{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T15:51:36Z","timestamp":1740153096392,"version":"3.37.3"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ital J Pediatr"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cholestasis in extremely premature infants (EPI) constitutes a nutritional challenge and maltodextrins have been reported as a possible strategy for hypoglycaemia. We aim to describe the nutritional management of an EPI with non-syndromic bile duct paucity (NSBDP) and feeding intolerance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A patient, born at 27\u00a0weeks of gestational age, presented cholestatic jaundice at 20\u00a0days of life with a clinical picture of NSBDP. Patient\u2019s growth was insufficient with formula rich in medium-chain triglyceride (MCT) and branched-chain amino acids (BCAA). Due to frequent fasting hypoglicemic episodes, maltodextrins supplements were provided. He subsequently presented severe abdominal distension and painful crises, which required hospital admission and withdrawal of maltodextrins. Hypercaloric extensively hydrolysed formula provided weight gain, glycemic control, and parallel improvement in cholestasis<jats:bold>.<\/jats:bold><\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our case suggests caution with the use of maltodextrins in infants, especially if premature. Commercial preparations for hepatopatic patients contain higher concentrations of MCTs and BCAAs, but personalized strategies must be tailored to each patient.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13052-022-01358-8","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T19:02:27Z","timestamp":1663268547000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Non-syndromic bile duct paucity and non-IgE cow\u2019s milk allergy: a case report of challenging nutritional management and maltodextrin intolerance"],"prefix":"10.1186","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8123-7522","authenticated-orcid":false,"given":"Irene","family":"Degrassi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina Chiara","family":"Pascuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enza","family":"D\u2019Auria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Fiori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Dilillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Lista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca Maria","family":"Castoldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Cavigioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Bosetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Pellegrinelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Vincenzo","family":"Zuccotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvira","family":"Verduci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,9,15]]},"reference":[{"key":"1358_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.clnesp.2019.01.006","volume":"30","author":"M Niccum","year":"2019","unstructured":"Niccum M, Khan MN, Middleton JP, Vergales BD, Syed S. Cholestasis affects enteral tolerance and prospective weight gain in the NICU. Clin Nutr ESPEN. 2019;30:119\u201325.","journal-title":"Clin Nutr ESPEN"},{"key":"1358_CR2","doi-asserted-by":"publisher","first-page":"2785","DOI":"10.3390\/nu13082785","volume":"13","author":"M Tessitore","year":"2021","unstructured":"Tessitore M, Sorrentino E, Schiano Di Cola G, Colucci A, Vajro P, Mandato C. Malnutrition in Pediatric Chronic Cholestatic Disease: An Up-to-Date Overview. Nutrients. 2021;13:2785.","journal-title":"Nutrients."},{"key":"1358_CR3","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1007\/s00431-018-3181-3","volume":"177","author":"BL Meena","year":"2018","unstructured":"Meena BL, Khanna R, Bihari C, Rastogi A, Rawat D, Alam S. Bile duct paucity in childhood-spectrum, profile, and outcome. Eur J Pediatr. 2018;177:1261\u20139.","journal-title":"Eur J Pediatr"},{"doi-asserted-by":"crossref","unstructured":"Nastasio S, Maggiore G. Cholestasis in preterm infants: when is a yellow alert? Ital J Pediatr. 2014;40:A12, 1824\u20137288\u201340-S2-A12.","key":"1358_CR4","DOI":"10.1186\/1824-7288-40-S2-A12"},{"key":"1358_CR5","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1111\/j.1651-2227.2009.01464.x","volume":"98","author":"M Tufano","year":"2009","unstructured":"Tufano M, Nicastro E, Giliberti P, Vegnente A, Raimondi F, Iorio R. Cholestasis in neonatal intensive care unit: incidence, aetiology and management. Acta Paediatr. 2009;98:1756\u201361.","journal-title":"Acta Paediatr"},{"key":"1358_CR6","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1097\/MPG.0000000000002443","volume":"69","author":"M Mouzaki","year":"2019","unstructured":"Mouzaki M, Bronsky J, Gupte G, Hojsak I, Jahnel J, Pai N, et al. Nutrition Support of Children With Chronic Liver Diseases: A Joint Position Paper of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2019;69:498\u2013511.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1358_CR7","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1053\/j.semdp.2019.07.004","volume":"36","author":"S-J Cho","year":"2019","unstructured":"Cho S-J, Kim GE. A practical approach to the pathology of neonatal cholestatic liver disease. Semin Diagn Pathol. 2019;36:375\u201388.","journal-title":"Semin Diagn Pathol"},{"key":"1358_CR8","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1002\/hep.1840150514","volume":"15","author":"M Bruguera","year":"1992","unstructured":"Bruguera M, Llach J, Rod\u00e9s J. Nonsyndromic paucity of intrahepatic bile ducts in infancy and idiopathic ductopenia in adulthood: the same syndrome? Hepatology. 1992;15:830\u20134.","journal-title":"Hepatology"},{"key":"1358_CR9","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1111\/j.1440-1746.1996.tb00287.x","volume":"11","author":"HH Chiu","year":"1996","unstructured":"Chiu HH, Chang MH, Chen CL, Hsu HY, Ni YH. Case report: paucity of interlobular bile ducts in Chinese children. J Gastroenterol Hepatol. 1996;11:434\u20138.","journal-title":"J Gastroenterol Hepatol"},{"key":"1358_CR10","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1097\/00005176-199701000-00011","volume":"24","author":"N Ko\u00e7ak","year":"1997","unstructured":"Ko\u00e7ak N, G\u00fcrakan F, Y\u00fcce A, \u00c7aglar M, Kale G, G\u00f6g\u00fcs S. Nonsyndromic Paucity of Interlobular Bile Ducts: Clinical and Laboratory Findings of 10 Cases. J Pediatr Gastroenterol Nutr. 1997;24:44\u20138.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1358_CR11","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1097\/00005176-200311000-00007","volume":"37","author":"V Yehezkely-Schildkraut","year":"2003","unstructured":"Yehezkely-Schildkraut V, Munichor M, Mandel H, Berkowitz D, Hartman C, Eshach-Adiv O, et al. Nonsyndromic paucity of interlobular bile ducts: report of 10 patients. J Pediatr Gastroenterol Nutr. 2003;37:546\u20139.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1358_CR12","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1590\/S0004-28032004000300010","volume":"41","author":"AMA De Tommaso","year":"2004","unstructured":"De Tommaso AMA, Kawasaki AS, Hessel G. Paucity of intrahepatic bile ducts in infancy\u2013experience of a tertiary center. Arq Gastroenterol. 2004;41:190\u20132.","journal-title":"Arq Gastroenterol"},{"key":"1358_CR13","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1080\/15513815.2019.1652376","volume":"39","author":"S Mohanty","year":"2020","unstructured":"Mohanty S, Das K, Anne Correa MM. Non Syndromic Paucity of Interlobular Bile Ducts in Children - A Clinicopathological Study. Fetal Pediatr Pathol. 2020;39:317\u201333.","journal-title":"Fetal Pediatr Pathol"},{"issue":"Suppl 2","key":"1358_CR14","doi-asserted-by":"publisher","first-page":"S89","DOI":"10.1097\/00005176-200208002-00005","volume":"35","author":"FJ Suchy","year":"2002","unstructured":"Suchy FJ, Burdelski M, Tomar BS, Sokol RJ. Cholestatic liver disease: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2002;35(Suppl 2):S89-97.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1358_CR15","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1111\/j.1399-3046.2007.00792.x","volume":"11","author":"A Baker","year":"2007","unstructured":"Baker A, Stevenson R, Dhawan A, Goncalves I, Socha P, Sokal E. Guidelines for nutritional care for infants with cholestatic liver disease before liver transplantation. Pediatr Transplant. 2007;11:825\u201334.","journal-title":"Pediatr Transplant"},{"key":"1358_CR16","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1097\/MPG.0000000000001707","volume":"66","author":"RK Buddington","year":"2018","unstructured":"Buddington RK, Davis SL, Buddington KK. The Risk of Necrotizing Enterocolitis Differs Among Preterm Pigs Fed Formulas With Either Lactose or Maltodextrin. J Pediatr Gastroenterol Nutr. 2018;66:e61\u20136.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1358_CR17","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.anai.2012.02.001","volume":"108","author":"C Caffarelli","year":"2012","unstructured":"Caffarelli C, Ric\u00f2 S, Rinaldi L, et al. Blood pressure monitoring in children undergoing food challenge: association with anaphylaxis. Ann Allergy Asthma Immunol. 2012;108:285\u20136.","journal-title":"Ann Allergy Asthma Immunol"}],"container-title":["Italian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-022-01358-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13052-022-01358-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-022-01358-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T19:06:14Z","timestamp":1663268774000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijponline.biomedcentral.com\/articles\/10.1186\/s13052-022-01358-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,15]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["1358"],"URL":"https:\/\/doi.org\/10.1186\/s13052-022-01358-8","relation":{},"ISSN":["1824-7288"],"issn-type":[{"type":"electronic","value":"1824-7288"}],"subject":[],"published":{"date-parts":[[2022,9,15]]},"assertion":[{"value":"26 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patients\u2019 parents have provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"175"}}