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However, in addition to respiratory manifestations, it may also develop extra-pulmonary complications. Embolism is one of the uncommon extra-respiratory manifestations prone to severe sequelae and even death. This study aims to analyze the clinical features of MPP with embolism in children, and explore the associated risk factors of embolism in MPP patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective case\u2013control analysis was performed on 48 children with MPP admitted to our hospital wards between January 2010 and December 2021. Embolism group comprised children with embolism by CTA or MRA results, whereas the non-embolism group comprised children with clinical suspicion of embolism but negative diagnostic imaging support. The clinical features, laboratory findings and imaging were analyzed to explore the risk factors for embolism in children with MPP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 48 children with MPP were enrolled in the study (16 cases and 32 controls). In the embolism group, 10 patients (62.5%) had pulmonary embolism, 3 patients (18.75%) presented ventricle embolism, 2 patients (12.5%) presented cerebral and carotid artery embolism, one patient (6.25%) had a cerebral embolism, limb, and spleen, respectively. The univariate analysis revealed the maximum body temperature (Tmax), CRP, D-dimer (closest to CTA\/MRA), the percentage of neutrophils (N%), pulmonary consolidation (\u2a7e 2\/3 lobe), pleural effusion and atelectasis have significant differences between the embolism group and non-embolism group (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Multivariate logistic regression analysis showed that D-dimer (closest to CTA\/MRA)\u2009&gt;\u20093.55\u00a0mg\/L [OR\u2009=\u20091.255 (95% CI: 1.025\u20141.537),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05], pulmonary consolidation (\u2a7e 2\/3 lobe) [OR\u2009=\u20098.050 (95% CI: 1.341\u201448.327),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05], and pleural effusion [OR\u2009=\u200925.321 (95% CI: 2.738\u2014234.205),\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01] were independent risk factors for embolism in children with MPP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In conclusion, MPP with embolism patients have more D-dimer values and severe radiologic manifestations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13052-022-01344-0","type":"journal-article","created":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T03:03:03Z","timestamp":1660964583000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Analysis of the risk factors and clinical features of Mycoplasma pneumoniae pneumonia with embolism in children: a retrospective study"],"prefix":"10.1186","volume":"48","author":[{"given":"Chunjiao","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongqiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiafeng","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-331X","authenticated-orcid":false,"given":"Wei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongsheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,20]]},"reference":[{"issue":"4\u20135","key":"1344_CR1","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s12026-019-09096-6","volume":"67","author":"Z Wang","year":"2019","unstructured":"Wang Z, Yang L, Ye J, Wang Y, Liu Y. 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