{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:04:07Z","timestamp":1790193847064,"version":"4.1.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Ital J Pediatr"],"DOI":"10.1186\/s13052-025-02094-5","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T20:49:05Z","timestamp":1754167745000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A predictive model for prognosis in infants with surgical necrotizing enterocolitis"],"prefix":"10.1186","volume":"51","author":[{"given":"Jin Yu","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Rong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei Yue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"2094_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jpeds.2019.12.035","volume":"220","author":"C Flahive","year":"2020","unstructured":"Flahive C, Schlegel A, Mezoff EA. Necrotizing enterocolitis: updates on morbidity and mortality outcomes. J Pediatr. 2020;220:7\u20139.","journal-title":"J Pediatr"},{"issue":"1","key":"2094_CR2","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/s12887-017-0847-3","volume":"17","author":"N Samuels","year":"2017","unstructured":"Samuels N, van de Graaf RA, de Jonge RCJ, et al. Risk factors for necrotizing Enterocolitis in neonates: a systematic review of prognostic studies. BMC Pediatr. 2017;17(1):105.","journal-title":"BMC Pediatr"},{"issue":"3","key":"2094_CR3","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1056\/NEJMra1005408","volume":"364","author":"J Neu","year":"2011","unstructured":"Neu J, Walker WA. Necrotizing Enterocolitis. N Engl J Med. 2011;364(3):255\u201364.","journal-title":"N Engl J Med"},{"issue":"1","key":"2094_CR4","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1186\/s12887-020-02231-5","volume":"20","author":"A Alsaied","year":"2020","unstructured":"Alsaied A, Islam N, Thalib L. Global incidence of necrotizing enterocolitis: a systematic review and Meta-analysis. BMC Pediatr. 2020;20(1):344.","journal-title":"BMC Pediatr"},{"issue":"2","key":"2094_CR5","doi-asserted-by":"publisher","first-page":"F182","DOI":"10.1136\/archdischild-2017-313880","volume":"103","author":"C Battersby","year":"2018","unstructured":"Battersby C, Santhalingam T, Costeloe K, et al. Incidence of neonatal necrotising Enterocolitis in high-income countries: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2018;103(2):F182\u20139.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"9","key":"2094_CR6","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.2165\/00003495-200868090-00004","volume":"68","author":"AM Thompson","year":"2008","unstructured":"Thompson AM, Bizzarro MJ. Necrotizing Enterocolitis in newborns: pathogenesis, prevention and management. Drugs. 2008;68(9):1227\u201338.","journal-title":"Drugs"},{"key":"2094_CR7","doi-asserted-by":"crossref","unstructured":"Bethell GS, Hall NJ, Battersby C et al. Surgeons and neonatologists views about surgical decision-making in necrotising Enterocolitis. Arch Dis Child Fetal Neonatal Ed. 2025:fetalneonatal\u20132025.","DOI":"10.1136\/archdischild-2025-328480"},{"issue":"1","key":"2094_CR8","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1159\/000355064","volume":"105","author":"A Muller","year":"2014","unstructured":"Muller A, Schurink M, Bos AF, et al. Clinical importance of a fixed bowel loop in the treatment of necrotizing Enterocolitis. Neonatology. 2014;105(1):33\u20138.","journal-title":"Neonatology"},{"issue":"5","key":"2094_CR9","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1016\/j.jamcollsurg.2010.01.008","volume":"210","author":"JJ Tepas","year":"2010","unstructured":"Tepas JJ 3rd, Leaphart CL, Plumley D, et al. Trajectory of metabolic derangement in infants with necrotizing Enterocolitis should drive timing and technique of surgical intervention. J Am Coll Surg. 2010;210(5):847\u201352.","journal-title":"J Am Coll Surg"},{"issue":"1","key":"2094_CR10","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/S2468-1253(16)30117-0","volume":"2","author":"C Battersby","year":"2017","unstructured":"Battersby C, Longford N, Mandalia S, et al. Modi N; UK neonatal collaborative necrotising Enterocolitis (UKNC-NEC) study group. Incidence and enteral feed antecedents of severe neonatal necrotising Enterocolitis across neonatal networks in england, 2012-13: a whole-population surveillance study. Lancet Gastroenterol Hepatol. 2017;2(1):43\u201351.","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"1","key":"2094_CR11","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1067\/j.cpsurg.2018.11.005","volume":"56","author":"J Knell","year":"2019","unstructured":"Knell J, Han SM, Jaksic T, et al. Current status of necrotizing Enterocolitis. Curr Probl Surg. 2019;56(1):11\u201338.","journal-title":"Curr Probl Surg"},{"key":"2094_CR12","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.jpeds.2019.11.011","volume":"220","author":"IH Jones","year":"2020","unstructured":"Jones IH, Hall NJ. Contemporary outcomes for infants with necrotizing enterocolitis-a systematic review. J Pediatr. 2020;220:86\u2013e923.","journal-title":"J Pediatr"},{"issue":"7","key":"2094_CR13","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1016\/0022-3468(95)90328-3","volume":"30","author":"JR Horwitz","year":"1995","unstructured":"Horwitz JR, Lally KP, Cheu HW, et al. Complications after surgical intervention for necrotizing enterocolitis: a multicenter review. J Pediatr Surg. 1995;30(7):994\u20138. discussion 998-9.","journal-title":"J Pediatr Surg"},{"issue":"2","key":"2094_CR14","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1055\/s-0038-1636943","volume":"28","author":"A Mutanen","year":"2018","unstructured":"Mutanen A, Pierro A, Zani A. Perioperative complications following surgery for necrotizing Enterocolitis. Eur J Pediatr Surg. 2018;28(2):148\u201351.","journal-title":"Eur J Pediatr Surg"},{"issue":"12","key":"2094_CR15","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1038\/sj.jp.7211613","volume":"26","author":"U Kessler","year":"2006","unstructured":"Kessler U, Mungnirandr A, Nelle M, et al. A simple presurgical necrotizing enterocolitis-mortality scoring system. J Perinatol. 2006;26(12):764\u20138.","journal-title":"J Perinatol"},{"issue":"4","key":"2094_CR16","doi-asserted-by":"publisher","first-page":"e876","DOI":"10.1542\/peds.2013-0702","volume":"132","author":"WJ Ge","year":"2013","unstructured":"Ge WJ, Mirea L, Yang J, et al. Canadian neonatal network. Prediction of neonatal outcomes in extremely preterm neonates. Pediatrics. 2013;132(4):e876\u201385.","journal-title":"Pediatrics"},{"issue":"4","key":"2094_CR17","first-page":"213","volume":"17","author":"RM Kliegman","year":"1987","unstructured":"Kliegman RM, Walsh MC. Neonatal necrotizing enterocolitis: pathogenesis, classification, and spectrum of illness. Curr Probl Pediatr. 1987;17(4):213\u201388.","journal-title":"Curr Probl Pediatr"},{"issue":"1","key":"2094_CR18","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.clp.2012.12.003","volume":"40","author":"SC Amin","year":"2013","unstructured":"Amin SC, Pappas C, Iyengar H, et al. Short bowel syndrome in the NICU. Clin Perinatol. 2013;40(1):53\u201368.","journal-title":"Clin Perinatol"},{"issue":"1","key":"2094_CR19","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/S0022-3476(72)80459-1","volume":"80","author":"DW Wilmore","year":"1972","unstructured":"Wilmore DW. Factors correlating with a successful outcome following extensive intestinal resection in newborn infants. J Pediatr. 1972;80(1):88\u201395.","journal-title":"J Pediatr"},{"issue":"2","key":"2094_CR20","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.jpeds.2004.02.030","volume":"145","author":"RE Quir\u00f3s-Tejeira","year":"2004","unstructured":"Quir\u00f3s-Tejeira RE, Ament ME, Reyen L, et al. Long-term parenteral nutritional support and intestinal adaptation in children with short bowel syndrome: a 25-year experience. J Pediatr. 2004;145(2):157\u201363.","journal-title":"J Pediatr"},{"issue":"2","key":"2094_CR21","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/S0022-3476(83)80366-7","volume":"103","author":"LA Papile","year":"1983","unstructured":"Papile LA, Munsick-Bruno G, Schaefer A. Relationship of cerebral intraventricular hemorrhage and early childhood neurologic handicaps. J Pediatr. 1983;103(2):273\u20137.","journal-title":"J Pediatr"},{"issue":"10","key":"2094_CR22","doi-asserted-by":"publisher","first-page":"e51","DOI":"10.1016\/j.ophtha.2021.05.031","volume":"128","author":"MF Chiang","year":"2021","unstructured":"Chiang MF, Quinn GE, Fielder AR, et al. International classification of retinopathy of prematurity, third edition. Ophthalmology. 2021;128(10):e51\u201368.","journal-title":"Ophthalmology"},{"issue":"6","key":"2094_CR23","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1542\/peds.2005-0249","volume":"116","author":"RA Ehrenkranz","year":"2005","unstructured":"Ehrenkranz RA, Walsh MC, Vohr BR, et al. National institutes of child health and human development neonatal research network. Validation of the National institutes of health consensus definition of bronchopulmonary dysplasia. Pediatrics. 2005;116(6):1353\u201360.","journal-title":"Pediatrics"},{"key":"2094_CR24","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.jpeds.2018.01.043","volume":"197","author":"RD Higgins","year":"2018","unstructured":"Higgins RD, Jobe AH, Koso-Thomas M, et al. Bronchopulmonary dysplasia: executive summary of a workshop. J Pediatr. 2018;197:300\u20138.","journal-title":"J Pediatr"},{"issue":"9","key":"2094_CR25","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1001\/jama.2016.1204","volume":"315","author":"RM Patel","year":"2016","unstructured":"Patel RM, Knezevic A, Shenvi N, et al. Association of red blood cell transfusion, anemia, and necrotizing Enterocolitis in very low-birth-weight infants. JAMA. 2016;315(9):889\u201397.","journal-title":"JAMA"},{"issue":"3","key":"2094_CR26","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1542\/peds.2004-0569","volume":"115","author":"SR Hintz","year":"2005","unstructured":"Hintz SR, Kendrick DE, Stoll BJ, et al. NICHD neonatal research network. Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing Enterocolitis. Pediatrics. 2005;115(3):696\u2013703.","journal-title":"Pediatrics"},{"key":"2094_CR27","doi-asserted-by":"crossref","unstructured":"Crissinger KD. Animal models of necrotizing Enterocolitis. J Pediatr Gastroenterol Nutr. 1995;(1):17\u201322.","DOI":"10.1002\/j.1536-4801.1995.tb11483.x"},{"issue":"17","key":"2094_CR28","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1056\/NEJM198404263101707","volume":"310","author":"RM Kliegman","year":"1984","unstructured":"Kliegman RM, Fanaroff AA. Necrotizing Enterocolitis. N Engl J Med. 1984;310(17):1093\u2013103.","journal-title":"N Engl J Med"},{"issue":"4","key":"2094_CR29","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1046\/j.1365-3016.2002.00445.x","volume":"16","author":"AR Llanos","year":"2002","unstructured":"Llanos AR, Moss ME, Pinz\u00f2n MC, et al. Epidemiology of neonatal necrotising enterocolitis: a population-based study. Paediatr Perinat Epidemiol. 2002;16(4):342\u20139.","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"3","key":"2094_CR30","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1001\/jama.2021.23580","volume":"327","author":"EF Bell","year":"2022","unstructured":"Bell EF, Hintz SR, Hansen NI, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Mortality, et al. -hospital morbidity, care practices, and 2-year outcomes for extremely preterm infants in the US, 2013\u20132018. JAMA. 2022;327(3):248\u201363.","journal-title":"JAMA"},{"issue":"2","key":"2094_CR31","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.jpeds.2010.02.023","volume":"157","author":"D Duro","year":"2010","unstructured":"Duro D, Kalish LA, Johnston P, et al. Risk factors for intestinal failure in infants with necrotizing enterocolitis: a glaser pediatric research network study. J Pediatr. 2010;157(2):203\u2013e2081.","journal-title":"J Pediatr"},{"issue":"5","key":"2094_CR32","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1542\/peds.2009-3506","volume":"125","author":"SE Hamrick","year":"2010","unstructured":"Hamrick SE, Hansmann G. Patent ductus arteriosus of the preterm infant. Pediatrics. 2010;125(5):1020\u201330.","journal-title":"Pediatrics"},{"issue":"1","key":"2094_CR33","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13052-021-00956-2","volume":"47","author":"G Terrin","year":"2021","unstructured":"Terrin G, Di Chiara M, Boscarino G, et al. Morbidity associated with patent ductus arteriosus in preterm newborns: a retrospective case-control study. Ital J Pediatr. 2021;47(1):9.","journal-title":"Ital J Pediatr"},{"issue":"1","key":"2094_CR34","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s12519-015-0059-6","volume":"12","author":"U Kessler","year":"2016","unstructured":"Kessler U, Schulte F, Cholewa D, et al. Outcome in neonates with necrotizing Enterocolitis and patent ductus arteriosus. World J Pediatr. 2016;12(1):55\u20139.","journal-title":"World J Pediatr"},{"issue":"2","key":"2094_CR35","first-page":"184","volume":"40","author":"S Dollberg","year":"2005","unstructured":"Dollberg S, Lusky A, Reichman B. Patent ductus arteriosus, indomethacin and necrotizing Enterocolitis in very low birth weight infants: a population-based study. J Pediatr Gastroenterol Nutr. 2005;40(2):184\u20138.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"5 Pt 2","key":"2094_CR36","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/S0022-3476(79)80454-0","volume":"95","author":"ER Brown","year":"1979","unstructured":"Brown ER. Increased risk of bronchopulmonary dysplasia in infants with patent ductus arteriosus. J Pediatr. 1979;95(5 Pt 2):865\u20136.","journal-title":"J Pediatr"},{"issue":"6","key":"2094_CR37","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1542\/peds.69.6.778","volume":"69","author":"B Lipman","year":"1982","unstructured":"Lipman B, Serwer GA, Brazy JE. Abnormal cerebral hemodynamics in preterm infants with patent ductus arteriosus. Pediatrics. 1982;69(6):778\u201381.","journal-title":"Pediatrics"},{"issue":"4","key":"2094_CR38","first-page":"CD013588","volume":"4","author":"S Mitra","year":"2023","unstructured":"Mitra S, de Boode WP, Weisz DE, et al. Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane systematic reviews. Cochrane Database Syst Rev. 2023;4(4):CD013588.","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"2094_CR39","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1016\/j.jpedsurg.2005.12.034","volume":"41","author":"M H\u00e4llstr\u00f6m","year":"2006","unstructured":"H\u00e4llstr\u00f6m M, Koivisto AM, Janas M, et al. Laboratory parameters predictive of developing necrotizing Enterocolitis in infants born before 33 weeks of gestation. J Pediatr Surg. 2006;41(4):792\u20138.","journal-title":"J Pediatr Surg"},{"issue":"1","key":"2094_CR40","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.pathophys.2013.11.010","volume":"21","author":"CJ Hunter","year":"2014","unstructured":"Hunter CJ, De Plaen IG. Inflammatory signaling in NEC: role of NF-\u03baB, cytokines and other inflammatory mediators. Pathophysiology. 2014;21(1):55\u201365.","journal-title":"Pathophysiology"},{"issue":"2","key":"2094_CR41","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/S0022-3468(97)90194-9","volume":"32","author":"H Ford","year":"1997","unstructured":"Ford H, Watkins S, Reblock K, et al. The role of inflammatory cytokines and nitric oxide in the pathogenesis of necrotizing Enterocolitis. J Pediatr Surg. 1997;32(2):275\u201382.","journal-title":"J Pediatr Surg"},{"issue":"6","key":"2094_CR42","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1038\/s41390-021-01903-x","volume":"91","author":"WS Kalteren","year":"2022","unstructured":"Kalteren WS, Bos AF, van Oeveren W, et al. Neonatal anemia relates to intestinal injury in preterm infants. Pediatr Res. 2022;91(6):1452\u20138.","journal-title":"Pediatr Res"},{"issue":"1","key":"2094_CR43","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1186\/s13054-022-04191-x","volume":"26","author":"AA Quispe-Cornejo","year":"2022","unstructured":"Quispe-Cornejo AA, Alves da Cunha AL, Njimi H, et al. Effects of rapid fluid infusion on hemoglobin concentration: a systematic review and meta-analysis. Crit Care. 2022;26(1):324.","journal-title":"Crit Care"},{"issue":"1","key":"2094_CR44","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s13741-020-00171-3","volume":"9","author":"D Astapenko","year":"2020","unstructured":"Astapenko D, Navratil P, Pouska J, et al. Clinical physiology aspects of chloremia in fluid therapy: a systematic review. Perioper Med (Lond). 2020;9(1):40.","journal-title":"Perioper Med (Lond)"},{"key":"2094_CR45","doi-asserted-by":"publisher","first-page":"474185","DOI":"10.1100\/2012\/474185","volume":"2012","author":"M Tani","year":"2012","unstructured":"Tani M, Morimatsu H, Takatsu F, et al. The incidence and prognostic value of hypochloremia in critically ill patients. ScientificWorldJournal. 2012;2012:474185.","journal-title":"ScientificWorldJournal"},{"issue":"5","key":"2094_CR46","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1172\/JCI10318","volume":"106","author":"HF Cheng","year":"2000","unstructured":"Cheng HF, Wang JL, Zhang MZ, et al. Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride. J Clin Invest. 2000;106(5):681\u20138.","journal-title":"J Clin Invest"},{"issue":"23","key":"2094_CR47","doi-asserted-by":"publisher","first-page":"6031","DOI":"10.3390\/ijms20236031","volume":"20","author":"TC Martinsen","year":"2019","unstructured":"Martinsen TC, Fossmark R, Waldum HL. The phylogeny and biological function of gastric juice-microbiological consequences of removing gastric acid. Int J Mol Sci. 2019;20(23):6031.","journal-title":"Int J Mol Sci"},{"issue":"13","key":"2094_CR48","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1056\/NEJMp048026","volume":"350","author":"DG Bichet","year":"2004","unstructured":"Bichet DG, Fujiwara TM. Reabsorption of sodium chloride\u2013lessons from the chloride channels. N Engl J Med. 2004;350(13):1281\u20133.","journal-title":"N Engl J Med"},{"issue":"5","key":"2094_CR49","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1186\/cc2900","volume":"8","author":"JA Kellum","year":"2004","unstructured":"Kellum JA, Song M, Li J. Science review: extracellular acidosis and the immune response: clinical and physiologic implications. Crit Care. 2004;8(5):331\u20136.","journal-title":"Crit Care"},{"issue":"20","key":"2094_CR50","doi-asserted-by":"publisher","first-page":"12825","DOI":"10.1073\/pnas.202474099","volume":"99","author":"LA Kubasiak","year":"2002","unstructured":"Kubasiak LA, Hernandez OM, Bishopric NH, et al. Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc Natl Acad Sci U S A. 2002;99(20):12825\u201330.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2094_CR51","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1146\/annurev.med.60.050207.092824","volume":"60","author":"MC Henry","year":"2009","unstructured":"Henry MC, Moss RL. Necrotizing Enterocolitis. Annu Rev Med. 2009;60:111\u201324.","journal-title":"Annu Rev Med"},{"issue":"2","key":"2094_CR52","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1542\/peds.78.2.273","volume":"78","author":"R Buras","year":"1986","unstructured":"Buras R, Guzzetta P, Avery G, et al. Acidosis and hepatic portal venous gas: indications for surgery in necrotizing Enterocolitis. Pediatrics. 1986;78(2):273\u20137.","journal-title":"Pediatrics"},{"issue":"5","key":"2094_CR53","doi-asserted-by":"publisher","first-page":"F461","DOI":"10.1136\/archdischild-2017-313113","volume":"103","author":"BSR Allin","year":"2018","unstructured":"Allin BSR, Long AM, Gupta A, et al. One-year outcomes following surgery for necrotising enterocolitis: a UK-wide cohort study. Arch Dis Child Fetal Neonatal Ed. 2018;103(5):F461\u20136.","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"1","key":"2094_CR54","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s13052-021-01180-8","volume":"47","author":"G Savarino","year":"2021","unstructured":"Savarino G, Carta M, Cimador M, et al. Necrotizing Enterocolitis in the preterm: newborns medical and nutritional management in a single-center study. Ital J Pediatr. 2021;47(1):226.","journal-title":"Ital J Pediatr"}],"container-title":["Italian Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-025-02094-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13052-025-02094-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13052-025-02094-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T13:23:10Z","timestamp":1757337790000},"score":1,"resource":{"primary":{"URL":"https:\/\/ijponline.biomedcentral.com\/articles\/10.1186\/s13052-025-02094-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,2]]},"references-count":54,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["2094"],"URL":"https:\/\/doi.org\/10.1186\/s13052-025-02094-5","relation":{},"ISSN":["1824-7288"],"issn-type":[{"value":"1824-7288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,2]]},"assertion":[{"value":"7 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Approval for the present study was acquired from the Medical Ethic Committee of the First Affiliated Hospital of Anhui Medical University and Anhui Provincial Children\u2019s Hospital and obtained consent from parents of all subjects.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None of the authors have any conflicts of interest to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"245"}}