{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T05:01:50Z","timestamp":1776747710567,"version":"3.51.2"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T00:00:00Z","timestamp":1562889600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T00:00:00Z","timestamp":1562889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ital J Pediatr"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s13052-019-0671-5","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T12:02:51Z","timestamp":1562932971000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Symptomatic malignant spinal cord compression in children: a single-center experience"],"prefix":"10.1186","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6232-5255","authenticated-orcid":false,"given":"Lucia","family":"De Martino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piero","family":"Spennato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Vetrella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Porfito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serena","family":"Ruotolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo Eraldo","family":"Abate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Cinalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Quaglietta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,7,12]]},"reference":[{"issue":"1","key":"671_CR1","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.pmr.2016.08.007","volume":"28","author":"LM Ruppert","year":"2017","unstructured":"Ruppert LM. Malignant spinal cord compression: adapting conventional rehabilitation approaches. Phys Med Rehabil Clin N Am. 2017;28(1):101\u201314.","journal-title":"Phys Med Rehabil Clin N Am"},{"issue":"2","key":"671_CR2","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1038\/sc.2009.130","volume":"48","author":"ML Costacurta","year":"2010","unstructured":"Costacurta ML, et al. Epidemiological profile of a pediatric population with acquired spinal cord injury from AACD: S\u00e3o Paulo\/Brazil. Spinal Cord. 2010;48(2):118\u201321.","journal-title":"Spinal Cord"},{"issue":"14","key":"671_CR3","doi-asserted-by":"publisher","first-page":"E878","DOI":"10.1097\/BRS.0b013e318294e839","volume":"38","author":"J Galvin","year":"2013","unstructured":"Galvin J, Scheinberg A, New PW. A retrospective case series of pediatric spinal cord injury and disease in Victoria, Australia. Spine (Phila Pa 1976). 2013;38(14):E878\u201382.","journal-title":"Spine (Phila Pa 1976)"},{"issue":"6","key":"671_CR4","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.ejpn.2013.05.014","volume":"17","author":"AN Sharpe","year":"2013","unstructured":"Sharpe AN, Forsyth R. Acute paediatric paraplegia: a case series review. Eur J Paediatr Neurol. 2013;17(6):620\u20134.","journal-title":"Eur J Paediatr Neurol"},{"issue":"3","key":"671_CR5","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1310\/sci16-00029","volume":"23","author":"E Smith","year":"2017","unstructured":"Smith E, Finn S, Fitzpatrick P. Epidemiology of pediatric traumatic and acquired nontraumatic spinal cord injury in Ireland. Top Spinal Cord Inj Rehabil. 2017;23(3):279\u201384.","journal-title":"Top Spinal Cord Inj Rehabil"},{"issue":"1","key":"671_CR6","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1200\/JCO.2001.19.1.183","volume":"19","author":"B De Bernardi","year":"2001","unstructured":"De Bernardi B, et al. Neuroblastoma with symptomatic spinal cord compression at diagnosis: treatment and results with 76 cases. J Clin Oncol. 2001;19(1):183\u201390.","journal-title":"J Clin Oncol"},{"issue":"3","key":"671_CR7","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1097\/MPH.0b013e318270b210","volume":"35","author":"AA Tantawy","year":"2013","unstructured":"Tantawy AA, et al. Spinal cord compression in childhood pediatric malignancies: multicenter egyptian study. J Pediatr Hematol Oncol. 2013;35(3):232\u20136.","journal-title":"J Pediatr Hematol Oncol"},{"issue":"6","key":"671_CR8","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/08880010390220126","volume":"20","author":"D Pollono","year":"2003","unstructured":"Pollono D, et al. Spinal cord compression: a review of 70 pediatric patients. Pediatr Hematol Oncol. 2003;20(6):457\u201366.","journal-title":"Pediatr Hematol Oncol"},{"issue":"1","key":"671_CR9","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s00381-008-0717-2","volume":"25","author":"D Gunes","year":"2009","unstructured":"Gunes D, et al. Paravertebral malignant tumors of childhood: analysis of 28 pediatric patients. Childs Nerv Syst. 2009;25(1):63\u20139.","journal-title":"Childs Nerv Syst"},{"issue":"4","key":"671_CR10","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1111\/j.1469-8749.2012.04219.x","volume":"54","author":"T Simon","year":"2012","unstructured":"Simon T, et al. Short- and long-term outcome of patients with symptoms of spinal cord compression by neuroblastoma. Dev Med Child Neurol. 2012;54(4):347\u201352.","journal-title":"Dev Med Child Neurol"},{"issue":"2","key":"671_CR11","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/sc.2012.160","volume":"52","author":"PW New","year":"2014","unstructured":"New PW, Marshall R. International spinal cord injury data sets for non-traumatic spinal cord injury. Spinal Cord. 2014;52(2):123\u201332.","journal-title":"Spinal Cord"},{"key":"671_CR12","first-page":"966","volume-title":"Pediatric Neurology: Principles and Practice","author":"NP Rosman","year":"1999","unstructured":"Rosman NP. G.H., Spinal Cord Injury. In: Swaiman KF, Ashwal S, editors. Pediatric Neurology: Principles and Practice, vol. 954. 3rd ed. St Louis: MO: Mosby; 1999. p. 966.","edition":"3"},{"issue":"3","key":"671_CR13","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1542\/peds.78.3.438","volume":"78","author":"DW Lewis","year":"1986","unstructured":"Lewis DW, et al. Incidence, presentation, and outcome of spinal cord disease in children with systemic cancer. Pediatrics. 1986;78(3):438\u201343.","journal-title":"Pediatrics"},{"issue":"1","key":"671_CR14","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3171\/jns.1991.74.1.0070","volume":"74","author":"SL Klein","year":"1991","unstructured":"Klein SL, Sanford RA, Muhlbauer MS. Pediatric spinal epidural metastases. J Neurosurg. 1991;74(1):70\u20135.","journal-title":"J Neurosurg"},{"issue":"8","key":"671_CR15","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1002\/pbc.25028","volume":"61","author":"B De Bernardi","year":"2014","unstructured":"De Bernardi B, et al. Neuroblastoma with symptomatic epidural compression in the infant: the AIEOP experience. Pediatr Blood Cancer. 2014;61(8):1369\u201375.","journal-title":"Pediatr Blood Cancer"},{"issue":"3","key":"671_CR16","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.hoc.2010.03.011","volume":"24","author":"H Sun","year":"2010","unstructured":"Sun H, Nemecek AN. Optimal management of malignant epidural spinal cord compression. Hematol Oncol Clin North Am. 2010;24(3):537\u201351.","journal-title":"Hematol Oncol Clin North Am"},{"issue":"8","key":"671_CR17","doi-asserted-by":"publisher","first-page":"e26451","DOI":"10.1002\/pbc.26451","volume":"64","author":"Kathelijne Kraal","year":"2017","unstructured":"Kraal K, et al. Treatment and outcome of neuroblastoma with intraspinal extension: a systematic review. Pediatr Blood Cancer. 2017;64(8):e26451.","journal-title":"Pediatric Blood & Cancer"},{"issue":"2","key":"671_CR18","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/S0022-3476(84)80996-8","volume":"104","author":"FA Hayes","year":"1984","unstructured":"Hayes FA, et al. Chemotherapy as an alternative to laminectomy and radiation in the management of epidural tumor. J Pediatr. 1984;104(2):221\u20134.","journal-title":"J Pediatr"},{"issue":"5","key":"671_CR19","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1227\/NEU.0000000000000903","volume":"77","author":"L Mirzaei","year":"2015","unstructured":"Mirzaei L, et al. The neurological compromised spine due to Ewing sarcoma. What first: surgery or chemotherapy? Therapy, survival, and neurological outcome of 15 cases with primary Ewing sarcoma of the vertebral column. Neurosurgery. 2015;77(5):718\u201324; discussion 724-5.","journal-title":"Neurosurgery"}],"container-title":["Italian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-019-0671-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13052-019-0671-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-019-0671-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T20:12:48Z","timestamp":1663963968000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijponline.biomedcentral.com\/articles\/10.1186\/s13052-019-0671-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,12]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["671"],"URL":"https:\/\/doi.org\/10.1186\/s13052-019-0671-5","relation":{},"ISSN":["1824-7288"],"issn-type":[{"value":"1824-7288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,12]]},"assertion":[{"value":"8 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the Santobono-Pausilipon Children\u2019s Hospital Ethics Committee. The guardian (parents) of the patient consented to both participation and publication of the case.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent was obtained from the guardian (parents), who agreed to join this study, and using the medical information for scientific research and publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"80"}}