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Written informed consent was obtained from all patients or their legal representatives.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"No individual participant data are reported that would require consent to publish from the participant (or legal parent or guardian for children).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors have provided information on potential conflicts of interests directly or indirectly related to the work submitted in the journal\u2019s disclosure forms. AN reported receiving lecture honoraria from Thermo Fisher Scientific. FB reported receiving lecture honoraria from biosyn, Gilead and CSL Behring and public funding for the SISPCT trial to his department by the German Federal Ministry of Education and Research, as well as unrestricted research grants for the SISPCT trial by biosyn and Thermo Fisher Scientific. DCW is an employee of BRAHMS GmbH. The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"201"}}