, Ren X, Chen L, Liu Q, Liu P, Qiao J. Impact of hepatitis B virus carrier serostatus on neonatal outcomes after IVF-ET. Int J Clin Exp Med. 2015;8:6206\u201311.","journal-title":"Int J Clin Exp Med"},{"key":"2073_CR34","doi-asserted-by":"publisher","first-page":"e70015","DOI":"10.1111\/jvh.70015","volume":"32","author":"K Xue","year":"2025","unstructured":"Xue K, Wen L, Ji X, Yan X, Wen J, Li Y, Zhang L. Impact of HBV Infection in Couples on In Vitro Fertilisation-Embryo Transfer Outcomes and Clinical Characteristics of Newborns: A Retrospective Study Based on 3900 Infertile Couples. J Viral Hepat. 2025;32:e70015.","journal-title":"J Viral Hepat"},{"key":"2073_CR35","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/aji.12537","volume":"76","author":"L Qian","year":"2016","unstructured":"Qian L, Li Q, Li H. Effect of hepatitis B virus infection on sperm quality and oxidative stress state of the semen of infertile males. Am J Reprod Immunol. 2016;76:183\u20135.","journal-title":"Am J Reprod Immunol"},{"key":"2073_CR36","doi-asserted-by":"publisher","first-page":"e33471","DOI":"10.1371\/journal.pone.0033471","volume":"7","author":"X Kang","year":"2012","unstructured":"Kang X, Xie Q, Zhou X, Li F, Huang J, Liu D, Huang T. Effects of hepatitis B virus S protein exposure on sperm membrane integrity and functions. PLoS ONE. 2012;7:e33471.","journal-title":"PLoS ONE"},{"key":"2073_CR37","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1186\/s12884-025-08543-7","volume":"25","author":"J Cong","year":"2025","unstructured":"Cong J, Guo Y, Yi W. Retrospective analysis of adverse pregnancy outcomes associated with hepatitis B virus infection. BMC Pregnancy Childbirth. 2025;25:1343.","journal-title":"BMC Pregnancy Childbirth"},{"key":"2073_CR38","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.1002\/hep4.2002","volume":"6","author":"B Chen","year":"2022","unstructured":"Chen B, Wang Y, Lange M, Kushner T. Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7-year national inpatient sample study. Hepatol Commun. 2022;6:2465\u201373.","journal-title":"Hepatol Commun"},{"key":"2073_CR39","doi-asserted-by":"publisher","first-page":"e21416","DOI":"10.1097\/MD.0000000000021416","volume":"99","author":"R Jiang","year":"2020","unstructured":"Jiang R, Wang T, Yao Y, Zhou F, Huang X. Hepatitis B infection and intrahepatic cholestasis of pregnancy: A systematic review and meta-analysis. Med (Baltim). 2020;99:e21416.","journal-title":"Med (Baltim)"},{"key":"2073_CR40","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.ijgo.2012.12.020","volume":"121","author":"SM Rasheed","year":"2013","unstructured":"Rasheed SM, Abdel Monem AM, Abd Ellah AH, Abdel Fattah MS. Prognosis and determinants of pregnancy outcome among patients with post-hepatitis liver cirrhosis. Int J Gynaecol Obstet. 2013;121:247\u201351.","journal-title":"Int J Gynaecol Obstet"},{"key":"2073_CR41","doi-asserted-by":"publisher","first-page":"1166530","DOI":"10.3389\/fmed.2023.1166530","volume":"10","author":"M Weng","year":"2023","unstructured":"Weng M, Wang J, Yin J, Ren W, Wei C, Yang W, He H. Effects of HBsAg carriers on pregnancy complications in pregnant women: a retrospective cohort study. Front Med (Lausanne). 2023;10:1166530.","journal-title":"Front Med (Lausanne)"},{"key":"2073_CR42","doi-asserted-by":"crossref","unstructured":"EASL. 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol. 2017;67:370\u2013398.","DOI":"10.1016\/j.jhep.2017.03.021"},{"key":"2073_CR43","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1186\/s12884-021-03978-0","volume":"21","author":"S Zheng","year":"2021","unstructured":"Zheng S, Zhang H, Chen R, Yan J, Han Q. Pregnancy complicated with hepatitis B virus infection and preterm birth: a retrospective cohort study. BMC Pregnancy Childbirth. 2021;21:513.","journal-title":"BMC Pregnancy Childbirth"},{"key":"2073_CR44","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1016\/j.fertnstert.2015.12.008","volume":"105","author":"L Jin","year":"2016","unstructured":"Jin L, Nie R, Li Y, Xiao N, Zhu L, Zhu G. Hepatitis B surface antigen in oocytes and embryos may not result in vertical transmission to offspring of hepatitis B virus carriers. Fertil Steril. 2016;105:1010\u20133.","journal-title":"Fertil Steril"},{"key":"2073_CR45","first-page":"458","volume":"42","author":"SZ Masoumi","year":"2013","unstructured":"Masoumi SZ, Poorolajal J, Keramat A, Moosavi SA. Prevalence of Depression among Infertile Couples in Iran: A Meta-Analysis Study. Iran J Public Health. 2013;42:458\u201366.","journal-title":"Iran J Public Health"},{"key":"2073_CR46","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/j.rbmo.2022.01.015","volume":"44","author":"J Boivin","year":"2022","unstructured":"Boivin J, Vassena R, Costa M, Vegni E, Dixon M, Collura B, Markert M, Samuelsen C, Guiglotto J, Roitmann E, Domar A. Tailored support may reduce mental and relational impact of infertility on infertile patients and partners. Reprod Biomed Online. 2022;44:1045\u201354.","journal-title":"Reprod Biomed Online"},{"key":"2073_CR47","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s12879-019-3749-1","volume":"19","author":"S Peng","year":"2019","unstructured":"Peng S, Wan Z, Lin X, Li X, Du Y. Maternal hepatitis B surface antigen carrier status increased the incidence of gestational diabetes mellitus. BMC Infect Dis. 2019;19:147.","journal-title":"BMC Infect Dis"},{"key":"2073_CR48","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12985-021-01691-0","volume":"18","author":"W Yin","year":"2021","unstructured":"Yin W, Chen B, Yang Y, Li X, Li R, Xie J, Chen G, He F, Chen D. Association between maternal hepatitis B virus carrier and gestational diabetes mellitus: a retrospective cohort analysis. Virol J. 2021;18:226.","journal-title":"Virol J"},{"key":"2073_CR49","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1631\/jzus.B2300261","volume":"25","author":"L Zhang","year":"2024","unstructured":"Zhang L, Zhang F, Ma Z, Jin J. Hepatitis B virus infection, infertility, and assisted reproduction. J Zhejiang Univ Sci B. 2024;25:672\u201385.","journal-title":"J Zhejiang Univ Sci B"},{"key":"2073_CR50","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1097\/AOG.0000000000002423","volume":"131","author":"S Keyhan","year":"2018","unstructured":"Keyhan S, Truong T, Li YJ, Jackson-Bey T, Eaton JL. Preterm Delivery and Low Birth Weight Among Neonates Conceived With Intracytoplasmic Sperm Injection Compared With Conventional In Vitro Fertilization. Obstet Gynecol. 2018;131:262\u20138.","journal-title":"Obstet Gynecol"},{"key":"2073_CR51","doi-asserted-by":"crossref","unstructured":"Zhang C, Wei H, Zhao Z, Zhu Y. Adverse Pregnancy Outcomes and Prognostic Factors in Hepatitis B Virus Patients with Intrahepatic Cholestasis During Pregnancy. Clin Exp Obstet Gynecol. 2024;51(2):36.","DOI":"10.31083\/j.ceog5102036"},{"key":"2073_CR52","doi-asserted-by":"publisher","first-page":"7200","DOI":"10.1128\/JVI.02371-06","volume":"81","author":"P Bhat","year":"2007","unstructured":"Bhat P, Anderson DA. Hepatitis B virus translocates across a trophoblastic barrier. J Virol. 2007;81:7200\u20137.","journal-title":"J Virol"},{"key":"2073_CR53","first-page":"3235","volume":"8","author":"H Cui","year":"2016","unstructured":"Cui H, Chen J, Na Q. Effect of hepatitis B virus infection on trophoblast cell line (HTR-8\/SVneo) and choriocarcinoma cell line (JEG3) is linked to CD133-2 (AC141) expression. Am J Transl Res. 2016;8:3235\u201340.","journal-title":"Am J Transl Res"},{"key":"2073_CR54","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.3892\/etm.2021.10645","volume":"22","author":"Y Lin","year":"2021","unstructured":"Lin Y, Liu Y, Xu D, Guo F, Zhang W, Zhang Y, Bai G. HBxAg promotes HBV replication and EGFR activation in human placental trophoblasts. Exp Ther Med. 2021;22:1211.","journal-title":"Exp Ther Med"},{"key":"2073_CR55","doi-asserted-by":"crossref","unstructured":"Sirilert S, Tongsong T. Hepatitis B Virus Infection in Pregnancy: Immunological Response, Natural Course and Pregnancy Outcomes. J Clin Med. 2021;10(13):2926.","DOI":"10.3390\/jcm10132926"},{"key":"2073_CR56","doi-asserted-by":"crossref","unstructured":"Lawless L, Qin Y, Xie L, Zhang K. Trophoblast Differentiation: Mechanisms and Implications for Pregnancy Complications. Nutrients. 2023;15(16):3564.","DOI":"10.3390\/nu15163564"},{"key":"2073_CR57","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1111\/jvh.13585","volume":"28","author":"C Xu","year":"2021","unstructured":"Xu C, Bao Y, Zuo J, Li Y, Tang Y, Qu X, Ying H. Maternal chronic hepatitis B virus infection and the risk of preterm birth: A retrospective cohort analysis in Chinese women. J Viral Hepat. 2021;28:1422\u201330.","journal-title":"J Viral Hepat"},{"key":"2073_CR58","doi-asserted-by":"publisher","first-page":"e13083","DOI":"10.1111\/aji.13083","volume":"81","author":"L Li","year":"2019","unstructured":"Li L, Wang L, Huang C, Diao L, Zhang Y, Zhang X, Xu J, Zeng Y. Chronic hepatitis B infection alters peripheral immune response in women with reproductive failure. Am J Reprod Immunol. 2019;81:e13083.","journal-title":"Am J Reprod Immunol"},{"key":"2073_CR59","doi-asserted-by":"publisher","first-page":"66","DOI":"10.21037\/hbsn-2024-754","volume":"14","author":"R Yan","year":"2025","unstructured":"Yan R, Sun M, Yang H, Du S, Sun L, Mao Y. 2024 latest report on hepatitis B virus epidemiology in China: current status, changing trajectory, and challenges. Hepatobiliary Surg Nutr. 2025;14:66\u201377.","journal-title":"Hepatobiliary Surg Nutr"},{"key":"2073_CR60","doi-asserted-by":"publisher","first-page":"5427","DOI":"10.3748\/wjg.v20.i18.5427","volume":"20","author":"M Sunbul","year":"2014","unstructured":"Sunbul M. Hepatitis B virus genotypes: global distribution and clinical importance. World J Gastroenterol. 2014;20:5427\u201334.","journal-title":"World J Gastroenterol"},{"key":"2073_CR61","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.ijid.2022.06.017","volume":"122","author":"T Yue","year":"2022","unstructured":"Yue T, Zhang Q, Cai T, Xu M, Zhu H, Pourkarim MR, De Clercq E, Li G. Trends in the disease burden of HBV and HCV infection in China from 1990\u20132019. Int J Infect Dis. 2022;122:476\u201385.","journal-title":"Int J Infect Dis"},{"key":"2073_CR62","doi-asserted-by":"publisher","first-page":"2354","DOI":"10.1136\/gutjnl-2023-330691","volume":"72","author":"Z Liu","year":"2023","unstructured":"Liu Z, Lin C, Mao X, Guo C, Suo C, Zhu D, Jiang W, Li Y, Fan J, Song C, et al. Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people. Gut. 2023;72:2354\u201363.","journal-title":"Gut"}],"container-title":["Journal of Ovarian Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13048-026-02073-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13048-026-02073-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13048-026-02073-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:02:59Z","timestamp":1776920579000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13048-026-02073-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,16]]},"references-count":62,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2073"],"URL":"https:\/\/doi.org\/10.1186\/s13048-026-02073-2","relation":{},"ISSN":["1757-2215"],"issn-type":[{"value":"1757-2215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,16]]},"assertion":[{"value":"5 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"158"}}